Synthesis, antimicrobial and antiviral activities of isotrimethoprim and some related derivatives

European Journal of Medicinal Chemistry

Volumn 27, Issue 3, 1992, Pages 251-257

  Botta, M ^a   Artico, M ^b   Massa, S ^b   Gambacorta, A ^b   Marongiu, ME ^c   Pani, A ^c   La Colla, P ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

antimicrobial agents; antiviral agents; diaminopyrimidines; trimethoprim analogues

Indexed keywords

2,4 DIAMINO 6 BENZYLPYRIMIDINE DERIVATIVE; 4 CHLORO 6 (ALPHA,ALPHA DICHLORO 4 METHOXYBENZYL) 2 METHOXYPYRIMIDINE; ANTIFUNGAL AGENT; ISOTRIMETHOPRIM; METHOTREXATE; SULFAMETHOXAZOLE; TRIMETHOPRIM; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOTOXICITY; DNA VIRUS; DRUG SYNTHESIS; ESCHERICHIA COLI; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RNA VIRUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS MITIS;

EID: 0026691450     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/0223-5234(92)90009-P     Document Type: Article

References (9)

1. 6-Alkyl- and 5,6-Dialkyl-2-methoxy-4(3H)-pyrimidinones in the Transformations of Pyrimidines. Conversion into 2-Substituted Amino- and 4-Chloro-Pyrimidine-Derivatives
2. Analysis of In Vitro Antibacterial Activities of the Combination of Trimethoprim and Sulfamethoxazole on Clinical Isolates in Japan