The comparative effects of big endothelin-1, endothelin-1, and endothelin-3 in the human fetal-placental circulation

American Journal of Obstetrics and Gynecology

Volumn 167, Issue 6, 1992, Pages 1651-1656

  Myatt, Leslie ^a   Brewer, Anthony S ^a   Brockman, Diane E ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Endothelin; fetus; placenta; vasoconstriction

Indexed keywords

BIG ENDOTHELIN 1; ENDOTHELIN 1; ENDOTHELIN 3; ENDOTHELIN CONVERTING ENZYME; PHOSPHORAMIDON;

ARTICLE; FETUS; HUMAN; HUMAN TISSUE; PLACENTA CIRCULATION; PRIORITY JOURNAL; VASOCONSTRICTION;

BLOOD CIRCULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELINS; FEMALE; FETUS; HUMAN; PERFUSION; PLACENTA; PREGNANCY; PRESSURE; PROTEIN PRECURSORS; REGIONAL BLOOD FLOW; SUPPORT, U.S. GOV'T, P.H.S.; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0026676640     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/0002-9378(92)91756-Z     Document Type: Article

References (15)

1. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
2. Endothelin induces two types of contraction of rat uterus: phasic contractions by way of voltage-dependent calcium channels and developing contractions through a second type of calcium channel
3. Pituitary site of action of endothelin selective inhibition of prolactin release in vitro
4. Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy
5. One of the endothelin gene family endothelin 3 gene is expressed in the placenta
6. Endothelin-1 induced vasoconstriction is not mediated via thromboxane release and action in the human fetal-placental circulation
7. Endothelin receptors in human placenta: relationship to vascular resistance and thromboxane release
8. Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation
9. Endothelin: release by and potent constrictor effect on the fetal vessels of human perfused placental lobules
10. Specific receptors for endothelin in membranes from human placenta characterization and use in a binding assay
11. 125I] endothelin-1 binding sites in human fetal placental vessels
12. The effect of the components of the renin-angiotensin system on the isolated perfused human placental cotyledon
13. Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells
14. Pulsatile release of endothelin by the perfused human placental [Abstract]
15. Immunoreactive endothelin concentrations in maternal and fetal blood