Evaluation of p53 protein expression in Barrett's esophagus by two-parameter flow cytometry

Gastroenterology

Volumn 102, Issue 4 PART 1, 1992, Pages 1220-1228

  Ramel, Stig ^a,b,c   Reid, Brian J ^a,b,c   Sanchez, Carissa A ^a,b,c   Blount, Patricia L ^a,b,c   Levine, Douglas S ^a,b,c   Neshat, Katayoun ^a,b,c   Haggitt, Rodger C ^a,b,c   Dean, Patrick J ^a,b,c   Thor, Kjell ^a,b,c   Rabinovitch, Peter S ^a,b,c  

^a ERSTA HOSPITAL   (Sweden)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ANEUPLOIDY; ARTICLE; BARRETT ESOPHAGUS; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; DYSPLASIA; FLOW CYTOMETRY; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; MALIGNANT TRANSFORMATION; METAPLASIA; PRIORITY JOURNAL;

ADENOCARCINOMA; BARRETT ESOPHAGUS; DNA; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FLOW CYTOMETRY; GENES, P53; HUMAN; MUTATION; PROTEIN P53; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026597768     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/0016-5085(92)90759-r     Document Type: Article

References (58)

1. Barrett's esophagus
2. Barrett's esophagus: a review
3. Adenocarcinoma arising in Barrett's esophagus
4. Barrett's esophagus and adenocarcinoma
5. Barrett's esophagus. Comparison of benign and malignant cases
6. Adenocarcinoma in Barrett's esophagus
7. Rising incidence of adenocarcinoma of the esophagus and gastric cardia
8. Incidence of cancer of the esophagus in the US by histologic type
9. Value of endoscopic surveillance in the detection of neoplastic change in Barrett's oesophagus
10. Endoscopic surveillance for patients with Barrett's esophagus: Does the cancer risk justify the practice?
11. Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions
12. Observer variation in the diagnosis of dysplasia in Barrett's esophagus
13. Cancer in ulcerative colitis: Results of a 13 year prospective biopsy surveillance program
14. High grade dysplasia in Barrett's esophagus: a report of experience with 43 patients (abstr)
15. Barrett's esophagus. Correlation between flow cytometry and histology in detection of patients at risk for adenocarcinoma
16. Progression to cancer in Barrett's esophagus is associated with genomic instability
17. DNA content flow cytometry, and neoplastic progression in the gastrointestinal tract
18. Early Barrett's adenocarcinoma arises within a single aneuploid population (abstr)
19. Chromosomal rear-rangements in Barrett's esophagus. A premalignant lesion of esophageal adenocarcinoma
20. Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products
21. 17p Allelic Deletions and p53 Protein Overexpression in Barrett's Adenocarcinomas
22. T antigen is bound to a host protein in SV40-transformed cells
23. p53: oncogene or anti-oncogene?
24. Tumor suppressor genes
25. The p53 tumor suppressor gene
26. Chromosome 17 deletions and p53 mutations in colorectal carcinomas
27. Mutations in the p53 gene occur in diverse human tumor types
28. Chromosome 17p deletions and p53 gene mutations associated wilh the formation of malignant neurofibro-sarcomas in von Recklinghausen neurofibromatosis
29. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
30. Mutational hotspot in the p53 gene in human hepatocellular carcinomas
31. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis
32. Frequent mutation of the p53 gene in human esophageal cancer
33. Dominant oncogenes and tumor suppressor genes in the pathogenesis of lung cancer
34. p53: A frequent target for genetic abnormalities in lung cancer
35. Genetic and immuno-chemical analysis of mutant p53 in human breast cancer cell lines
36. p53 point mutation in HPV negative human cervical carcinoma cell lines
37. p53 Mutations in human cancers
38. Genetic basis for p53 overexpression in human breast cancer
39. The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)
40. Localization of gene for human p53 tumour antigen to band 17p13
41. Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro
42. Increased expression of mutant forms of p53 oncogene in primary lung cancer
43. Simultaneous monitoring of p53 protein and DNA content of colorectal adenocarcinomas by flow cytometry
44. Expression of the nuclear oncogene p53 in colon tumors
45. p53 expression in colorectal tumors
46. Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas
47. p53 mutations in colorectal cancer
48. Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the “hot spot” mutant phenotypes
49. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
50. Barrett's esophagus and esophageal adenocarcinoma
51. Adenocarcinoma and Barrett's esophagus. An overrated risk?
52. Endoscopic biopsy technique for acquiring larger mucosal samples
53. Modified histogram subtraction technique for analysis of flow cytometry data
54. Growth regulation of a cellular tumor antigen, p53, in nontransformed cells
55. Predictors of progression to malignancy in Barrett's esophagus: endoscopic, histologic and flow cytometric followup of a cohort (abstr)
56. Genetic alterations during colorectal-tumor development
57. Correlation of ultrastructural aberrations with dysplasia and flow cytometric abnormalities in Barrett's epithelium
58. Specialized metaplastic columnar epithelium in Barrett's esophagus. A comparative transmission electron microscopic study