Continuous intrathecal opioid treatment abolishes the regulatory effects of magnesium and guanine nucleotides on mu opioid receptor binding in rat spinal membranes

Journal of Pharmacology and Experimental Therapeutics

Volumn 262, Issue 1, 1992, Pages 317-326

  Wong, C S ^a   Su, Y F ^a   Watkins, W D ^a   Chang, K J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 METHIONINOL SULFOXIDE]; GUANINE NUCLEOTIDE; GUANOSINE DIPHOSPHATE; GUANYLYLIMIDODIPHOSPHATE; LIGAND; MAGNESIUM ION; MORPHICEPTIN[3 (N METHYLPHENYLALANINE) 4 DEXTRO PROLINAMIDE]; MORPHINE SULFATE; MU OPIATE RECEPTOR; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NALOXONE; PERTUSSIS TOXIN; SODIUM ION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING COMPETITION; BINDING SITE; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG TOLERANCE; INTRATHECAL DRUG ADMINISTRATION; LIGAND BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; SPINAL CORD;

ANIMAL; CELL MEMBRANE; DRUG TOLERANCE; ENDORPHINS; FK 33-824; GUANYLYL IMIDODIPHOSPHATE; MAGNESIUM; MALE; MORPHINE; NALOXONE; RATS; RATS, INBRED STRAINS; RECEPTORS, OPIOID; RECEPTORS, OPIOID, MU; SPINAL CORD; SUPPORT, U.S. GOV'T, P.H.S.; VIRULENCE FACTORS, BORDETELLA;

EID: 0026681670     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)