In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats

Hypertension

Volumn 19, Issue 6, 1992, Pages 692-696

  Yamamoto, Katsuhiro ^a   Chappell, Mark C ^a   Brosnihan, K Bridget ^a   Ferrario, Carlos M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Angiotensin converting enzyme; Angiotensin I; Angiotensin II; Enalaprilat; Enzyme inhibitors; Peptide peptidohydrolases; Spontaneously hypertensive rats

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN I; ANGIOTENSIN II [1-7]AMIDE[1 SARCOSINE]; DIPEPTIDYL CARBOXYPEPTIDASE; ENALAPRILAT; ENZYME INHIBITOR; MEMBRANE METALLOENDOPEPTIDASE; N (1 CARBOXY 3 PHENYLPROPYL)PHENYLALANYLISOSERINE; PROLYL ENDOPEPTIDASE; PROTEINASE; PROTEINASE INHIBITOR;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME INHIBITION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT;

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMAL; ENALAPRILAT; ENDOPEPTIDASES; HYPERTENSION; MALE; NEPRILYSIN; OSMOLAR CONCENTRATION; PEPTIDE FRAGMENTS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0026605307     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.19.6.692     Document Type: Article

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