The effect of EDTA and serum on endogenous porphyrin accumulation and photodynamic sensitization of human K562 leukemic cells

Cancer Letters

Volumn 65, Issue 2, 1992, Pages 127-131

  Hanania, Judith ^a   Malik, Zvi ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

aminolevulinic acid; endogenous porphyrin; K562 leukemia; photosensitization

Indexed keywords

AMINOLEVULINIC ACID; EDETIC ACID; FERROUS ION; PORPHYRIN;

ARTICLE; BIOACCUMULATION; CANCER CELL CULTURE; CELL STRAIN K 562; CELL VIABILITY; ETIOLOGY; FLUOROMETRY; HUMAN; HUMAN CELL; PHOTOSENSITIZATION; PRIORITY JOURNAL; SERUM;

AMINOLEVULINIC ACID; BLOOD; CELL LINE; CELL SURVIVAL; CULTURE MEDIA; EDETIC ACID; HUMAN; KINETICS; LEUKEMIA, MYELOID, CHRONIC; LIGHT; PORPHYRINS; SUPPORT, NON-U.S. GOV'T; ULTRAVIOLET RAYS;

EID: 0026699181     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(92)90156-P     Document Type: Article

References (11)

1. Radiochemical assay for 5-aminolevulinic synthase
2. Photodynamic therapy of superficial skin cancer using porphyrins generated by topical 5-aminolevulinic acid
3. 5-aminolevulinic acid stimulation of porhyrin and hemoglobin synthesis by uninduced Friend erythroleukemic cells
4. Inactivation of erythropoietic, lymphopoietc and myelocytic leukemic cells by photoexcitation of endogenous porphyrins
5. Selective destruction of erythroleukemic cells by photoactivation of endogenous porphyrins
6. Rapid calorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
7. A comparison of different photosensitizing dyes with respect to uptake in C3H-tumors and tissues of mice
8. Non invasive technique for obtaining florescence excitation and emission spectra in vivo
9. Glucose administration augments in vivo uptake and phototoxicity of the tumor-localizing fraction of hematoporphyrin derivative
10. Comparative porphyrin content in tumors with contiguous non-neoplastic tissues
11. Synthesis of haem in normal and leukemic leukocytes