Cyclic adenosine 3’, 5’-monophosphate negatively regulates clusterin gene expression in leydig tumor cell lines

Endocrinology

Volumn 130, Issue 5, 1992, Pages 2745-2750

  Pignataro, Omar P ^a   Ming Feng, Zong ^a   Chen, Ching Ling C ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b POPULATION COUNCIL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CLUSTERIN; CYCLIC AMP;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; COMPLEMENT SYSTEM; CYTOLYSIS; GENE EXPRESSION; LEYDIG CELL; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SERTOLI CELL; STEROIDOGENESIS; TUMOR CELL LINE;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMAL; BLOTTING, NORTHERN; BUCLADESINE; CELL LINE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHORIONIC GONADOTROPIN; CYCLIC AMP; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; KINETICS; LEYDIG CELL TUMOR; MALE; MICE; POLY A; PROGESTERONE; RATS; RNA; RNA, MESSENGER; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUBULIN;

EID: 0026650899     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo.130.5.1374014     Document Type: Article

References (35)

1. Fritz IB, Burdzy K, Setchell B, Blaschuk O 1983 Ram rete testis fluid contains a protein (clusterin) which influences cell-cell interactions in vitro. Biol Reprod 28:1173-1188
2. Blaschuk O, Burdzy K, Fritz IB 1983 Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem 258:7714-7720
3. Cheng CY, Chen C-LC, Feng ZM, Marshall A, Bardin CW 1988 Rat clusterin isolated from primary Sertoli cell-enriched culture medium is sulfated glycoprotein-2 (SGP-2). Biochem Biophys Res Commun 155:398-404
4. Collard MW, Griswold MD 1987 Biosynthesis and molecular cloning of sulfated glycoprotein-2 secreted by rat Sertoli cells. Biochemistry 26:3297-3303
5. Montpetit ML, Lawless KR, Tenniswood MR 1986 Androgen repressed messages in the rat ventral prostate. Prostate 8:25-36
6. Buttyan R, Olsson CA, Pintar J, Chang C, Bandyk M, Sawczuk IS 1989 Induction of the TRPM-2 gene in cells undergoing programmed death. Mol Cell Biol 9:3473-3481
7. Bettuzzi S, Hiipakka RA, Gilna P, Liao S 1989 Identification of an androgen repressed mRNA in rat ventral prostate as coding for sulfated glycoprotein-2 by cDNA cloning and sequence analysis. Biochem J 257:293-296
8. Murphy BF, Kirszbaum L, Walker ID, d’Apice AJF 1988 SP-40, 40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis. J Clin Invest 81:1858-1864
9. Kirszbaum L, Sharpe JA, Murphy B, d’Apice AJF, Classon B, Hudson P, Walker ID 1989 Molecular cloning and characterization of the novel, human complement-associated protein, SP-40, 40: A link between the complement and reproductive systems. EMBO J 8:711-718
10. Jenne DE, Lowin B, Peitsch MC, Bootcher A, Schmitz G, Tschopp J 1991 Clusterin (complement lysis inhibitor) forms a high density lipoprotein complex with apolipoprotein A-I in human plasma. J Biol Chem 266:11030-11036
11. James RW, Hochstrasser A-C, Borghini I, Martin B, Pometta D, Hochstrasser D 1991 Characterization of a human high density lipoprotein-associated protein, NA1/NA2: Identity with SP-40, 40, an inhibitor of complement-mediated cytolysis. Arteriosclerosis and Thrombosis 11:645-652
12. Grima J, Zwain I, Lockshin RA, Bardin CW, Cheng CY 1990 Diverse secretory patterns of clusterin by epididymis and prostate/seminal vesicles undergoing cell regression after orchiectomy. Endocrinology 126:2989-2997
13. Morales C, Hugly S, Griswold MD 1987 Stage-dependent levels of specific mRNA transcripts in Sertoli cells. Biol Reprod 36:1035-1046
14. Hugly S, Roberts K, Griswold MD 1988 Transferrin and sulfated glycoprotein-2 messenger ribonucleic acid levels in the testis and isolated Sertoli cells of hypophysectomized rats. Endocrinology 122:1390-1396
15. Ascoli M 1981 Characterization of several clonal lines of cultured Leydig tumor cells: Gonadotropin receptors and steroidogenic responses. Endocrinology 108:88-95
16. Pignataro OP, Ascoli M 1990 Studies with insulin and insulin-like growth factor-I show that phosphatidylinositol-3, 4-biphosphate is not a mediator of the diverse actions of epidermal growth factor on MA-10 Leydig tumor cells. Mol Endocrinol 4:758-765
17. Pelham HRB 1982 A regulatory upstream promoter element in the drosophila Hsp70 heat shock gene. Cell 30:517-528
18. Auffray C, Fougeon F 1980 Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem 107:303-314
19. Aviv H, Leder P 1972 Purification of biologically active globulin messenger RNA by chromatography on oligothymidylic acid cellulose. Proc Natl Acad Sci USA 69:1408-1412
20. Lehrach H, Diamond D, Wozney JM, Boedtken H 1977 RNA molecular weight determinations by gel electrophoresis under de-naturing conditions, a critical reexamination. Biochemistry 16:4743-4751
21. Freeman DA 1987 Constitutive steroidogenesis in the R2C Leydig tumor cell line is maintained by adenosine 3’, 5’-cyclic monophosphate-independent production of a cycloheximide-sensitive factor that enhances mitochondrial pregnenolone biosynthesis. Endocrinology 120:124-132
22. Stocco DM, Chen W 1991 Presence of identical mitochondrial proteins in unstimulated constitutive steroid-producing R2C rat Leydig tumor and stimulated nonconstitutive steroid-producing MA-10 mouse Leydig tumor cells. Endocrinology 128:1918-1926
23. Collard MW, Day R, Akil H, Uhler MD, Douglass JO 1990 Sertoli cells are the primary site of prodynorphin gene expression in rat testis: Regulation of mRNA and secreted peptide levels by cyclic adenosine 3’, 5’-monophosphate analogs in cultured cells. Mol Endocrinol 4:1488-1496
24. Oyen O, Eskild W, Beebe SJ, Hansson V, Jahnsen T 1988 Biphasic response of 3’, 5’-cyclic adenosine monophosphate (cAMP) at the messenger ribonucleic acid level for a regulatory subunit of cAMP-dependent protein kinase. Mol Endocrinol 2:1070-1076
25. Heaton JH, Gelehrter TD 1990 Cyclic nucleotide regulation of plasminogen activator and plasminogen activator-inhibitor messenger RNAs in rat hepatoma cells. Mol Endocrinol 4:171-178
26. Slungaard A, Confer DL, Schubach WH 1987 Rapid transcriptional down-regulation of c-myc expression during cyclic adenosine monophosphate-promoted differentiation of leukemic cells. J Clin Invest 79:1542-1547
27. Martinez-Valdez H, Thompson E, Cohen A 1988 Coordinate transcriptional regulation of a and 5 chains of the T-cell antigen receptors by phorbol esters and cyclic adenosine 5’ -monophosphate in human thymocytes. J Biol Chem 263:9561-9564
28. Roesler WJ, Park EA, Klemm DJ, Liu J, Gurney AL, Vandenbark GR, Hanson RW 1990 Modulation of hormone response elements by promoter environment. Trends Endocrinol Metab 1:347-351
29. Habener JF 1990 Cyclic AMP response element binding proteins: A cornucopia of transcription factors. Mol Endocrinol 4:1087-1094
30. Deutsch P, Hoeffler J, Jameson J, Lin J, Habener J 1988 Structural determinants for transcriptional activation by cAMP-responsive DNA elements. J Biol Chem 263:18466-18472
31. Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR 1990 Transcription factor interactions: Selectors of positive or negative regulation from a single DNA element. Science 249:1266-1272
32. Ofir R, Swarki VJ, Rashid D, Verma IM 1991 CREB represses transcription of fos promoter: Role of phosphorylation. Gene Expression 1:55-60
33. Lamph WW, Dwarki VJ, Ofir R, Montminy M, Verma IM 1990 Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. Proc Natl Acad Sci USA 87:4320-4324
34. Bernath VA, Muro AF, Vitullo AD, Bley MA, Baranao JL, Korn-blihtt AR 1990 Cyclic AMP inhibits fibronectin gene expression in a newly developed granulosa cell line by a mechanism that suppresses cAMP-responsive element-dependent transcriptional activation. J Biol Chem 265:18219-18226
35. deSilva HV, Harmony JAK, Stuard WD, Gil CM, Robbins J 1990 Apolipoprotein J: Structure and tissue distribution. Biochemistry 29:5380-5389