Fluoxetine modulates G protein αs, αq and α12 subunit mRNA expression in rat brain

European Journal of Pharmacology: Molecular Pharmacology

Volumn 227, Issue 2, 1992, Pages 233-237

  Lesch, K Peter ^a   Hough, Christopher J ^a   Aulakh, Charanjit S ^a   Wolozin, Benjamin L ^a   Tolliver, Teresa J ^a   Hill, James L ^a   Akiyoshi, Jotaro ^a   Chuang, De Maw ^a   Murphy, Dennis L ^a  

^a Laboratory of Clinical Science   (United States)

Author keywords

Fluoxetine; G proteins; mRNA expression; Polymerase chain reaction

Indexed keywords

FLUOXETINE; GTP BINDING PROTEINS; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; RIBONUCLEASE; COMPLEMENTARY DNA; PROTEIN SUBUNIT; RNA DIRECTED DNA POLYMERASE;

ANIMAL; ARTICLE; BIOSYNTHESIS; BRAIN; BRAIN CORTEX; CORPUS STRIATUM; DRUG EFFECT; GENE EXPRESSION; GENETICS; MALE; METABOLISM; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; RAT; RAT STRAIN; RNA TRANSLATION; ANIMAL TISSUE; BRAIN REGION; CONTROLLED STUDY; FRONTAL CORTEX; MESENCEPHALON; NEOSTRIATUM; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMAL; BLOTTING, NORTHERN; BRAIN; CEREBRAL CORTEX; CORPUS STRIATUM; FLUOXETINE; GENE EXPRESSION; GTP-BINDING PROTEINS; MALE; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RIBONUCLEASES; RNA, MESSENGER; TRANSLATION, GENETIC;

EID: 0026673358     PISSN: 09224106     EISSN: None     Source Type: Journal    
DOI: 10.1016/0922-4106(92)90134-H     Document Type: Article

References (15)

1. Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness
2. G proteins in signal transduction
3. Molecular biology of serotonin receptors
4. Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
5. Signal-transducing G proteins and antidepressant drugs evidence for modulation of α subunit gene expression in rat brain
6. oα subunits
7. Lithium decreases Gs, Gi-1 and Gi-2 α-subunit mRNA levels in rat cortex
8. G proteins: implications for psychiatry
9. Fluoxetine, a highly selective serotonin reuptake inhibitor: a review of preclinical studies
10. Diversity of G proteins in signal transduction
11. q
12. G protein diversity: a distinct class of α subunits is present in vertebrates and invertebrates
13. Gα12 and Gα13 subunits define a fourth class of G protein α subunits
14. The role of G proteins in transmembrane signalling
15. q class of G proteins