Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation programs and does not cause neoplastic transformation

Journal of Cell Biology

Volumn 117, Issue 4, 1992, Pages 825-839

  Hauft, S M ^a   Kim, S H ^a   Schmidt, G H ^a   Pease, S ^a   Rees, S ^a   Harris, S ^a   Roth, K A ^a   Hansbrough, J R ^a   Cohn, S M ^a   Ahnen, D J ^a   Wright, N A ^a   Goodlad, R A ^a   Gordon, J I ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENTIATION ANTIGEN; VIRUS T ANTIGEN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL CYCLE S PHASE; CELL GROWTH; CELL LINE; CRYPT CELL; IMMUNOCYTOCHEMISTRY; INTESTINE CELL; INTESTINE EPITHELIUM; INTESTINE VILLUS; METAPHASE CHROMOSOME; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SIMIAN VIRUS 40; SMALL INTESTINE; TRANSGENIC MOUSE;

ANIMAL; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CARRIER PROTEINS; CELL CYCLE; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION; INTESTINAL MUCOSA; INTESTINE, SMALL; MICE; MICE, TRANSGENIC; NUCLEAR PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA; MAMMALIA; MUS MUSCULUS; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0026636048     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.117.4.825     Document Type: Article

References (0)