SCOPUS 정보 검색 플랫폼

Volumn 256, Issue 5060, 1992, Pages 1205-1210

Identification of heregulin, a specific activator of p185erbB2

(15) Holmes, William E a Sliwkowski, Mark X a Akita, Robert W a Henzel, William J a Lee, James a Park, John W a Yansura, Daniel a Abadi, Nasrin a Raab, Helga a Lewis, Gail D a Shepard, H Michael a,b Kuang, Wun Jing a Wood, William I a Goeddel, David V a Vandlen, Richard L a

a GENENTECH INC (United States)

b MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ENZYME ACTIVATOR; NEU DIFFERENTIATION FACTOR; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN;

ARTICLE; BINDING KINETICS; BINDING SITE; BREAST TUMOR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTO ONCOGENE; TUMOR CELL;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CODON; COMPARATIVE STUDY; CULTURE MEDIA; DNA-BINDING PROTEINS; EPIDERMAL GROWTH FACTOR; FEMALE; GLYCOPROTEINS; HUMAN; KINETICS; MOLECULAR SEQUENCE DATA; NEUREGULINS; OLIGONUCLEOTIDE PROBES; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN-TYROSINE KINASE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENES; RECEPTOR, ERBB-2; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION;

EID: 0026659262 PISSN: 00368075 EISSN: None Source Type: Journal
DOI: 10.1126/science.256.5060.1205 Document Type: Article

Times cited : (931)

References (50)

1
- 0023942517
- (1988) Annu. Rev. Biochem , vol.57 , pp. 443
- Yarden, Y.¹ Ullrich, A.²

2
- 0021273420
- (1984) Nature , vol.309 , pp. 418
- Ullrich, A.¹

3
- 0024326947
- (1989) Proc. Natl. Acad. Sci. U.S.A , vol.86 , pp. 9193
- Kraus, M.H.¹ Issing, W.² Miki, T.³ Popescu, N.C.⁴ Aaronson, S.A.⁵

4
- 0022399581
- (1985) Science , vol.230 , pp. 1132
- Coussens, L.¹

5
- 0022406444
- (1985) Science , vol.229 , pp. 974
- King, C.R.¹ Kraus, M.H.² Aaronson, S.A.³

6
- 37049183697
- (1987) Science , vol.235 , pp. 177
- Slamon, D.J.¹

7
- 0024337144
- (1989) Science , vol.244 , pp. 707
- Slamon, D.J.¹

8
- 0025974889
- (1991) Cancer Res , vol.51 , pp. 1034
- Yonemura, Y.¹

9
- 0025129959
- (1990) Gynecol. Oncol , vol.38 , pp. 364
- Borst, M.P.¹

10
- 0025708183
- (1990) Cancer Res , vol.50 , pp. 5184
- Kern, J.A.¹

11
- 0026316096
- (1991) Science , vol.254 , pp. 1146
- Aaronson, S.A.¹

12
- 0344127372
- (1988) Proc. Natl. Acad. Sci. U.S.A , vol.85 , pp. 1477
- Riedel, H.¹ Massoglia, S.² Schlessinger, J.³ Ullrich, A.⁴

13
- 0024593581
- (1989) Proc. Natl. Acad. Sci. U.S.A , vol.86 , pp. 3179
- Yarden, Y.¹ Weinberg, R.A.²

14
- 0025690737
- (1990) Biochemistry , vol.29 , pp. 11024
- Goldman, R.¹ Levy, R.B.² Peles, E.³ Yarden, Y.⁴

15
- 0024478054
- (1989) Mol. Cell. Biol , vol.9 , pp. 1165
- Hudziak, R.M.¹

16
- 85027754304
- (1991) Growth Regulation , vol.1 , pp. 72
- Samp, J.C.¹

17
- 0025968042
- (1991) Mol. Cell. Biol , vol.11 , pp. 979
- Kumar, R.¹ Shepard, H.M.² Mendelsohn, J.³

18
- 0026360077
- (1991) J. Biol. Chem , vol.266 , pp. 14300
- Scott, G.K.¹

19
- 0025094376
- (1990) Science , vol.249 , pp. 1552
- Lupu, R.¹

20
- 0025907986
- (1991) Biochemistry , vol.30 , pp. 3543
- Yarden, Y.¹ Peles, E.²

21
- 0026014466
- (1991) Proc. Natl. Acad. Sci. U.S.A , vol.88 , pp. 8582
- Dobashi, K.¹

22
- 0026041966
- (1991) Biochem. Biophys. Res. Commun , vol.179 , pp. 1536
- Davis, J.¹

23
- 0024469524
- HPLC-purified HRG-α was digested with lysine C in SDS (0.1%), 10 mM dithiothreitol, 0.1 M NH4HCO3 (pH 8.0) for 20 hours at 37°C and the resultant fragments were resolved on a Synchrom C4 column (4000 Å, 0.2 by 10 cm). The column was equilibrated in 0.1% TFA and eluted with a 1-propanol gradient in 0.1% TFA
- (1989) J. Biol. Chem , vol.264 , pp. 15905
- Henzel, W.J.¹ Stults, J.T.² Hsu, C.³ Aswad, D.W.⁴

24
- 0039820079
- An oligo(dT)-primed λgt10 D. Glover, Ed. (IRC Press, Oxford
- (1984) λgt10 and λgtl1 DNA Cloning Techniques: A Practical Approach
- Huynn, T.V.¹ Young, R.A.² Davis, R.W.³

25
- 0021016329
- cDNA library was constructed
- (1983) Gene , vol.25 , pp. 263
- Gubler, U.¹ Hoffman, B.J.²

26
- 0018639079
- with mRNA purified from MDA-MB-231 cells
- (1979) Biochemistry , vol.18 , pp. 5294
- Chirwin, J.M.¹ Przybyla, A.E.² MacDonald, R.J.³ Rutter, W.J.⁴

27
- 0022410222
- The following eightfold degenerate antisense deoxyoligonucleotide encoding the 13-amino acid sequence AEKEKTFCVNGGE (73) was designed on the basis of human codon frequency optima
- (1985) J. Mol. Biol , vol.183 , pp. 1
- Lathe, R.¹

28
- 0017681196
- Another cDNA designated clone 84 has an amino acid sequence identical to proHRG-β2 through amino acid 420. A stop codon at position 421 is followed by a different 3′-untranslated sequence
- (1977) Proc. Natl. Acad. Sci. U.S.A , vol.74 , pp. 5463
- Sanger, F.¹ Milken, S.² Coulson, A.R.³

29
- 0024386888
- (1989) Biochim. Biophys. Acta , vol.1008 , pp. 263
- Roberts, B.¹

30
- 0023047209
- (1986) Nucleic Acids Res , vol.14 , pp. 8427
- Bell, G.I.¹

31
- 0025904265
- (1991) Science , vol.251 , pp. 936
- Higashiyama, S.¹ Abraham, J.A.² Miller, J.³ Fiddes, J.C.⁴ Klagsbrun, M.⁵

32
- 0025266694
- (1990) Mol. Cell. Biol , vol.10 , pp. 1969
- Plowman, G.D.¹

33
- 0021752924
- (1984) Cell , vol.38 , pp. 287
- Derynck, R.¹ Roberts, A.B.² Winkler, M.E.³ Chen, E.Y.⁴ Goeddel, D.V.⁵

34
- 85027733281
- unpublished data
- Lee, J.¹ Wood, W.²

35
- 0025974889
- (1991) Cancer Res , vol.51 , pp. 1034
- Yonemura, Y.¹

36
- 0025912689
- (1991) Int. J. Cancer , vol.48 , pp. 668
- Jain, S.¹

37
- 0025901048
- (1991) Br. J. Cancer , vol.64 , pp. 79
- Lemoine, N.R.¹

38
- 0023829645
- (1988) Oncogene , vol.2 , pp. 283
- Yokota, J.¹

39
- 0025359146
- (1990) Oncogene , vol.5 , pp. 953
- Press, M.F.¹ Cordon-Cardo, C.² Slamon, D.J.³

40
- 0023270946
- and stimulated tyrosine phosphorylation of p185erbB2 with an EC50 of ~40 pM (26). Thus, the biological activity of HRG appears to reside in the EGF-like domain of the protein, and carbohydrate moieties are apparently not essential for activity in this assay. Purified rHRG-β1117–241 was used for binding and cross-linking experiments
- (1987) Gene , vol.55 , pp. 189
- Chang, C.N.¹ Rey, M.² Bochner, B.³ Hey-neker, H.⁴ Gray, G.⁵

41
- 85027754917
- unpublished data
- Lewis, G.¹ Shepard, H.M.²

42
- 85027732753
- unpublished data
- Sliwkowski, M.X.¹

43
- 0023304864
- (1987) Mol. Endo , vol.1 , pp. 216
- Davidson, N.E.¹ Gelman, E.P.² Lippman, M.E.³ Dickson, R.B.⁴

44
- 0023156382
- (1987) Biochemistry , vol.26 , pp. 1434
- Yarden, Y.¹ Schlessinger, J.²

45
- 0010281836
- C. H. Li, Ed. (Academic Press, New York
- (1973) Hormonal Proteins and Peptides , pp. 1-15
- Winzler, R.¹

46
- 0016342403
- (1974) Biochem. Soc. Symp , vol.40 , pp. 17
- Marshall, R.D.¹

47
- 0024517268
- (1989) Cell , vol.56 , pp. 1063
- Goldstein, L.A.¹

48
- 0015795516
- (1973) Biochem. J , vol.133 , pp. 529
- Bolton, A.E.¹ Hunter, W.M.²

49
- 0019061918
- (1980) Anal. Biochem , vol.107 , pp. 220
- Munson, P.¹ Robard, D.²

50
- 0023430930
- (1987) Proc. Natl. Acad. Sci. U.S.A , vol.84 , pp. 7159
- Hudziak, R.M.¹ Schlessinger, J.² Ullrich, A.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.