Improved efficiency and selectivity in peptide synthesis: Use of triethylsilane as a carbocation scavenger in deprotection of t-butyl esters and t-butoxycarbonyl-protected sites

Tetrahedron Letters

Volumn 33, Issue 37, 1992, Pages 5441-5444

  Mehta, Anita ^a,b   Jaouhari, Rabih ^a   Benson, Timothy J ^a   Douglas, Kenneth T ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL;

EID: 0026709956     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)79116-7     Document Type: Article

References (12)

1. Die Synthese eines Tetracosapeptides mit der Aminos�uresequenz eines hochaktiven Abbauproduktes des ?-Corticotropins (ACTH) aus Schweinehypophysen. (Vorl�ufige Mitteilung)
2. Trifluoromethanesulphonic acid, as a deprotecting reagent in peptide chemistry
3. Improved selectivity in the removal of the tert.-butyloxycarbonyl group