Kinetic analysis of hepatobiliary transport of vincristine in perfused rat liver. Possible roles of P-glycoprotein in biliary excretion of vincristine

Journal of Hepatology

Volumn 16, Issue 1-2, 1992, Pages 77-88

  Watanabe, Tohru ^a   Miyauchi, Seiji ^a   Sawada, Yasufumi ^a   Iga, Tatsuji ^a   Hanano, Manabu ^a   Inaba, Makoto ^b   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Foundation for Promotion of Cancer Research   (Japan)

Author keywords

Biliary excretion; Multidrug resistance; P glycoprotein; Perfused rat liver; Verapamil; Vincristine

Indexed keywords

TAUROCHOLIC ACID; VERAPAMIL; VINCRISTINE; VINCRISTINE SULFATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; DRUG RESISTANCE; LIVER PERFUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; BILE DUCTS; BIOLOGICAL TRANSPORT; CHROMATOGRAPHY, THIN LAYER; CYTOSOL; DRUG RESISTANCE; IN VITRO; KINETICS; LIVER; MALE; MEMBRANE GLYCOPROTEINS; P-GLYCOPROTEIN; PERFUSION; RATS; RATS, WISTAR; VERAPAMIL; VINCRISTINE;

EID: 0026683912     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(05)80098-4     Document Type: Article

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