Genetic Changes of Both p53 Alleles Associated with the Conversion from Colorectal Adenoma to Early Carcinoma in Familial Adenomatous Polyposis and Non-Familial Adenomatous Polyposis Patients

Cancer Research

Volumn 52, Issue 14, 1992, Pages 3965-3971

  Kikuchi Yanoshita, Rei ^a   Konishi, Motoko ^a   Ito, Satomi ^a   Seki, Madoka ^a   Tanaka, Kiyoko ^a   Maeda, Yoshiharu ^b   Iino, Hiroshi ^b   Fukayama, Masashi ^b   Koike, Morio ^b   Mori, Takeo ^b   Sakuraba, Hitoshi ^a   Fukunari, Hiroyuki ^c   Iwama, Takeo ^c   Miyaki, Michiko ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DNA; PROTEIN P53;

ADENOMA; ADENOMATOUS POLYP; ALLELE; ARTICLE; COLORECTAL CARCINOMA; DISEASE COURSE; DNA SEQUENCE; FAMILIAL POLYPOSIS; GENE EXPRESSION; HETEROZYGOSITY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; ALLELES; AMINO ACID SEQUENCE; CARCINOMA; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 17; COLORECTAL NEOPLASMS; GENES, P53; HETEROZYGOTE; HUMAN; MOLECULAR SEQUENCE DATA; MUTATION; RNA, MESSENGER; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T;

EID: 0026695813     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Okamoto, M., Sasaki, M., Sugio, K., Sato, C., Iwama, T., Ikeuchi, T., Tonomura. A., Sasazuki, T., and Miyaki, M. Loss of constitutional heterozygosity in colon carcinoma from patients with familial polyposis coli. Nature (Lond.), 331: 273-277, 1988.
2. Sasaki, M., Okamoto, M., Sato, C., Sugio, K., Soejima, J., Iwama, T., Ikeuchi, T., Tonomura, A., Miyaki, M., and Sasazuki, T. Loss of constitutional heterozygosity in colorectal tumors from patients with familial polyposis coli and those with nonpolyposis colorectal carcinoma. Cancer Res., 49: 4402-4406, 1989.
3. Miyaki, M., Seki, M., Okamoto, M., Yamanaka, A., Maeda, Y., Tanaka, K., Kikuchi, R., Iwama, T., Ikeuchi, T., Tonomura, A., Nakamura, Y., White, R., Miki, Y., Utsunomiya, J., and Koike, M. Genetic changes and histopatho-logical types in colorectal tumors from patients with familial adenomatous polyposis. Cancer Res., 50: 7166-7173, 1990.
4. Muleris, M., Salmon, R. J., Zafrani, B., Girodet, J., and Dutrillaux, B. Consistent deficiencies of chromosome 18 and of the short arm of chromosome 17 in eleven cases of human large bowel cancer: a possible recessive determinism. Ann. Genet., 28: 206-213, 1985.
5. Fearon, E. R., Hamilton, S. R., and Vogelstein, B. Clonal analysis of human colorectal tumors. Science (Washington DC), 258: 193-197, 1987.
6. Monpezat, J-P., Delattre, O., Bernard, A., Grunwald, D., Remvikos, Y., Muleris, M., Salmon, R. J., Frelat, G., Dutrillaux, B., and Thomas, G. Loss of alleles on chromosome 18 and on the short arm of chromosome 17 in polyploid colorectal carcinomas. Int. J. Cancer, 41: 404-408, 1988.
7. Law, D. J., Olschwang, S., Monpezat, J-P., Lefrancois, D., Jagelman, D., Petrelli, N. J., Thomas, G., and Feinberg, A. P. Concerted nonsyntenic allelic loss in human colorectal carcinoma. Science (Washington DC), 241: 961-965, 1988.
8. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M. M., and Bos, J. L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319: 525-532, 1988.
9. Fearon, E. R., and Vogelstein, B. A genetic model for colorectal tumorigen-esis. Cell, 61: 759-767, 1990.
10. vanTuinen, P., Dobyns, W. B., Rich, D. C., Summers, K. M., Robinson, T. J., Nakamura, Y., and Ledbetter, D. H. Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome. Am. J. Hum. Genet., 43: 587-596, 1988.
11. Baker, S. J., Fearon, E. R., Nigro, J. M., Hamilton, S. R., Preisinger, A. C., Jessup, J. M., vanTuinen, P., Ledbetter, D. H., Barker, D. F., Nakamura, Y., White, R., and Vogelstein, B. Chromosome 17 deletions and pS3 mutations in colorectal carcinomas. Science (Washington DC), 244: 217-221, 1989.
12. Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F. S., Weston, A., Modali, R., Harris, C. C., and Vogelstein, B. Mutations in the p53 gene occur in diverse human tumor types. Nature (Lond.), 342: 705-708, 1989.
13. Rodrigues, N. R., Rowan, A., Smith, M. E. F., Kerr, I. B., Bodmer, W. F., Gannon, J. V., and Lane, D. P. p53 mutations in colorectal cancer. Proc. Natl. Acad. Sci. USA, 87: 7555-7559, 1990.
14. Malkin, D., Li, F. P., Strong, L. C., Fraumeni, J. F., Jr., Nelson, C. E., Kim, D. H., Kassel, J., Gryka, M. A., Bischoff, F. Z., Tainsky, M. A., and Friend, S. H. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science (Washington DC), 250: 1233-1238, 1990.
15. Srivastava, S., Zou, Z., Pirollo, K., Blattner, W., and Chang, E. H. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Frau-meni syndrome. Nature (Lond.), 348: 747-749, 1990.
16. Takahashi, T., Nau, M. M., Chiba, I., Birrer, M. J., Rosenberg, R. K., Vinocour, M., Levitt, M., Pass, H., Gazdar, A. F., and Minna, J. D. p53\ a frequent target for genetic abnormalities in lung cancer. Science (Washington DC), 246: 491-494, 1989.
17. Hsu, I. C., Metcalf, R. A., Sun, T., Welsh, J. A., Wang, N. J., and Harris, C. C. Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature (Lond.), 350: 427-428, 1991.
18. Bressac, B., Kew, M., Wands, J., and Ozturk, M. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature (Lond.), 350: 429-431, 1991.
19. Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. C. p53 mutations in human cancers. Science (Washington DC), 253: 49-53, 1991.
20. Baker, S. J., Preisinger, A. C., Jessup, J. M., Paraskeva, C., Markowitz, S., Willson, J. K. V., Hamilton, S., and Vogelstein, B. p53 mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigen-esis. Cancer Res., 50: 7717-7722, 1990.
21. Japanese Research Society for Cancer of Colon and Rectum. General Rules for Clinical and Pathological Studies on Cancer of Colon, Rectum and Anus, Ed. 4. Tokyo: Kanehara, Inc., 1985.
22. Orita, M., Suzuki, Y., Sekiya, T., and Hayashi, K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics, 5: 874-879, 1989.
23. Suzuki, Y., Sekiya, T., and Hayashi, K. Allele-specific polymerase chain reaction: a method for amplification and sequence determination of a single component among a mixture of sequence variants. Anal. Biochem., 192: 82-84, 1991.
24. Gyllensten, L.I.B., and Erlich, H. A. Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc. Natl. Acad. Sci. USA, 85: 7652-7656, 1988.
25. Towbin, H., Staehelin, T., and Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76: 4350-4354, 1979.
26. Yamanaka, A., Takizawa, T., Maeda, Y., Iwasaki, Y., lino, H., Kato, S., Koike, M., Mori, T., Takahashi, T., Seki, M., and Miyaki M. Genetic changes and histopathological types in sporadic colorectal tumors from non-FAP patients. Proc. Jpn. Cancer Assoc., 50: 98, 1991.
27. Rideout, W. M., III, Coetzee, G. A., Olumi, A. F., and Jones, P. A. 5-Me-thylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science (Washington DC), 249: 1288-1290, 1990.
28. Miyaki, M., Suzuki, K., Aihara, M., and Ono, T. Misincorporation in DNA synthesis after modification of template or polymerase by MNNG, MMS and UV radiation. Mutat. Res., 107: 203-218, 1983.
29. Bos, J. L. ras oncogenes in human cancer: a review. Cancer Res., 49:4682-4689, 1989.
30. Finlay, C. A., Hinds, P. W., Tan, T-H., Eliyahu, D., Oren, M., and Levine, A. J. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol. Cell. Biol., 8: 531-539, 1988.
31. DavidofT, A. M., Kerns, B.-J.M., Iglehart, J. D., and Marks, J. R. Maintenance of p53 alterations throughout breast cancer progression. Cancer Res., 51: 2605-2610, 1991.
32. Gannon, J. V., Greaves, R., Iggo, R., and Lane, D. P. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J., 9: 1595-1602, 1990.
33. Banks, L., Matlashewski, G., and Crawford, L. Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur. J. Biochem., 159: 529-534, 1986.
34. Milner, J. Different forms of p53 detected by monoclonal antibodies in nondividing and dividing lymphocytes. Nature (Lond.), 310: 143-145, 1984.
35. Purdie, C. A., O'Grady, J., Piris, J., Wyllie, A. H., and Bird, C. C. p53 expression in colorectal tumors. Am. J. Pathol., 138: 807-813, 1991.