Cholesterol inhibition, cancer, and chemotherapy

The Lancet

Volumn 339, Issue 8802, 1992, Pages 1154-1156

  Buchwald, Henry ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; MITOMYCIN C;

ADJUVANT THERAPY; CANCER; CARCINOGENESIS; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; HUMAN; HYPOTHESIS; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SHORT SURVEY;

ADJUVANTS, PHARMACEUTIC; ANIMAL; ANTINEOPLASTIC AGENTS; CHOLESTEROL; DOGS; DRUG EVALUATION, PRECLINICAL; HUMAN; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYPERCHOLESTEROLEMIA; LOVASTATIN; MEVALONIC ACID; MICE; NEOPLASMS; NEOPLASMS, EXPERIMENTAL; RATS;

EID: 0026607503     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0140-6736(92)90744-N     Document Type: Article

References (27)

1. Plasma cholesterol, coronary heart disease, and cancer in the Renfrew and Paisley survey
2. Cancer mortality and lipid and lipoprotein levels: the lipid research clinics program mortality follow-up study
3. Total serum cholesterol and triglycerides and risk of breast cancer: a prospective study of 24,329 Norwegian women
4. Risk of cancer and death in relation to serum cholesterol: a longitudinal study in an eastern Finnish population with high overall cholesterol level
5. Plasma cholesterol and cancer morbidity and mortality in an adult community.
6. Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolemia. Report of the Program on the Surgical Control of the Hyperlipidemias (POSCH)
7. Cancer incidence and cancer mortality in relation to serum cholesterol
8. Plasma lipids and morality: a source of error
9. Cholesterol distribution between the two halves of the lipid bilayer of human erythrocyte ghost membranes
10. Subcellular localization of the enzymes of cholesterol biosynthesis and metabolism in rat liver
11. Regulation of the mevalonate pathway
12. Genetic and pharmacological suppression of oncogenic mutations in RAS genes of yeast and humans
13. p21ras is modified by a farnesyl isoprenoid
14. 14C] mevalonate
15. Deletion of the cholesterol-negative feedback system in liver tumors
16. The role of cholesterol in malignancy
17. Effect of cholesterol-free, fat-free diet and hypocholesterolemic agents on growth of transplantable animal tumours
18. Cancer, cholesterol and cholestyramine
19. Retarding Novikoff tumor growth by altering host rat cholesterol metabolism
20. Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
21. Effects of mevinolin and mevalonate on cell growth in several transformed cell lines
22. Modulation of metastatic ability by inhibition of cholesterol synthesis
23. Inhibition of hepatoma tissue culture-4 growth by lovastatin: a novel chemotherapeutic strategy
24. Current status of implantable drug delivery systems for patients requiring chronic drug administration
25. The physiological disposition of lovastatin
26. Preclinical evaluation of lovastatin