Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene

The Lancet

Volumn 340, Issue 8826, 1992, Pages 987-991

  Tienari, P J ^a,b   Sajantila, A ^a   Peltonen, L ^a   Wikström, J ^b   Palo, J ^b  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN BASIC PROTEIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; FINLAND; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL;

ADULT; AGED; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 18; CONFOUNDING FACTORS (EPIDEMIOLOGY); DNA; FEMALE; FINLAND; GENE FREQUENCY; GENES, DOMINANT; GENETIC PREDISPOSITION TO DISEASE; HUMAN; LINKAGE (GENETICS); MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; PEDIGREE; POLYMORPHISM (GENETICS); SUPPORT, NON-U.S. GOV'T;

EID: 0026670087     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0140-6736(92)93007-A     Document Type: Article

References (29)

1. Epidemiology of multiple sclerosis
2. The epidemiology of multiple sclerosis in Finland: increase in prevalence and stability of foci in high-risk areas
3. Studies on the clustering of multiple sclerosis in Finland II microepidemiology in one high-risk county with special reference to familial cases
4. The age-specific prevalence ratio of familial multiple sclerosis
5. The mystery of the origin of multiple sclerosis
6. Genetic factors in the aetiology of multiple sclerosis
7. HLA typing in MS sib pairs
8. Multiple sclerosis: possible immunological mechanisms
9. DNA length polymorphism located 5' to the human myelin basic protein gene
10. n 5' to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length polymorphism
11. DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis
12. The Finnish population structure: a genetic and genealogical study
13. New diagnostic criteria for multiple sclerosis: guidelines for research protocols
14. MRI in the diagnosis of MS
15. Criteria for an increased specificity of MRI interpretations in elderly subjects with suspected multiple sclerosis
16. Amplification of a variable number of tandem repeats (VNTR) locus (pMCT118) by the polymerase chain reaction (PCR) and its application to forensic science
17. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
18. PCR amplification of alleles at the D1S80 locus: comparison of a Finnish and north American caucasian population sample, and forensic casework evaluation
19. The human myelin basic protein gene: chromosomal localization and RFLP analysis
20. Genetic susceptibility to multiple sclerosis
21. A long term prospective study of optic neuritis: evaluation of risk factors
22. Risk of developing multiple sclerosis after uncomplicated optic neuritis: a long term prospective study
23. Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice
24. mld) mutant mouse
25. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity