New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of β-lactam synthon method

Tetrahedron

Volumn 48, Issue 34, 1992, Pages 6985-7012

  Ojima, Iwao ^a   Habus, Ivan ^a   Zhao, Mangzhu ^a   Zucco, Martine ^a   Park, Young Hoon ^a   Sun, Chung Ming ^a   Brigaud, Thierry ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACCATIN III DERIVATIVE; PACLITAXEL; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0026686518     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)91210-4     Document Type: Article

References (58)

1. TAXANE DITERPENE SYNTHESIS STRATEGIES. A REVIEW
2. Relationships between the structure of taxol analogs and their antimitotic activity
3. LIPASE-CATALYZED KINETIC RESOLUTION OF ALCOHOLS VIA CHLOROACETATE ESTERS: (−)-(1R,2S)-trans-2-PHENYLCYCLOHEXANOL AND (+)-(1S,2R)-trans-2-PHENYLCYCLOHEXANOL
4. The triisopropylsilyl group as a hydroxyl-protecting function
5. Nuclear Overhauser Effect Spectroscopy (NOESY) and Dihedral Angle Measurements in the Determination of the Conformation of Taxol in Solution
6. Optical Resolution and Configuration of cis-β-Phenylglycidic Acid
7. An expeditious synthesis of the (2R,3S)- and (2S,3R)-3-amino-2-hydroxycarboxylic acids, the key components of a renin inhibitor and bestatin, from (S)- and (R)-phenylalanine.
8. Antileukemic alkaloids from Taxus wallichiana Zucc