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Volumn 307, Issue 3, 1992, Pages 324-328
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Site-directed mutagenesis of a single residue changes the binding properties of the serotonin 5-HT2 receptor from a human to a rat pharmacology
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Author keywords
G protein coupled receptor; Mesulergine; Serotonin 5 HT2 receptor; Site directed mutagenesis
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Indexed keywords
5 CARBAMOYLTRYPTAMINE;
5 METHOXYTRYPTAMINE;
BUTACLAMOL;
COMPLEMENTARY DNA;
CYPROHEPTADINE;
KETANSERIN;
MESULERGINE;
METHYSERGIDE;
QUIPAZINE;
RITANSERIN;
SEROTONIN;
SEROTONIN RECEPTOR;
SPIPERONE;
ANIMAL TISSUE;
ARTICLE;
HUMAN;
LIGAND BINDING;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
RECEPTOR BINDING;
SITE DIRECTED MUTAGENESIS;
STRUCTURE ACTIVITY RELATION;
AMINO ACID SEQUENCE;
ANIMAL;
BASE SEQUENCE;
BINDING, COMPETITIVE;
CELL LINE;
CELL MEMBRANE;
CLONING, MOLECULAR;
COMPARATIVE STUDY;
DNA;
ERGOLINES;
HUMAN;
KETANSERIN;
MOLECULAR SEQUENCE DATA;
MUTAGENESIS, SITE-DIRECTED;
RATS;
RECEPTORS, SEROTONIN;
SEQUENCE HOMOLOGY, NUCLEIC ACID;
SPECIES SPECIFICITY;
TRANSFECTION;
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EID: 0026634655
PISSN: 00145793
EISSN: None
Source Type: Journal
DOI: 10.1016/0014-5793(92)80705-L Document Type: Article |
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Times cited : (85)
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References (22)
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