Direct detection of cytomegalovirus in peripheral blood leukocytes—a review of the antigenemia assay and polymerase chain reaction

Transplantation

Volumn 54, Issue 2, 1992, Pages 193-198

  The, T H ^a   Van Der Ploeg, M ^a,b   Van Den Berg, A P ^a,b   Vlieger, A M ^a,b   Van Der Giessen, M ^a,b   Van Son, W J ^a,b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; VIRUS ANTIGEN;

BLOOD SAMPLING; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; GENE AMPLIFICATION; HUMAN; IMMUNOASSAY; IMMUNOPEROXIDASE STAINING; MONOCYTE; MORBIDITY; NEUTROPHIL; PATIENT CARE; POLYMERASE CHAIN REACTION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REVIEW; TRANSPLANTATION; VIREMIA; VIRUS DETECTION; VIRUS REPLICATION;

ANTIGENS, VIRAL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; HUMAN; LEUKOCYTES; ORGAN TRANSPLANTATION; POLYMERASE CHAIN REACTION; SUPPORT, NON-U.S. GOV'T;

EID: 0026688077     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199208000-00001     Document Type: Article

References (47)

1. Rubin RH. Infections in the patient after renal and liver trans-plantation. In: Rubin RH, Young LS, eds. Clinical approach to infections in the immunocompromised patient. 2nd ed. New York: Plenum, 1988: 557.
2. Van Son WJ, The TH. Cytomegalovirus infection after transplan-tation: an update. Transplant Int 1990; 2:147.
3. Richardson WP, Colvin RB, Cheeseman SH, et al. Glomerulopathy associated with cytomegalovirus viremia in renal allografts. N Engl J Med 1981; 305: 57.
4. Grattan MT, Moreno-Abral CE, Starnes VA, Oyer PE, Stinson EB, Shumway NE. Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosis. JAMA 1989; 261: 3561.
5. Keenan RJ, Lega ME, Dummer JS, et al. Cytomegalovirus serologic status and postoperative infection correlated with risk of developing chronic rejection after pulmonary transplantation. Transplantation 1991; 51: 433.
6. Van der Bij W, Van Dijk RB, Van Son WJ, et al. Antigen test for early diagnosis of active cytomegalovirus infection in heart transplant patients. J Heart Transplant 1988; 7: 106.
7. Jiwa NM, Van Gemert GW, Raap AK, et al. Rapid detection of human cytomegalovirus DNA in peripheral blood leukocytes of viremic transplant recipients by the polymerase chain reaction. Transplantation 1989; 48: 72.
8. Cassol SA, Poon MC, Pal R, et al. Primer-mediated enzymatic amplification of cytomegalovirus (CMV) DNA: application to the early diagnosis of CMV infection in marrow transplant recipients. J Clin Invest 1989; 83: 1109.
9. Olive DM, Simsek M, Al-Mufti S. Polymerase chain reaction assay for detection of human cytomegalovirus. J Clin Microbiol 1989; 27: 1238.
10. Mach M, Stamminger Th, Jahn G. Human cytomegalovirus: recent aspects from molecular biology. J Gen Virol 1989; 70: 3117.
11. Grefte JMM, Van der Giessen M, Van der Gun BTF, Van Son WJ, The TH. The predominant viral antigen present in peripheral blood leukocytes during an active CMV infection is the lower matrix protein pp 65. In: Landini MP, ed. Progress in cytomegalovirus research. Amsterdam: Elsevier, 1991: 233.
12. Van der Bij W, Schirm J, Torensma R, Van Son WJ, Tegzess AM, The TH. Comparison of viremia and antigenemia for detection of cytomegalovirus in blood. J Clin Microbiol 1988; 26: 2531.
13. Revello MG, Percival E, Zavattoni M, Parea M, Grossi P, Gerna G. Detection of human cytomegalovirus immediate early antigen in leukocytes as a marker of viremia in immunocompromised patients. J Med Virol 1989; 29: 88.
14. Bein G, Bitsch A, Hoyer J, Kirchner H. The detection of human cytomegalovirus immediate early antigen in peripheral blood leucocytes. J Immunol Methods 1991; 137: 175.
15. Saiki RK, Scharf S, Faloona F, et al. Enzymatic amplification of 0-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 1985; 230:1350.
16. Persing DH. Polymerase chain reaction: trencheB to benches. J Clin Microbiol 1991; 29:1281.
17. Shibata D, Martin WJ, Appleman MD, Causey DM, Leedom JM, Arnheim N. Detection of cytomegalovirus DNA in peripheral blood of patients infected with human immunodefiency virus. J Infect Dis 1988; 158:1185.
18. Pritchett RF. DNA nucleotide sequence heterogeneity between the Towne and AD169 strains of cytomegalovirus. J Virol 1980; 36: 152.
19. Chou S, Dennison KM. Analysis of interstrain variation in cyto-megalovirus glycoprotein B sequences encoding neutralization-related epitopes. J Infect Dis 1991; 163:1229.
20. Stanier P, Taylor DL, Kitchen AD, Wales N, Tryhorn Y, Tyms AS. Persistence of cytomegalovirus in mononuclear cells in peripheral blood from blood donors. Br Med J 1989; 299: 897.
21. Buffone GJ, Hine E, Demmler GJ. Detection of mRNA from the immediate early gene of human cytomegalovirus in infected cells by in vitro amplification. Mol Cell Probes 1990; 4:143.
22. Rowley AH, Wolinsky SM, Sambol SP, Barkholt L, Ehrnst A, Andersson JP. Rapid detection of cytomegalovirus DNA and RNA in blood of renal transplant patients by in vitro enzymatic amplification. Transplantation 1991; 51:1028.
23. Van den Berg AP, Van der Bij W, Van Son WJ, et al. Cytomeg-alovirus antigenemia as a useful marker of symptomatic cytomegalovirus infection after renal transplantation: a report of 130 consecutive patients. Transplantation 1989; 48: 991.
24. Boland GJ, De Gast GC, Hene RJ, et al. Early detection of active cytomegalovirus (CMV) infection after heart and kidney transplantation by testing for immediate early antigenemia and influence of cellular immunity on the occurrence of CMV infection. J Clin Microbiol 1990; 28: 2069.
25. Van den Berg AP, Klompmaker IJ, Haagsma EB, et al. Antigene-mia in the diagnosis and monitoring of active CMV infection after liver transplantation. J Infect Dis 1991; 164: 265.
26. Einsele H, Steidle M, Vallbracht A, Saal JG, Ehninger G, Muller CA. Early occurrence of human cytomegalovirus infection after bone marrow transplantation as demonstrated by the polymerase chain reaction technique. Blood 1991; 77: 1104.
27. Gerna G, Zipeto D, Parea M, et al. Monitoring of human cytomeg-alovirus infections and ganciclovir treatment in heart transplant recipients by determination of viremia, antigenemia and DNAe-mia. J Infect Dis 1991, 164: 488.
28. Van den Berg AP, Van Son WJ, Jiwa NM, et al. Recent advances in the diagnosis of active CMV infection after organ transplantation. Transplant Proc 1990; 22: 226-8.
29. Emanuel D, Cunningham I, Jules-ElyBee K, et al. Cytomegalovirus pneumonia after bone marrow transplantation successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin. Ann Intern Med 1988; 109: 777.
30. Reed EC, Bowden RA, Dandliker PS, Lilleby KE, Meyers JD. Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patients with bone marrow transplants. Ann Intern Med 1988; 109: 783.
31. Shepp DH, Dandliker PS, de Miranda P, et al. Activity of 9-[2-hydroxy-l-(hydroxymethyl)ethoxy-methyl]guanine in the treatment of cytomegalovirus pneumonia. Ann Intern Med 1985; 103: 368.
32. Enrice A, Jordan MC, Chace BA, Fletcher C, Chinnock BJ, Balfour HH Jr. Ganciclovir treatment of cytomegalovirus disease in transplant recipients and other immunocompromised hosts. JAMA 1987; 257: 3082.
33. Harbison MA, De Girolani PC, Jenkins RL, Hammer SM. Ganci-clovir therapy of severe cytomegalovirus infection in solid-organ transplant recipients. Transplantation 1988; 46: 82.
34. Dunn DL, Mayoral JL, Gillingham KJ, Loeffler CM, Brayman KL, Kramer MA. Treatment of invasive cytomegalovirus disease in solid organ transplant patients with ganciclovir. Transplantation 1991; 51: 98.
35. Schmidt GM, Horak DA, Niland JC, et al. A randomized, controlled trial of prophylactic ganciclovir for cytomegalovirus pulmonary infection in recipients of allogeneic bone marrow transplants. N Engl J Med 1991; 324:1005.
36. Goodrich JM, Mori M, GleaveB CA, et al. Early treatment with ganciclovir to prevent cytomegalovirus disease after allogeneic bone marrow transplantation. N Engl J Med 1991; 325: 1601.
37. Rubin RH. Pre-emptive therapy in immunocompromised hosts. N Engl J Med 1991; 324: 1057.
38. Hibberd PI, Tolkoff-Rubin NE, Cosimi AB, et al. Symptomatic cytomegalovirus disease in the cytomegalovirus antibody-sero-positive renal transplant recipient treated with OKT3. Transplantation 1992; 53: 68.
39. Burns KD, Johnson-Whittaker L, Couture RA, Eidus L, Garber G. Successful treatment of renal allograft rejection in the presence of cytomegalovirus disease. Am J Nephrol 1990; 10: 162.
40. De Koning J, Van Dorp WT, Van Es LA, Van't Wout JW, Van der Woude FJ. Ganciclovir effectively treats cytomegalovirus disease after solid organ transplantation, even during rejection treatment. Nephrol Dial Transplant 1992; 7: 350.
41. Van den Berg AP, Tegzess AM, Scholten-Sampson A, Van der Giessen M, The TH, Van Son WJ. Quo vadis? The clinical dilemma of simultaneous cytomegalovirus infection and steroid-resistant rejection. Transplantation 1991; 52: 1081.
42. Revello MG, Zavattoni M, Percivale E, Grossi P, Gerna G. Corre-lation between immunofluorescent detection of human cytomegalovirus immediate early antigen in polymorphonuclear leukocytes and viremia. J Infect Dis 1989; 160: 159.
43. Van den Berg AP, Tegzess AM, Scholten-Sampson A, et al. Cyto-megalovirus antigenemia is useful for monitoring antiviral therapy. Transplant Int 1992; 5: 101.
44. Faulds D, Heel RC. Ganciclovir: a review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections. Drugs 1990; 39: 597.
45. Einsele H, Ehninger G, Steidle M, et al. Polymerase chain reaction to evaluate antiviral therapy for cytomegalovirus disease. Lancet 1991; 338: 1170.
46. Van der Giessen M, Van den Berg AP, Van der Bij W, Postma S, Van Son WJ, The TH. Quantitative measurement of CMV-specific IgG-and IgM-antibodies in relation to CMV antigenemia and disease activity in kidney transplantation with active CMV infection. Clin Exp Immunol 1990; 80: 56.
47. Van der Bij W, Van Son WJ, Van den Berg AP, Tegzess AM, Torensma R, The TH. Cytomegalovirus antigenemia: rapid diagnosis and relationship with CMV-associated clinical syndromes in renal allograft recipients. Transplant Proc 1989; 21: 2061.