Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms

Veterinary Immunology and Immunopathology

Volumn 35, Issue 1-2, 1992, Pages 167-175

  Hartmann, K ^a   Donath, A ^a   Beer, B ^a   Egberink, H F ^b   Horzinek, M C ^b   Lutz, H ^c   Hoffmann Fezer, G ^d   Thum, I ^d   Thefeld, S ^d  

^a UNIVERSITY OF MUNICH   (Germany)

^b Department of Infectious Diseases and Immunology   (Netherlands)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d Institute for Immunology Gesellschaft für Strahlenforschung Munich Germany ^*

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; CD4 ANTIGEN; CD8 ANTIGEN; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; FELINE IMMUNODEFICIENCY VIRUS; FELINE LEUKEMIA VIRUS; NONHUMAN; SUBCUTANEOUS DRUG ADMINISTRATION; VIRUS INFECTION;

ADENINE; ANIMAL; ANTIVIRAL AGENTS; CATS; CD4-CD8 RATIO; CD4-POSITIVE T-LYMPHOCYTES; DOUBLE-BLIND METHOD; ENZYME-LINKED IMMUNOSORBENT ASSAY; FELINE ACQUIRED IMMUNODEFICIENCY SYNDROME; GENE PRODUCTS, GAG; HEMATOCRIT; IMMUNODEFICIENCY VIRUS, FELINE; INJECTIONS, SUBCUTANEOUS; LEUKEMIA VIRUS, FELINE; LEUKEMIA, FELINE; T-LYMPHOCYTES, SUPPRESSOR-EFFECTOR; ZIDOVUDINE;

EID: 0026619819     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-2427(92)90129-E     Document Type: Article

References (10)

1. Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered
2. Potent anti-simian immunodeficiency virus (SIV) activity and pharmacokinetics of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in rhesus monkeys
3. Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound
4. Clinical pharmacokinetics of Zidovudine
5. Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine
6. Synthesis of 9-(2-phosphonomethoxyethyl)adenine and related compounds
7. Early therapy of feline leukemia virus infection (FeLV-FAIDS) with 9-(2-phosphonyl-methoxyethyl)adenine (PMEA)
8. 3′-Azido-3′-desoxythymidine: an antiretroviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic lentivirus type III/lymphadenopathy associated virus in vitro
9. Feline immunodeficiency virus, a model for reverse transcriptase-targeted chemotherapy for acquired immune deficiency syndrome
10. 3′-Azido-3′-deoxythymidine in feline leukemia virus-infected cats: a model for therapy and prophylaxis of AIDS