An arginine to histidine mutation in codon 315 of the c-erbA β thyroid hormone receptor in a kindred with generalized resistance to thyroid hormones results in a receptor with significant 3,5,3'-triiodothyronine binding activity

Journal of Clinical Endocrinology and Metabolism

Volumn 74, Issue 5, 1992, Pages 1164-1170

  Cugini, Christy D ^a,d   Leidy, John W ^a   Chertow, Bruce S ^a   Bérard, Jacques ^b   Bradley, W Edward C ^b   Menke, Jay B ^c   Hao, En Hui ^c   Usala, Stephen J ^c  

^a Marshall University School of Medicine ^*  (Italy)

^b Institut du Cancer de Montreal   (Canada)

^c EAST CAROLINA UNIVERSITY   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORYCTOLAGUS CUNICULUS;

ARGININE; COMPLEMENTARY DNA; HISTIDINE; LIOTHYRONINE; THYROID HORMONE RECEPTOR;

ADULT; ARTICLE; BINDING AFFINITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENE MUTATION; HORMONE RESISTANCE; HUMAN; MALE; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR BINDING; THYROTROPIN BLOOD LEVEL;

ADULT; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; CODON; DRUG RESISTANCE; HUMAN; MIDDLE AGE; MOLECULAR SEQUENCE DATA; MUTATION; PROTO-ONCOGENE PROTEINS; RECEPTORS, THYROID HORMONE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THYROID HORMONES; TRIIODOTHYRONINE;

EID: 0026690311     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jcem.74.5.1314846     Document Type: Article

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