Immunomodulatory effects of ursodeoxycholic acid on immune responses

Hepatology

Volumn 16, Issue 2, 1992, Pages 358-364

  Yoshikawa, Masahide ^a   Tsujii, Tadasu ^a   Matsumura, Keisuke ^a   Yamao, Junnichi ^a   Matsumura, Yoshinobu ^a   Kubo, Ryouichi ^a   Fukui, Hiroshi ^a   Ishizaka, Shigeaki ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOMODULATING AGENT; INTERLEUKIN 1; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; POLYINOSINIC POLYCYTIDYLIC ACID; URSODEOXYCHOLIC ACID;

ADULT; ARTICLE; BILIARY TRACT DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INTERFERON PRODUCTION; PLAQUE FORMING CELL; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; THYMOCYTE;

ADJUVANTS, IMMUNOLOGIC; ADULT; CYTOKINES; FEMALE; HUMAN; IMMUNOGLOBULINS; INTERLEUKIN-1; LIVER CIRRHOSIS, BILIARY; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGE; SUPPORT, NON-U.S. GOV'T; TAUROCHOLIC ACID; TUMOR CELLS, CULTURED; URSODEOXYCHOLIC ACID;

EID: 0026642157     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.1840160213     Document Type: Article

References (41)

1. Primary biliary cirrhosis
2. Primary biliary cirrhosis
3. Primary biliary cirrhosis
4. Immunohistochemical characterization of inflammatory infiltrates in primary biliary cirrhosis
5. Lymphocyte subsets in the liver of patients with primary biliary cirrhosis
6. Localisation of immunoglobulin on the liver cell surface in primary biliary cirrhosis
7. Analysis of hepatic T lymphocyte and immunoglobulin deposits in patients with primary biliary cirrhosis
8. Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis?
9. Ursodeoxycholic acid for primary biliary cirrhosis
10. Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double blind trial
11. Ursodeoxycholic acid for the treatment of primary biliary cirrhosis
12. Poupon R and the UDCA‐PBC study group. A multicenter, controlled trial of ursodior for the treatment of primary biliary cirrhosis
13. Effects of ursodeoxycholic acid and taurine on serum liver enzymes and bile acids in chronic hepatitis
14. Effect of ursodeoxycholic acid treatment on alanine amino transferase and γ‐glutamyl transpeptidase serum levels in patients with hypertansaminasemia
15. Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic acid treatment
16. Effect of ursodeoxycholic acid metabolism in primary biliary cirrhosis
17. + exchange inhibitors
18. Effects of bile acids on liver cell injury by cultured supernatants of activated liver adherent cells
19. Bile acid hepatotoxicity and the rationale of UDCA therapy in chronic cholestatic liver disease: some hypotheses
20. Hepatoprotective effect of ursodeoxycholate in experimental animals
21. Improvement of biliary enzyme levels and itching as a result of ursodeoxycholic acid in primary biliary cirrhosis
22. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: effect of ursodeoxycholic acid
23. Isolation of mononuclear cells and granulocytes from human blood
24. Chromosomes of 14 hematopoietic cell lines derived from peripheral blood of persons with and without chromosomal anomalies
25. Formal discussion: the role of transplantation in the experimental investigation of human leukemia and lymphoma
26. EBV‐transformation of surface IgA‐positive human lymphocytes
27. Ursodeoxycholic acid‐induced changes of plasma and urinary bile acids in primary biliary cirrhosis
28. A plaque assay for all cells secreting Ig of a given type of class
29. The functional relationship of the interleukins
30. Flow cytometry analysis using the Becton Dickinson FACScan
31. Expression of MHC products by normal and abnormal bile duct epithelium
32. Differential effect of interferon‐γ and interleukin‐2 on the induction of IgA and IgM anti‐dextran responses
33. The role of IL‐4 and IL‐5: characterization of a distinct helper T cell subset that makes IL‐4 and IL‐5: (TH2) and requires priming before induction of lymphokine secretion
34. Modulation of lymphocyte proliferation and immunoglobulin synthesis by interferon‐γ and type I interferons
35. Differential expression of MHC class II subregion products on bile duct epithelial cells and hepatocytes in patients with primary biliary cirrhosis
36. Recombinant interferon‐gamma increases HLA‐DR synthesis and expression
37. Surface regulation of histocompatibility antigens by interferon
38. A functional dichtomy in CD4 T lymphocytes
39. Regulation of T‐cell activation: differences among T‐cells subsets
40. Serum concentrations of ursodeoxycholic acid in portal venous and systemic venous blood of fasting humans as determined by isotope dilution‐mass spectrometry
41. Individual bile acids in portal venous and systemic blood serum of fasting man