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Tetrahedron Letters
Volumn 33, Issue 41, 1992, Pages 6107-6110
Kedarcidin chromophore: Structure elucidation of the amino sugar kedarosamine
Author keywords

amino sugar; chromoprotien; kedarcidin; kedarosamine
Indexed keywords

AMINOSUGAR; ANTINEOPLASTIC ANTIBIOTIC; KEDARCIDIN;
EID: 0026670459     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)60018-7     Document Type: Article
Times cited : (20)
References (7)
  • 2
    • 84919180194 scopus 로고    scopus 로고
    • 2; mobile phase: dichloromethane-acetone-ammonium hydroxide 10:2:0.2 v/v) of the basic fraction yielded 10 mg kedarosamine methyl glycosides (27% yield).; detection: vanillin-sulfuric acid spray reagent. The low yield may be due to the apparent volatility of the amino sugar amino glycoside and/or possible co-distillation with solvent upon evaporation.
  • 3
    • 84919180193 scopus 로고    scopus 로고
    • + m/z 372.0806; calcd 372.0810).
  • 4
    • 84919180192 scopus 로고    scopus 로고
    • 2 with a = 20.999(4), b = 5.9840(10), c = 14.824(3) Å and β = 112.83(1)°. A half sphere of data was collected using θ:2θ scans and CuKα radiation. A total of 2670 Friedel-redundant data were used in the analysis. The final R-factor was 0.053 and the absolute configuration was established by the η- method (1.00, 8) for the stereoisomer shown). This same absolute configuration was indicated by Hamilton's test since the R-factor for the L-stereoisomer shown in Fig. 3 is 0.053 while the enantiomer (D-isomer) has an R-factor of 0.060. Aromatic ring stacking appears to play an important role in the crystals since the essentially parallel rings are separated by 6.0 Å with an interplanar angle of only 8°. Additional crystallographic parameters are available from the Cambridge Crystallographic Data Centre, University [[Truncated]]
  • 7
    • 84919180191 scopus 로고    scopus 로고
    • D. R. Langley, T. W. Doyle, manuscripts in preparation.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.