Preparation of submicron drug particles in lecithin-stabilized o/w emulsions I. Model studies of the precipitation of cholesteryl acetate

International Journal of Pharmaceutics

Volumn 88, Issue 1-3, 1992, Pages 53-62

  Sjöström, Brita ^a   Bergenståhl, Björn ^a  

^a INSTITUTE FOR SURFACE CHEMISTRY   (Sweden)

Author keywords

Bile salt; Cholesteryl acetate; Emulsion; Lecithin; Precipitation; Submicron particles; Suspension

Indexed keywords

CHOLESTEROL ACETATE; CHOLESTEROL DERIVATIVE; EMULSIFYING AGENT; EPIKURON; GLYCOCHOLIC ACID; LIPOSOME; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; EMULSION; PARTICLE SIZE; PRIORITY JOURNAL;

EID: 0026679872     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(92)90303-J     Document Type: Article

References (40)

1. Phase equilibria in four lysophosphatidylcholine/water systems. Exceptional behaviour of 1-palmitoyl-glycero-phosphocholine
2. Phase diagrams of mixed soybean phospholipids
3. Surface forces in emulsions
4. Parenteral emulsions for drug delivery
5. The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin
6. Emulsion systems for the delivery of drugs by the parenteral route
7. Medical and pharmaceutical applications of emulsions
8. Lipid emulsions as drug delivery systems
9. Drug Solubilization in surfactant systems
10. Influence of phase equilibria and properties of emulsions
11. Liquid crystals - the formula for emulsions
12. The effect of stablishing agents on the organ distribution of lipid emulsions
13. Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers
14. The solubilization of some steroids by phosphatidylcholine and lysophosphatidylcholine
15. Liquid crystallinity in systems of magnesium and calcium surfactants
16. Design and characterization of a submicronized o/w emulsion of diazepam for parenteral use
17. 31P NMR, and X-ray diffraction
18. Interactions between neutral phospholipid bilayer membranes
19. Application of liposomes to the delivery of antifungal agents
20. The effect of poloxamer 407 on liposome stability and targeting to bone marrow; comparison with polystyrene microspheres
21. Medicinal emulsions
22. Aspects of dispersed phase disruption
23. The use of oil-in-water emulsions as a vehicle for parenteral drug administration
24. Interacting phospholipid bilayer: Measured forces and induced structural changes
25. The function of phospholipids of soybean lecithin in emulsions
26. Fate and behavior of liposomes in vivo: A review of controlling factors
27. Parenteral emulsions as drug carrier systems
28. A method for the preparation of submicron particles of sparingly water soluble drugs by precipitation in o/w-emulsions I. The influence of emulsification and surfactant concentration
29. A method for the preparation of submicron particles of sparingly water soluble drugs by precipitation in o/w-emulsions II. The influence of the emulsifier, the solvent and the drug substance
30. Phase equilibria and structure of dry and hydrated egg lecithin
31. Lyotropic paracrystalline phases obtained with ternary and quaternnary systems of amphiphilic substances in water studies on aqueous systems of lecithin bile salt and cholesterol
32. Ternary and quaternary aqueous systems containing bile salt, lecithin, and cholesterol
33. The binary system soybean phosphatidylinositol-water
34. Stability of oil-in-water emulsions with crystals in the disperse phase
35. Diazepam in emulsion form for intravenous usage
36. Formation of emulsions
37. Overview of emulsion and foam stability
38. Liposomes as a drug delivery system
39. Liposomes in the diagnosis and treatment of cancer
40. Beitrag zur Strukturaufklärung eines arzneistoffhaltigen hochkonzentrierten Tensidsstems und ausgewählter Verdünnungen