Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand

Molecular Pharmacology

Volumn 41, Issue 3, 1992, Pages 549-560

  Costa, T ^a   Ogino, Y ^a   Munson, P J ^a   Onaran, H O ^a   Rodbard, D ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; LIGAND; RECEPTOR;

ARTICLE; BINDING SITE; CELL MEMBRANE; COMPETITIVE INHIBITION; DISSOCIATION CONSTANT; DRUG EFFICACY; ENZYME ACTIVITY; KINETICS; LIGAND BINDING; MODEL; PRIORITY JOURNAL; RECEPTOR AFFINITY; THERMODYNAMICS;

BINDING, COMPETITIVE; CELL LINE; CYCLIC AMP; ENDORPHINS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; LIGANDS; RADIOLIGAND ASSAY; RECEPTORS, CELL SURFACE; SODIUM; THERMODYNAMICS;

EID: 0026608113     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)