Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix

Journal of Clinical Investigation

Volumn 89, Issue 2, 1992, Pages 373-380

  Saxena, Uday ^a,c   Klein, Michael G ^a   Vanni, Teresa M ^a   Goldberg, Ira J ^a,b  

^a College of Physicians and Surgeons ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c Pharmaceutical Research Division   (United States)

Author keywords

Atherosclerosis; Endothelial cells; Heparan sulfate; Proteoglycans; Very low density lipoproteins

Indexed keywords

HEPARAN SULFATE; LIPOPROTEIN LIPASE; PROTEOGLYCAN; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL TISSUE; AORTA; ARTICLE; ATHEROSCLEROSIS; ENDOTHELIUM; EXTRACELLULAR MATRIX; HUMAN; NONHUMAN; PRIORITY JOURNAL;

BIOLOGICAL TRANSPORT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; HUMAN; LIPOPROTEIN LIPASE; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026604386     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI115595     Document Type: Article

References (14)

1. Eckel, R. H. 1989. Lipoprotein lipase: a multifunctional enzyme relevant to common metabolic diseases. An. Engl. J. Med. 320:1060-1068.
2. Goldberg, I. J., N. A. Le, H. N. Ginsberg, R. M. Krauss, and F. T. Lindgren. 1988. Lipoprotein metabolism during acute inhibition of lipoprotein lipase in the cynomolgus monkey. J. Clin. Invest. 81:561-568.
3. Goldberg, I. J., W. S. Blaner, T. Vanni, M. Moukides, and R. Ramakrishnan. 1990. Role of lipoprotein lipase in the regulation of high density lipoprotein apolipoprotein metabolism. J. Clin. Invest. 86:463-473.
4. Kekki, M. 1980. Lipoprotein lipase action determining plasma high density lipoprotein cholesterol level in adult normolipaemics. Atherosclerosis. 37:143-150.
5. Zilversmit, D. B. 1979. Atherogenesis: a postprandial phenomenon. Circulation. 60:473-485.
6. O'Brien, K., D. Gordon, S. Deeb, M. Ferguson, and A. Chait. 1991. Localisation of lipoprotein lipase mRNA to foam cell-rich regions of human atherosclerotic plaques. Clin. Res. 39:335a. (Abstr.)
7. Yla-Herttuala, S., B. A. Lipton, M. E. Rosenfeld, I. Goldberg, D. Steinberg, and J. L. Witztum. 1991. Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions. Proc Natl. Acad. Sci. USA. 88:10143-10147.
8. Jonasson, L., G. Bondjers, and G. K. Hansson. 1987. Lipoprotein lipase in atherosclerosis: its presence in smooth muscle cell and absence from macrophages. J Lipid Res. 28:437-445.
9. Steinberg, D. 1983. Lipoproteins and atherosclerosis: a look back and a look ahead. Arteriosclerosis. 3:283-301.
10. Steinberg, D., S. Parthasarthy, T. E. Carew, J. C. Khoo, and J. L. Witztum. 1989. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320:915-924.
11. Bratzler, R. L., G. M. Chilsom, C. K. Colton, K. A. Smith, and R. S. Lees. 1977. The distribution of labeled low-density lipoproteins across the rabbit thoracic aorta in vivo. Artherosclerosis. 28:289-307.
12. Sloop, C. H., L. Dory, and P. S. Roheim. 1987. Interstitial fluid lipoproteins. J. Lipid Res 28:225-237.
13. Hoff, H. F., C. L. Heideman, R. L. Jackson, R. J. Bayardo, H.-S. Kim, and A. M. Gotto, Jr. 1975. Localisation patterns of plasma apolipoproteins in human atherosclerotic lesions. Circ Res. 37:72-79.
14. Schwenke, D. C., and T. E. Carew. 1989. Initiation of atherosclerotic lesion in cholesterol-fed rabbits. II. Selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries. Arteriosclerosis. 9:908-918.