Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylainine to products genotoxic in an acetyltransferase-overexpressing salmonella typhimurium strain (nm2009)

Carcinogenesis

Volumn 13, Issue 6, 1992, Pages 979-985

  Yamazaki, Hiroshi ^a   Oda, Yoshimitsu ^a   Funae, Yoshihiko ^a,b   Imaoka, Susumu ^a,b   Inui, Yukiharu ^a,c   Guengerich, F Peter ^a,d   Shimada, Tsutomu ^a  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Centerfor Adult Diseases Osaka ^*  (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; ACYLTRANSFERASE; ALCOHOL; CYTOCHROME B5; CYTOCHROME P450; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; ENZYME ANTIBODY; ISONIAZID;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME INDUCTION; GENOTOXICITY; LIVER; LIVER MICROSOME; MALE; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; SALMONELLA TYPHIMURIUM; STARVATION;

ACETYLTRANSFERASES; ANIMAL; BIOTRANSFORMATION; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; HYDROXYLATION; MALE; METHYLATION; MICROSOMES, LIVER; NITROSO COMPOUNDS; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RATS, INBRED STRAINS; SALMONELLA TYPHIMURIUM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026691523     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/13.6.979     Document Type: Article

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