(E)-1,3-Dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl) xanthines: Potent and Selective Adenosine A2 Antagonists

Journal of Medicinal Chemistry

Volumn 35, Issue 12, 1992, Pages 2342-2345

  Shimada, Junichi ^a   Suzuki, Fumio ^a   Nonaka, Hiromi ^a   Ishii, Akio ^a   Ichikawa, Shunji ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIPROPYLXANTHINE DERIVATIVE; 7 METHYL 1,3 DIPROPYL 8 (3,4,5 TRIMETHOXYSTYRYL)XANTHINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; CAFFEINE; CYCLOHEXYLADENOSINE; N [2 (DIMETHYLAMINO)ETHYL] N METHYL 4 (1,3 DIPROPYLXANTHIN 8 YL)BENZENESULFONAMIDE; THEOPHYLLINE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; GUINEA PIG; HEMODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; LETTER; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION;

ADENOSINE; ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ANIMAL; CELL MEMBRANE; COMPARATIVE STUDY; CORPUS STRIATUM; GUINEA PIGS; MOLECULAR STRUCTURE; PROSENCEPHALON; RATS; RECEPTORS, PURINERGIC; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHINES;

EID: 0026690401     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00090a027     Document Type: Article

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