Activation of Protein Kinase C by Phorbol Esters and Arachidonic Acid Required for the Optimal Potentiation of Glutamate Exocytosis

Journal of Neurochemistry

Volumn 59, Issue 4, 1992, Pages 1574-1577

  Herrero, Immaculada ^a   Miras‐Portugal, María Teresa ^a   Sánchez‐Prieto, José ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Arachidonic acid; Calcium; Glutamate exocytosis; Membrane potential; Phorbol esters; Protein kinase C; Synaptosomes

Indexed keywords

4 AMINOPYRIDINE; 4BETA PHORBOL DIBUTYRATE; ARACHIDONIC ACID; CALCIUM ION; GLUTAMIC ACID; PROTEIN KINASE C; STAUROSPORINE;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CALCIUM CELL LEVEL; CELL MEMBRANE DEPOLARIZATION; CONCENTRATION; ENZYME ACTIVATION; EXOCYTOSIS; MALE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT;

4-AMINOPYRIDINE; ANIMAL; ARACHIDONIC ACID; CELL MEMBRANE; DRUG SYNERGISM; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; EXOCYTOSIS; GLUTAMATES; GLUTAMIC ACID; MALE; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T; TETRADECANOYLPHORBOL ACETATE;

EID: 0026671311     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1992.tb08478.x     Document Type: Article

References (28)

1. An ion channel locus for the protein kinase C potentiation of transmitter release from guinea pig cerebrocortical synaptosomes.
2. Direct activation of calcium activated, phospholipid dependent protein kinase by tumor‐promoting phorbol esters.
3. Phorbol ester translocation of protein kinase C in guinea‐pig synaptosomes and the potentiation of calcium‐dependent glutamate release
4. 2+ indicators with greatly improved fluorescence properties.
5. Glutamate exocytosis is inhibited by free fatty acids released from rat cerebrocortical synaptosomes.
6. Inhibition of glutamate release by arachidonic acid in rat cerebrocortical synaptosomes.
7. PKC‐independent inhibition of glutamate exocytosis by arachidonic acid in rat cerebrocortical synaptosomes.
8. Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo.
9. 2+ currents in mouse neuroblastoma cells.
10. 3H]‐glutamate.
11. 2+.
12. 2+.
13. 2+ and phospholipids.
14. Calcium‐transport and proton electrochemical potential in mitochondria from cerebral cortex and rat heart.
15. Calciumdependent and ‐independent release of glutamate from synaptosomes monitored by continuous fluorimetry.
16. Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes.
17. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
18. Synaptosomal protein kinase C subspecies: B. Down‐regulation promoted by phorbol ester and its effect on evoked norepinephrine release.
19. 2+‐independent release of glutamate during in vitro anoxia in isolated nerve terminals.
20. Protein kinase C subspecies in adult rat hippocampal synaptosomes. Activation by diacylglycerol and arachidonic acid.
21. Synaptosomal protein kinase C subspecies: A. Dynamic changes in the hippocampus and cerebellar cortex concomitant with synaptogenesis.
22. Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase'C activation: its possible implications
23. Phorbol esters potentiate rapid dopamine release from median eminence and striatal synaptosomes
24. Inhibition by cyclic AMP of phorbol ester‐potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
25. Studies on the mechanism by which cyanine dyes measure membrane potentials in red blood cells and phosphatidylcholine vesicles
26. 2+‐dependent regulation of presynaptic stimulus‐secretion coupling. J.
27. Fatty acid activation of protein kinase C: dependence on diacylglycerol.
28. 2+/calmodulin‐dependent protein kinase II.