MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates

Cell

Volumn 70, Issue 5, 1992, Pages 791-801

  Li, Jianxun ^a   Aderem, Alan ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; BACTERIUM LIPOPOLYSACCHARIDE; CALMODULIN; PROTEIN KINASE C; SOMATOMEDIN B RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CYTOSKELETON; DNA SEQUENCE; ENZYME SUBSTRATE; GENETIC TRANSFECTION; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MITOGENESIS; MOLECULAR CLONING; MOUSE; NEUROSECRETION; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; RABBIT;

ACTINS; AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BINDING SITES; CALMODULIN; CELL LINE; CLONING, MOLECULAR; COMPARATIVE STUDY; CYTOSKELETON; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; PROTEIN KINASE C; PROTEINS; RABBITS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

BACTERIA (MICROORGANISMS); ORYCTOLAGUS CUNICULUS;

EID: 0026686927     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(92)90312-Z     Document Type: Article

References (51)

1. Modulation of macrophage arachidonic acid metabolism by bacterial lipopolysaccharides; the role of protein myristoylation and calcium transients
2. Calcium ionophore synergizes with bacterial lipopolysaccharides in activating macrophage arachidonic acid metabolism
3. A selective defect in arachidonic acid release from macrophage membranes in high potassium media
4. Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites
5. Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins
6. Stimulus-dependent myristoylation of a major substrate for protein kinase C
7. The 87k protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization
8. Purification and characterization of a brain-specific protein kinase C substrate, neurogranin (p17)
9. T-independent and T-dependent steps in the murine B cell response to antiimmunoglobulin
10. Protein kinase C-stimulated phosphorylation in vitro of a Mr 80,000 protein phosphorylated in response to phorbol esters and growth factors in intact fibroblasts
11. Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog
12. Innate immunity
13. The ras superfamily of small GTP-binding proteins
14. Molecular cloning and characterization of the acidic 80-kd protein kinase C substrate from rat brain
15. Internal protein sequence analysis: enzymatic digestion for less than 10 μg of protein bound to polyvinilidene difluoride or nitrocellulose membranes
16. GAP-43 — what does it do in the growth cone
17. Myristoylated and nonmyristoylated forms of a protein are phosphorylated by protein kinase C
18. Characterization of the phosphorylation sites in the chicken and bovine myristoylated alanine-rich C kinase substrate protein, a prominent cellular substrate for protein kinase C
19. Molecular cloning, sequence, and expression of a cDNA encoding the chicken myristoylated alanine-rich C kinase substrate (MARCKS)
20. Phosphorylation-regulated calmodulin binding to a prominent cellular substrate for protein kinase C
21. Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain
22. Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide
23. The human myristoylated alanine-rich C kinase substrate (MARCKS) gene (MACS)
24. MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin
25. Myristoylation of an inhibitory GTP-binding protein α subunit is essential for its membrane attachment
26. A protein modulator stimulates C kinase-dependent phosphorylation of a 90K substrate in synaptic membranes
27. Selective conservation of GAP-43 structure in vertebrate evolution
28. Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration
29. Cloning and sequence analysis of the cation-independent mannose 6-phosphate receptor
30. The response of histiocytes and macrophages in the lungs of rabbits injected with Freund's adjuvant
31. G-protein α-subunit expression, myristoylation, and membrane association in COS cells
32. How calmodulin binds its targets: sequence independent recognition of amphiphilic alphahelices
33. Biochemistry of endotoxins
34. v-src to plasma membranes: evidence of a myristyl-src receptor
35. Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src
36. Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages
37. Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia
38. Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells
39. Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein
40. Cloning and molecular characterization of the murine macrophage “68-kd” protein kinase C substrate and its regulation by bacterial lipopolysaccharide
41. Reorganization of microfilaments in macrophages after LPS stimulation
42. Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43
43. Molecular cloning, characterization, and expression of a cDNA encoding the “80- to 87-kd” myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C
44. Tumor necrosis factor α modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate
45. Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane
46. Myristoyl CoA: protein N-myristoyltransferase activities from rat liver and yeast possess overlapping yet distinet peptide substrate specificities
47. The biology and enzymology of eukaryotic protein acylation
48. A mouse brain cDNA encodes a novel protein with the protein kinase C phosphorylation site domain common to MARCKS
49. ick
50. Calcium/phospholipid regulates phosphorylation of a Mr “87k” substrate protein in brain synaptosomes