Mobilization of T lymphocytes following cardiac transplantation: Evidence that CD4-positive cells are required for cytotoxic T lymphocyte activation, inflammatory endothelial development, graft infiltration, and acute allograft rejection

Transplantation

Volumn 53, Issue 4, 1992, Pages 849-857

  Bishop, D Keith ^a   Shelby, Jane ^a   Eichwald, Ernst J ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OKT 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DILUTION; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HELPER CELL; IMMUNOHISTOLOGY; LYMPHOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VASCULAR ENDOTHELIUM;

ANIMAL; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ENDOTHELIUM, VASCULAR; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; ISOANTIGENS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER; TRANSPLANTATION, HOMOLOGOUS;

EID: 0026680680     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199204000-00027     Document Type: Article

References (40)

1. Bishop DK, Orosz CG. Limiting dilution analysis for alloreactive, TCGF-secretingT cells: LDA methods that discriminate between unstimulated precursor T cells and in vivo alloactivated T cells. Transplantation 1989; 47: 671.
2. Orosz CG, Horstemeyer B, Zinn NE, Bishop DK. Development and evaluation of an LDA technique that can discriminate in vivo alloactivated CTL from their naive CTL precursors. Transplantation 1989; 47: 189.
3. Corry RJ, Winn HS, Russell PS. Primarily vascularized allografts of hearts in mice. Transplantation 1973; 16: 343.
4. Glasebrook AL, Fitch FW. Alloreactive cloned T cell lines: interactions between cloned amplifier and cytolytic T cell lines. J Exp Med 1980; 151: 876.
5. Farrar J, Fuller-Farrar J, Simon P, Hilfiker M, Stadler B, Farrar W. Thymoma production of T cell growth factor (interleukin 2). J Immunol 1980; 125: 2555.
6. Ryser JE, MacDonald HR. Limiting dilution analysis of alloantigen-reactive T lymphocytes: I. Comparison of precursor frequencies for proliferative and cytolytic responses. J Immunol 1979; 122: 1691.
7. MacDonald HR, Cerottini J-C, Ryser J-E, et al. Quantitation and cloning of cytolytic T lymphocytes and their precursors. Immunol Rev 1980; 51: 93.
8. Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies: I. Data analysis. J Immunol 1981; 126: 1614.
9. Orosz CG, Zinn NE, Sirinek L, Ferguson RM. In vivo mechanisms of alloreactivity: I. Frequency of donor-reactive cytotoxic T lymphocytes in sponge matrix allografts. Transplantation 1986; 41: 75.
10. Leppink DM, Bishop DK, Sedmak DD, et al. Inducible expression of an endothelial cell antigen on murine myocardial vasculature in association with interstitial cellular infiltration. Transplantation 1989; 48: 874.
11. Nakache M, Berg EL, Streeter PR, Butcher EC. The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes. Nature 1989; 337: 179.
12. Streeter PR, Rouse BTN, Butcher EC. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J Cell Biol 1988; 107: 1853.
13. Larsson E. Mechanisms of T cell activation: II. Antigen and lectindependent acquisition of responsiveness to TCGF is a non-mitogenic active response of resting T cells. J Immunol 1981; 126: 1323.
14. Meuer S, Hussey R, Cantrell D, et al. Triggering the T3-Ti antigenreceptor complex results in clonal T cell proliferation through an interleukin 2-dependent autocrine pathway. Proc Natl Acad Sci USA 1984; 81: 1509.
15. Gillis S, Gillis A, Henney C. Monoclonal antibody directed against interleukin 2: I. Inhibition of T lymphocyte mitogenesis and the in vitro differentiation of alloreactive cytolytic T cells. J Exp Med 1981; 154: 422.
16. Matzinger P, Bevan MJ. Why do so many lymphocytes respond to major histocompatibility antigens? Cell Immunol 1977; 29: 1.
17. Bishop DK, Ferguson RM, Orosz CG. Differential distribution of antigen specific helper T cells and cytotoxic T cells after antigenic stimulation in vivo: a functional study using limiting dilution analysis. J Immunol 1990; 144: 1153.
18. Powell TJ, Streilein JW. Neonatal tolerance induction by class II alloantigen8 activates IL-4-secreting, tolerogen-responsive T cells. J Immunol 1990; 144: 854.
19. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell: IV. Th2 clones secrete a factor that inhibits cytokine production by Thl clones. J Exp Med 1898; 170: 2081.
20. Bishop DK, Shelby J, Eichwald EJ. Functional analysis of donorreactive T cells infiltrating heterotopic cardiac transplants: effect of anti-CD4 monoclonal antibodies in vivo. Transplant Proc 1991; 23: 287.
21. Berg EL, Goldstein LA, Jutila MA, et al. Homing receptors and vascular addressins: cell adhesion molecules that direct lymphocyte traffic. Immunol Rev 1989; 108: 5.
22. Jalkanen S, Steere AC, Fox RI, Butcher EC. A distinct endothelial cell recognition system that controls lymphocyte traffic into inflamed synovium. Science 1986; 233: 556.
23. Steinmuller D. Which T cells mediate allograft rejection? Transplantation 1985; 40: 229.
24. Mason DW, Morris PJ. Effector mechanisms in allograft rejection. Annu Rev Immunol 1986; 4: 119.
25. Loveland BE, Hogarth PM, Ceredig R, McKenzie IFC. Cells mediating graft rejection in the mouse: I. Lyt-1 cells mediate skin graft rejection. J Exp Med 1981; 153: 1044.
26. LeFrancois L, Bevan MJ. A reexamination of the role of Lyt-2positive T cells in murine skin graft rejection. J Exp Med 1984; 159: 57.
27. Lafferty KJ, Prowse SJ, Simeonovic CJ, Warren HS. Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. Annu Rev Immunol 1983; 1: 143.
28. Rosenberg AS, Mizuochi T, Singer A. Analysis of T-cell subsets in rejection of Kb mutant skin allografts differing at class I MHC. Nature 1986; 322: 829.
29. Cobbold SP, Jayasuriya A, Nash A, Prospero TD, Waldmann H. Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature 1984; 312: 548.
30. Cobbold S, Waldmann H. Skin allograft rejection by L3T4* and Lyt-2* T cell subsets. Transplantation 1986; 41: 634.
31. Hao L, Wang Y, Gill RG, Lafferty KJ. Role of the L3T4+ T cell in allograft rejection. J Immunol 1987; 139: 4022.
32. McCarthy SA, Singer A. Recognition of MHC class I allodeterminants regulates the generation of MHC class II-specific CTL. J Immunol 1986; 137: 3087.
33. Okada M, Henney CS. The differentiation of cytotoxic T cells in vitro: III. The role of helper T cells and their products in the differentiation of cytotoxic cells from "memory" cell populations. J Immunol 1980; 125: 850.
34. Tyler JD, Galli SJ, Snider ME, Dvorak AM, Steinmuller D. Cloned Lyt-2+ cytolytic T lymphocytes destroy allogeneic tissue in vivo. J Exp Med 1984; 159: 234.
35. Steinmuller D, Snider ME, Noble RL, Waldschmidt TJ. Dissociation of tissue destruction induced by cytotoxic T cells in vivo and cytotoxicity as measured in vitro. Transplantation 1990; 50: 663.
36. Hanto DW, Widmer MB, Simmons RL. Mediation of cellular recruitment in vivo by functionally distinct T cell clones. Transplantation 1986; 42: 168.
37. Pober JS. Cytokine-mediated activation of vascular endothelium: physiology and pathology. Am J Pathol 1988; 133: 426.
38. Issekutz TB, Stoltz JM, Meide P. Lymphocyte recruitment in delayed-type hypersensitivity: the role of IFN-7. J Immunol 1988; 140: 2989.
39. Fong TAT, Mosmann TR. Alloreactive murine CD8* T cell clones secrete the Thl pattern of cytokines. J Immunol 1990; 144:1744.
40. Reem GH, Yeh N-H. Interleukin 2 regulates expression of its receptor and synthesis of gamma interferon by human T lymphocytes. Science 1984; 225: 429.