Antipyretic Efficacy of Ibuprofen vs Acetaminophen

American Journal of Diseases of Children

Volumn 146, Issue 5, 1992, Pages 622-625

  Kauffman, Ralph E ^a   Sawyer, Laura A ^b   Scheinbaum, Monte L ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boots Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IBUPROFEN; PARACETAMOL; PLACEBO;

ANTIPYRETIC ACTIVITY; AREA UNDER THE CURVE; BODY TEMPERATURE; CHILD; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; FEMALE; FEVER; HUMAN; MALE; OTITIS MEDIA; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZATION; UPPER RESPIRATORY TRACT INFECTION;

ACETAMINOPHEN; BODY TEMPERATURE; CHILD; CHILD, PRESCHOOL; COMPARATIVE STUDY; DOUBLE-BLIND METHOD; FEMALE; FEVER; HUMAN; IBUPROFEN; MALE; SUPPORT, NON-U.S. GOV'T; TREATMENT OUTCOME;

EID: 0026648212     PISSN: 0002922X     EISSN: 15383628     Source Type: Journal    
DOI: 10.1001/archpedi.1992.02160170102024     Document Type: Article

References (15)

1. 1. Hurwitz ES, Barrett MJ, Bregman D, et al. Public Health Service study of Reye’s syndrome and medications. JAMA. 1987;257: 1905-1911.
2. 2. Amdekar YK, Desai RZ. Antipyretic activity of ibuprofen and paracetamol in children with pyrexia. Br J Clin Pract. 1985;39: 140-143.
3. 3. Heremans G, Dehaen F, Rom N, Ramet J, Verboven M, Loeb H. A single-blind parallel group study investigating the antipyretic properties of ibuprofen syrup versus acetylsalicylic acid syrup in febrile children. Br J Clin Pract. 1988;42: 245-247.
4. 4. Kandoth PW, Joshi MK, Joshi VR, Satoskar RS. Comparative evaluation of antipyretic activity of ibuprofen and aspirin in children with pyrexia of varied aetiology. J Int Med Res. 1984;12: 292-297.
5. 5. Sheth UK, Gupta K, Paul T, Pispati PK. Measurement of antipyretic activity of ibuprofen and paracetamol in children. J Clin Pharmacol. 1980;20: 672-675.
6. 6. Simila S, Kouvalainen K, Keinanen S. Oral antipyretic therapy: evaluation of ibuprofen. Scand J Rheumatol. 1976;5: 81-83.
7. 7. Wilson G, Guerra AJMS, Santo NT. Comparative study of the antipyretic effect of ibuprofen (oral suspension) and paracetamol (suppositories) in paediatrics. J Int Med Res. 1984;12: 250-254.
8. 8. Phadke MA, Paranjape PV, Joshi AS. Ibuprofen in children with infective disorders: antipyretic efficacy. Br J Clin Pract. 1985;39: 437-440.
9. 9. Kotob A. A comparative study of two dosage levels of ibuprofen syrup in children with pyrexia. J Int Med Res. 1985;13: 122-126.
10. 10. Walson PD, Galletta G, Braden NJ, Alexander L. Ibuprofen, acetaminophen, and placebo treatment of febrile children. Clin Pharmacol Ther. 1989;46: 9-17.
11. 11. Kauffman RE, Fox B, Gupta N. Ibuprofen antipyresis and pharmacokinetics in children. Pediatr Res. 1989;25: 67A.
12. 12. Temple AR. Pediatric dosing of acetaminophen. Pediatr Pharmacol. 1983;3: 321-327.
13. 13. Steans A, Manners PJ, Robinson IG. A multicenter, long-term evaluation of the safety and efficacy of ibuprofen syrup in children with juvenile chronic arthritis. Br J Clin Pract. 1990;44: 172-175.
14. 14. Van Biljon G. Reversible renal failure associated with ibuprofen in a child: a case report. S Afr Med J. 1989;76: 34-35.
15. 15. Dunn MJ, Simonson M, Davidson EW, Scharschmidt LA, Sedor JR. Nonsteroidal anti-inflammatory drugs and renal function. J Clin Pharmacol. 1988;28: 524-529.