-
2
-
-
0021326738
-
The preclinical new drug research program of the National Cancer Institute
-
(1984)
Cancer Treat Rep
, vol.68
, pp. 63-76
-
-
Driscoll1
-
5
-
-
0024578841
-
New soluble formazan assay for HIV-1 cytopathic effects: Application to high-flux screening of synthetic and natural products for AIDS-antiviral activity
-
(1989)
J Nat Cancer Inst
, vol.81
, pp. 577-586
-
-
Weislow1
Kiser2
Fine3
-
7
-
-
0019598765
-
Computer-aided selection of compounds for antitumor screening: Validation of a statistical-heuristic method
-
(1981)
J Chem Inf Comput Sci
, vol.21
, pp. 123-190
-
-
Hodes1
-
13
-
-
0024312538
-
Display and analysis of patterns of differential activity of drugs against human tumor cell lines: Development of mean graph and COMPARE Algorithm
-
(1989)
J Nat Cancer Inst
, vol.81
, pp. 1088-1092
-
-
Paull1
Shoemaker2
Hodes3
-
14
-
-
0026069885
-
Halichondrin B and Homohaichondrin B, marine natural products binding in the vinca domain of tubulin: Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data
-
(1991)
J Biol Chem
, vol.266
, pp. 15882-15889
-
-
Bai1
Paull2
Herald3
-
16
-
-
0025064889
-
Pharmacokinetics of 2-F-ara-A (9-B-D-Arabinofuranosyl-2-fluoroadenine) in cancer patients during the phase I clinical investigation of fludarabine monophosphate
-
(suppl 8)
-
(1990)
Semin Oncol
, vol.17
, pp. 18-32
-
-
Malspeis1
Grever2
Staubus3
-
20
-
-
0018952812
-
Metabolism and chemotherapeutic activity of 9-B-D-Arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase
-
(1980)
Cancer Res
, vol.40
, pp. 3610-3615
-
-
Brockman1
Cheng2
Schabel3
-
22
-
-
84912849080
-
-
Grever MR, Greishaber CK: Toxicology by Organ System, Holland JF, Frei E, Bast RC, et al (eds): in Cancer Medicine (ed 3). Philadelphia, PA, Lea and Febiger (in press)
-
-
-
-
26
-
-
0026744688
-
Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development
-
(1992)
J Pharm Sci
, vol.81
, pp. 605-610
-
-
Peck1
Barr2
Benet3
-
31
-
-
0025129894
-
An early phase II study of CPT-11: A new derivative of camptothecin, for the treatment of leukemia and lymphoma
-
(1990)
J Clin Oncol
, vol.8
, pp. 1907-1912
-
-
Ohno1
Okada2
Masoaka3
-
32
-
-
0024358188
-
DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
-
(1989)
Science
, vol.246
, pp. 1046-1048
-
-
Giovanella1
Stehlin2
Wall3
-
36
-
-
0024502202
-
Preclinical antitumor activity of an a-picoline derivative, penclomidine (NSC 338720), on human and murine tumors
-
(1989)
Cancer Res
, vol.49
, pp. 1909-1915
-
-
Plowman1
Harrison2
Dykes3
-
37
-
-
84912850427
-
Temozolomide (CCRG 81045; M&B 39831; NSC 362856): A new oral cytotoxic agent with activity against melanoma, mycosis fungoides, and high-grade glioma
-
(abstr 1267)
-
(1992)
Proc Am Assoc Cancer Res
, vol.33
, pp. 212
-
-
O'Reilly1
Newlands2
Stevens3
-
41
-
-
0025204095
-
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
-
(1990)
Nature
, vol.348
, pp. 555-557
-
-
Ingber1
Fujita2
Kishimoto3
-
42
-
-
0026735864
-
Benzoquinonoid ansamycins possess selective tumoricidal activity unrelated to src kinase inhibition
-
(1992)
Cancer Res
, vol.52
, pp. 1721-1728
-
-
Whitesell1
Shifrin2
Schwab3
-
43
-
-
0024992935
-
Design, activity, and 2.8 a crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
-
(1990)
Science
, vol.249
, pp. 527-533
-
-
Erickson1
Neidhart2
VanDrie3
-
44
-
-
0022859356
-
Overlapping cDNA clones define the complete coding region for the p210 (c-abl) gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 9768-9772
-
-
Mes-Masson1
McLaughlin2
Daley3
-
45
-
-
0025822797
-
Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene
-
(1991)
Mol Cell Biol
, vol.11
, pp. 4710-4716
-
-
Kelliher1
Knott2
McLaughlin3
-
46
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of BCR-ABL oncogene products
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo1
Pendergast2
Muller3
-
47
-
-
0025766195
-
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner
-
(1991)
Cell
, vol.66
, pp. 161-171
-
-
Pendergast1
Muller2
Havlik3
-
49
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P210 (BCR-ABL) gene of the Philadelphia chromosome
-
(1990)
Science
, vol.247
, pp. 824-829
-
-
Daley1
Van Etten2
Baltimore3
-
51
-
-
84912885474
-
O6-Methylguanine DNA methyltransferase (MGMT) mRNA levels and in vitro sensitivity of human tumor cell lines to alkylating agents
-
(abstr 2407)
-
(1992)
Proc Am Assoc Cancer Res
, vol.33
, pp. 403
-
-
Shoemaker1
Smythe2
Lin3
|