Does blood transfusion or hemorrhagic shock induce immunosuppression?

Journal of Trauma - Injury, Infection and Critical Care

Volumn 32, Issue 5, 1992, Pages 613-617

  Cue, Jorge I ^b   Peyton, James C ^a   Malangoni, Mark A ^c  

^a UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^b Medical College of Georgia   (Georgia)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; BLOOD TRANSFUSION; BLOOD VOLUME; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; HEMORRHAGIC SHOCK; IMMUNE DEFICIENCY; IMMUNE RESPONSE; INFECTION RISK; LEUKOCYTE COUNT; NONHUMAN; PERITONEUM CELL; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; SKIN ABSCESS; STAPHYLOCOCCUS AUREUS;

ABSCESS; ANIMAL; BLOOD TRANSFUSION; CELL MIGRATION INHIBITION; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOSUPPRESSION; ISOANTIGENS; RATS; RATS, INBRED ACI; RATS, INBRED LEW; RECEPTORS, IMMUNOLOGIC; SHOCK, HEMORRHAGIC; STAPHYLOCOCCAL INFECTIONS;

EID: 0026625494     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/00005373-199205000-00013     Document Type: Article

References (30)

1. Nichols RL, Smith JW, Klein DB, et al: Risk of infection after penetrating abdominal trauma. N Engl J Med 311:1065, 1984.
2. Dawes LG, Aprahamian C, Condon RE, et al: The risk of infection after colon injury. Surgery 100:796, 1986.
3. Tartter DI, Driefuss RM, Malon AM, et al: Relationship of post operative septic complications and blood transfusions in patients with Crohn’s disease. Am J Surg 155:43, 1988.
4. Wobbes T, Bemelmans BLH, Kuypers JHC, et al: Risk of postop erative septic complications after abdominal surgical treatment in relation to perioperative blood transfusion. Surg Gynecol Obstet 171:59, 1990.
5. Wilson RF, Dulchavsky SA, Soullier G, et al: Problems with 20 or more blood transfusions in 24 hours. Am Surg 53:410, 1987.
6. Abraham E, Regan RF: The effects of hemorrhage and trauma on interleukin 2 production. Arch Surg 120:1341, 1985.
7. Stephan RN, Kuppert S, Geha AS, et al: Hemorrhage without tissue trauma produces immunosuppression and enhances sus-ceptibility to sepsis. Arch Surg 122:62, 1987.
8. Waymack JP, Rapien J, Garnett D, et al: Effect of transfusion on immune function in a traumatized animal model. Arch Surg 121:50, 1986.
9. Esrig BC, Frazee L, Stephenson SF, et al: The predisposition to infection following hemorrhagic shock. Surg Gynecol Obstet 144:915, 1977.
10. Livingston DH, Shumate CD, Polk HC Jr, et al: More is better: Antibiotic management after hemorrhagic shock. Ann Surg 208:451, 1988.
11. Livingston DH, Malangoni MA: An experimental study of suscep tibility to infection after hemorrhagic shock. Surg Gynecol Obstet 168:138, 1989.
12. Malangoni MA, Livingston DH, Sonnenfeld G, et al: Interferon gamma and tumor necrosis factor alpha: Use in gram-negative infection after shock. Arch Surg 125:444, 1990.
13. Heyd TJ, Perez RV, Trocki O, et al: Manipulations of arachidonic acid metabolism using a 5-lipoxygenase inhibitor in transfusion- induced immunosuppression. Transplant Proc 20:1186, 1988.
14. Kaplan JE, Saba TM: Humoral deficiency and reticuloendothelial depression after traumatic shock. Am J Physiol 230:7, 1976.
15. Ogle CK, Woods S, Nagy H, et al: In vitro test on macrophage prostaglandin E2 and thromboxane B production after blood transfusion. Transplant Proc 20:1179, 1988.
16. Waymack JP, Balakrishnan K, Mc Neal N, et al: Effect of blood transfusions on macrophage-lymphocyte interaction in an animal model. Ann Surg 204:681, 1986.
17. Waymack JP, Galion L, Barcelli U, et al: Effect of blood transfu sions on immune function: III. Alterations in macrophage arachidonic acid metabolism. Arch Surg 122:55, 1987.
18. Galandiuk S, George CD, Pietsch JD, et al: An experimental assessment of the effect of blood transfusion on susceptibility to bacterial infection. Surgery 108:567, 1990.
19. Chaudry IH, Ayala A, Ertel W, et al: Hemorrhage and resuscitation: Immunologic aspects. Am J Physiol 259:663, 1990.
20. Fink MP, Gardiner M, Mac Vittie TJ: Sublethal hemorrhage im pairs the acute peritoneal inflammatory response in the rat. J Trauma 25:234, 1985.
21. Gascon P, Zoumbos NC, Young NS: Immunologic abnormalities in patients receiving multiple blood transfusions. Ann Intern Med 100:173, 1984.
22. Hau T, Lee JT, Simmons RL: Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis: IV. The adjuvant effect of hemoglobin in granulocytopenic rats. Surgery 89:189, 1981.
23. Marshall NE, Ziegler HK: Role of lipopolysaccharide in induction of la expression during infection with gram-negative bacteria. Infect Immun 57:1556, 1989.
24. Murray HW: Interferon-gamma, the activated macrophage, and host defense against microbial challenge. Ann Intern Med 108:595, 1988.
25. Ziegler HK, Staffileno LK, Wentworth P: Modulation of la expres sion by lipopolysaccharide. I. Induction of la expression in vivo. J Immunol 133:1825, 1984.
26. Altman PL, Katz DD (eds): Inbred and genetically defined strains of laboratory animals. FASEB J 3:321, 1979.
27. Miles AA, Miles EM, Burke J: The value and the duration of defence reactions of the skin to the primary lodgement of bacteria. J Exp Pathol 38:79, 1957.
28. Abraham E, Chang Y: Effects of hemorrhage on inflammatory response. Arch Surg 119:1154, 1984.
29. Kisala JM, Stephan RN, Harkema JM: Does blood transfusion increase mortality from sepsis? Circ Shock 24:290, 1988.
30. Hansbrough JF, Peterson V, Kortz E, et al: Postburn immuno suppression in an animal model: Monocyte dysfunction induced by burned tissue. Surgery 93:415, 1983