Development of GPIIb/IIIa antagonists as antithrombotic drugs

Trends in Pharmacological Sciences

Volumn 13, Issue C, 1992, Pages 413-417

  Nichols, Andrew J ^a   Ruffolo Jr , Robert R ^b   Huffman, William F ^c   Poste, George ^d   Samanen, James ^e  

^a AJ Nichols is Associate Fellow in Cardiovascular Pharmacology USA ^*  (United States)

^b RR Ruffolo Jr is Vice President and Director of Pharmacological Sciences USA ^*

^c WF Huffman is Director of Peptidomimetic Research USA ^*  (United States)

^d G Poste is President and Chairman of Research and Development Technologies USA ^*  (United States)

^e GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; GLYCOPROTEIN IIB; GLYCOPROTEIN IIIA; MONOCLONAL ANTIBODY; SKF 106760; SKF 107260; STREPTOKINASE; TICLOPIDINE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONTROLLED STUDY; DOG; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; ISCHEMIA; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; REVIEW; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION; THROMBOSIS;

AMINO ACID SEQUENCE; FIBRINOLYTIC AGENTS; HUMAN; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS;

EID: 0026671678     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-6147(92)90126-Q     Document Type: Review

References (29)

1. Exposure of platelet fibrinogen receptors by ADP and epinephrine.
2. Plaque fissures in human coronary thrombosis
3. Final Report on the Aspirin Component of the Ongoing Physicians' Health Study