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Volumn 98, Issue 4, 1992, Pages 475-480

Binding of beta-adrenergic receptors in human skin

Author keywords

association rate constant; Bmax; beta adrenergic receptor; cAMP; CMH; concentration of a competing agent that displaces 50 of the specifically bound radioligand from the receptor; crude membrane homogenates; cyclic 3 , 5 adenosine monophosphate; dissociation constant; dissociation rate constant; G protein; GTP; GTP (guanosine triphosphate) binding protein; guanosine triphosphate; IC50; ICYP; iodocyanopindolol; KD; koff; maximally bound receptor density; AR

Indexed keywords

BETA ADRENERGIC RECEPTOR; CYANOPINDOLOL I 125;

EID: 0026594043     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12499860     Document Type: Article
Times cited : (63)

References (49)
  • 1
    • 0020329170 scopus 로고
    • Adrenergic receptors in man. Direct identification, physiologic regulation, and clinical alterations
    • H.J. Motulsky P.A. Insel Adrenergic receptors in man. Direct identification, physiologic regulation, and clinical alterations N Engl J Med 29 1982 18 29
    • (1982) N Engl J Med , vol.29 , pp. 18-29
    • Motulsky, H.J.1    Insel, P.A.2
  • 2
    • 0021020377 scopus 로고
    • Characterization of beta-adrenergic receptors of cultured human epidermal keratinocytes
    • J. Gazith M.T. Cavey D. Cavey S. Braham U. Reichert Characterization of beta-adrenergic receptors of cultured human epidermal keratinocytes Biochem Pharmacol 32 1983 3397 3403
    • (1983) Biochem Pharmacol , vol.32 , pp. 3397-3403
    • Gazith, J.1    Cavey, M.T.2    Cavey, D.3    Braham, S.4    Reichert, U.5
  • 3
    • 0025744735 scopus 로고
    • High density of beta2-adrenoceptors in a human keratinocyte cell line with complete epidermal differentiation capacity (HaCaT)
    • 2-adrenoceptors in a human keratinocyte cell line with complete epidermal differentiation capacity (HaCaT) Arch Dermatol Res 283 1991 328 332
    • (1991) Arch Dermatol Res , vol.283 , pp. 328-332
    • Steinkraus, V.1    Körner, C.2    Steinfath, M.3    Mensing, H.4
  • 5
    • 0003083826 scopus 로고
    • cDNA for the human β2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor platelet-derived growth factor
    • 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor platelet-derived growth factor Proc Natl Acad Sci USA 84 1987 46 50
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 46-50
    • Kobilka, B.K.1    Dixon, R.A.F.2    Frielle, T.3
  • 7
    • 0021277201 scopus 로고
    • Mechanisms of membrane receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors
    • R.J. Lefkowitz M.G. Caron G.L. Stiles Mechanisms of membrane receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors N Engl J Med 310 1984 1570 1579
    • (1984) N Engl J Med , vol.310 , pp. 1570-1579
    • Lefkowitz, R.J.1    Caron, M.G.2    Stiles, G.L.3
  • 8
    • 0024994781 scopus 로고
    • β-adrenergic pathways in nonfailing and failing human ventricular myocardium
    • M.R. Bristow R.E. Hershberger J.D. Port β-adrenergic pathways in nonfailing and failing human ventricular myocardium Circulation 82 1990 112 125
    • (1990) Circulation , vol.82 , pp. 112-125
    • Bristow, M.R.1    Hershberger, R.E.2    Port, J.D.3
  • 10
    • 0023035106 scopus 로고
    • Assessment of the β-adrenergic pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response
    • M.B. Fowler J.A. Laser G.L. Hopkins W. Minobe M.R. Bristow Assessment of the β-adrenergic pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response Circulation 74 1986 1290 1302
    • (1986) Circulation , vol.74 , pp. 1290-1302
    • Fowler, M.B.1    Laser, J.A.2    Hopkins, G.L.3    Minobe, W.4    Bristow, M.R.5
  • 11
    • 0022525666 scopus 로고
    • Human β-adrenoceptors: relation of myocardial and lymphocyte β-adrenoceptor density
    • O-E Brodde R. Kretsch K. Ikezono H.R. Zerkowski J.C. Reidemeister Human β-adrenoceptors: relation of myocardial and lymphocyte β-adrenoceptor density Science 231 1986 1584 1585
    • (1986) Science , vol.231 , pp. 1584-1585
    • Brodde, O-E1    Kretsch, R.2    Ikezono, K.3    Zerkowski, H.R.4    Reidemeister, J.C.5
  • 12
    • 0019982539 scopus 로고
    • Decreased catecholamine sensitivity and β-adrenergic-receptor density in failing human hearts
    • M.R. Bristow R. Ginsburg W. Minobe Decreased catecholamine sensitivity and β-adrenergic-receptor density in failing human hearts N Engl J Med 307 1982 205 211
    • (1982) N Engl J Med , vol.307 , pp. 205-211
    • Bristow, M.R.1    Ginsburg, R.2    Minobe, W.3
  • 13
    • 0020574172 scopus 로고
    • Characterization of α- and β-adrenergic agonist stimulation of adenylate cyclase activity in human epidermal keratinocytes in vitro
    • E.K. Orenberg E.A. Pfendt D. Wilkinson Characterization of α- and β-adrenergic agonist stimulation of adenylate cyclase activity in human epidermal keratinocytes in vitro J Invest Dermatol 80 1983 503 507
    • (1983) J Invest Dermatol , vol.80 , pp. 503-507
    • Orenberg, E.K.1    Pfendt, E.A.2    Wilkinson, D.3
  • 14
    • 0022651624 scopus 로고
    • Receptor linked adenylate cyclase in the membranes of cultured human epidermal keratinocytes
    • M.T. Cavey D. Cavey B. Shroot U. Reichert J. Gazith Receptor linked adenylate cyclase in the membranes of cultured human epidermal keratinocytes Arch Dermatol Res 278 1986 293 297
    • (1986) Arch Dermatol Res , vol.278 , pp. 293-297
    • Cavey, M.T.1    Cavey, D.2    Shroot, B.3    Reichert, U.4    Gazith, J.5
  • 15
    • 85112907666 scopus 로고
    • Beta-adrenoceptors of intact human keratinocytes display functional coupling to the adenylate cyclase-cAMP system (abstr)
    • V. Steinkraus C. Körner V. Achterberg A. Reymann C. Woermann H. Mensing Beta-adrenoceptors of intact human keratinocytes display functional coupling to the adenylate cyclase-cAMP system (abstr) Arch Dermatol Res 283 1991 36
    • (1991) Arch Dermatol Res , vol.283 , pp. 36
    • Steinkraus, V.1    Körner, C.2    Achterberg, V.3    Reymann, A.4    Woermann, C.5    Mensing, H.6
  • 16
    • 0019732048 scopus 로고
    • (±)-[125Iodo]-cyanopindolol, a new ligand for β-adrenoceptors: identification and quantification of subclasses of beta-adrenoceptors in guinea pig
    • 125Iodo]-cyanopindolol, a new ligand for β-adrenoceptors: identification and quantification of subclasses of beta-adrenoceptors in guinea pig Naunyn Schmiedebergs Arch Pharmacol 317 1981 277 285
    • (1981) Naunyn Schmiedebergs Arch Pharmacol , vol.317 , pp. 277-285
    • Engel, G.1    Hoyer, D.2    Berthold, R.3    Wagner, H.4
  • 17
    • 84969001783 scopus 로고
    • The attractions of proteins for small molecules and ions
    • G. Scatchard The attractions of proteins for small molecules and ions Ann NY Acad Sci 51 1949 660 672
    • (1949) Ann NY Acad Sci , vol.51 , pp. 660-672
    • Scatchard, G.1
  • 18
    • 0004282959 scopus 로고
    • Neurotransmitter, hormone, or drug receptor binding methods
    • J.P. Bennett H.I. Yamamura Neurotransmitter, hormone, or drug receptor binding methods H.I. Yamamura S.J. Enna M.J. Kuhar Neurotransmitter Receptor Binding 1985 Raven Press New York 61 89
    • (1985) , pp. 61-89
    • Bennett, J.P.1    Yamamura, H.I.2
  • 19
    • 0020523811 scopus 로고
    • CGP-12177. A hydrophilic β-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells
    • M. Staehelin P. Simons K. Jaeggi N. Wigger CGP-12177. A hydrophilic β-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells J Biol Chem 258 1983 3496 3502
    • (1983) J Biol Chem , vol.258 , pp. 3496-3502
    • Staehelin, M.1    Simons, P.2    Jaeggi, K.3    Wigger, N.4
  • 21
    • 0022967556 scopus 로고
    • High β1-selectivity and favourable pharmacokinetics as the outstanding properties of bisoprolol
    • 1-selectivity and favourable pharmacokinetics as the outstanding properties of bisoprolol J Cardiovasc Pharmacol 8 1986 2 15
    • (1986) J Cardiovasc Pharmacol , vol.8 , pp. 2-15
    • Haeusler, G.1    Schliep, H.J.2    Schelling, P.3
  • 23
    • 0020324707 scopus 로고
    • Mechanism of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase
    • R.J. Lefkowitz M.G. Caron T. Michel J.M. Stadel Mechanism of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase Fed Proc 41 1982 2664 2670
    • (1982) Fed Proc , vol.41 , pp. 2664-2670
    • Lefkowitz, R.J.1    Caron, M.G.2    Michel, T.3    Stadel, J.M.4
  • 24
    • 0018862848 scopus 로고
    • Quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data
    • R.S. Kent A. De Lean R.J. Lefkowitz Quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data Mol Pharmacol 17 1980 14 23
    • (1980) Mol Pharmacol , vol.17 , pp. 14-23
    • Kent, R.S.1    De Lean, A.2    Lefkowitz, R.J.3
  • 25
    • 0016585634 scopus 로고
    • On the lack of response to catecholamine stimulation by the adenyl cyclase system in psoriatic lesions
    • K. Yoshikawa K. Adachi K.M. Halprin V. Levine On the lack of response to catecholamine stimulation by the adenyl cyclase system in psoriatic lesions Br J Dermatol 92 1975 619 624
    • (1975) Br J Dermatol , vol.92 , pp. 619-624
    • Yoshikawa, K.1    Adachi, K.2    Halprin, K.M.3    Levine, V.4
  • 27
    • 0015136356 scopus 로고
    • Psoriasis as a possible defect of the adenyl cyclase-cyclic AMP cascade
    • J.J. Voorhees E.A. Duell Psoriasis as a possible defect of the adenyl cyclase-cyclic AMP cascade Arch Dermatol 104 1971 352 358
    • (1971) Arch Dermatol , vol.104 , pp. 352-358
    • Voorhees, J.J.1    Duell, E.A.2
  • 28
    • 0018098507 scopus 로고
    • Cyclic AMP accumulation in psoriatic skin: differential responses to histamine, AMP, and epinephrine by the uninvolved and involved epidermis
    • H. Iizuka K. Adachi K.M. Halprin V. Levine Cyclic AMP accumulation in psoriatic skin: differential responses to histamine, AMP, and epinephrine by the uninvolved and involved epidermis J Invest Dermatol 70 1978 250 253
    • (1978) J Invest Dermatol , vol.70 , pp. 250-253
    • Iizuka, H.1    Adachi, K.2    Halprin, K.M.3    Levine, V.4
  • 29
    • 0018570067 scopus 로고
    • Studies on the plasma membrane of normal and psoriatic keratinocytes
    • J.M. Gommans M. Bergers P.E.J. Erp van Studies on the plasma membrane of normal and psoriatic keratinocytes Br J Dermatol 101 1979 413 419
    • (1979) Br J Dermatol , vol.101 , pp. 413-419
    • Gommans, J.M.1    Bergers, M.2    Erp van, P.E.J.3
  • 30
    • 0018861283 scopus 로고
    • Difference in response of psoriatic epidermis in cyclic AMP accumulation against certain adenyl cyclase agonists
    • K. Yoshikawa N. Mori K. Hadame S. Sakakibara Difference in response of psoriatic epidermis in cyclic AMP accumulation against certain adenyl cyclase agonists Acta Dermatovenereol 60 1980 95 98
    • (1980) Acta Dermatovenereol , vol.60 , pp. 95-98
    • Yoshikawa, K.1    Mori, N.2    Hadame, K.3    Sakakibara, S.4
  • 31
    • 0016292709 scopus 로고
    • Cutaneous and ocular reactions to practolol
    • R.H. Felix F.A. Ive M.G.C. Dahl Cutaneous and ocular reactions to practolol Br Med J 4 1974 321 324
    • (1974) Br Med J , vol.4 , pp. 321-324
    • Felix, R.H.1    Ive, F.A.2    Dahl, M.G.C.3
  • 33
    • 0023690506 scopus 로고
    • Increased cholera toxin-, and forskolin-induced cyclic AMP accumulations in psoriatic involved versus uninvolved or normal human epidermis
    • H. Iizuka S. Matsuo T. Tamura N. Ohkuma Increased cholera toxin-, and forskolin-induced cyclic AMP accumulations in psoriatic involved versus uninvolved or normal human epidermis J Invest Dermatol 91 1988 154 157
    • (1988) J Invest Dermatol , vol.91 , pp. 154-157
    • Iizuka, H.1    Matsuo, S.2    Tamura, T.3    Ohkuma, N.4
  • 34
    • 0019324183 scopus 로고
    • The synthesis of β-adrenergic receptors in cultured human lung cells: induction by glucocorticoids
    • C.M. Fraser J.C. Venter The synthesis of β-adrenergic receptors in cultured human lung cells: induction by glucocorticoids Biochem Biophys Res Commun 94 1980 390 397
    • (1980) Biochem Biophys Res Commun , vol.94 , pp. 390-397
    • Fraser, C.M.1    Venter, J.C.2
  • 35
    • 0021924165 scopus 로고
    • Glucocorticoid-induced alteration of beta-adrenergic adenylate cyclase response of epidermis
    • A. Ohkawara H. Iizuka Glucocorticoid-induced alteration of beta-adrenergic adenylate cyclase response of epidermis Arch Dermatol Res 277 1985 88 92
    • (1985) Arch Dermatol Res , vol.277 , pp. 88-92
    • Ohkawara, A.1    Iizuka, H.2
  • 36
    • 0014373373 scopus 로고
    • Epidermal dendritic cells: a quantitative study
    • A.S. Zelickson J.H. Mottaz Epidermal dendritic cells: a quantitative study Arch Dermatol 98 1968 652 659
    • (1968) Arch Dermatol , vol.98 , pp. 652-659
    • Zelickson, A.S.1    Mottaz, J.H.2
  • 37
    • 0002801038 scopus 로고
    • The structure and development of skin
    • K.A. Holbrook K. Wolff The structure and development of skin T.B. Fitzpatrick A.Z. Eisen K. Wolff I.M. Freedberg K.F. Austen Dermatology in General Medicine, 3rd ed 1987 McGraw Hill New York 93 131
    • (1987) , pp. 93-131
    • Holbrook, K.A.1    Wolff, K.2
  • 39
    • 0020381027 scopus 로고
    • Adrenergic receptors: biochemistry, regulation, molecular mechanism and clinical implications
    • J.A. Heinsimer R.J. Lefkowitz Adrenergic receptors: biochemistry, regulation, molecular mechanism and clinical implications J Lab Clin Med 100 1982 641 658
    • (1982) J Lab Clin Med , vol.100 , pp. 641-658
    • Heinsimer, J.A.1    Lefkowitz, R.J.2
  • 40
    • 0014194186 scopus 로고
    • Differentiation of receptor systems activated by sympathomimetic amines
    • A.M. Lands A. Arnold J.P. McAuliff F.P. Luduena T.G. Brown Differentiation of receptor systems activated by sympathomimetic amines Nature 214 1967 597 598
    • (1967) Nature , vol.214 , pp. 597-598
    • Lands, A.M.1    Arnold, A.2    McAuliff, J.P.3    Luduena, F.P.4    Brown, T.G.5
  • 41
    • 0021347385 scopus 로고
    • In vitro interactions of agonists and antagonists with β-adrenergic receptors
    • S.N. Abramson P.B. Molinoff In vitro interactions of agonists and antagonists with β-adrenergic receptors Biochem Pharmacol 33 1984 869 875
    • (1984) Biochem Pharmacol , vol.33 , pp. 869-875
    • Abramson, S.N.1    Molinoff, P.B.2
  • 42
    • 0021272384 scopus 로고
    • G proteins and dual control of adenylate cyclase
    • A.G. Gilman G proteins and dual control of adenylate cyclase Cell 36 1984 577 578
    • (1984) Cell , vol.36 , pp. 577-578
    • Gilman, A.G.1
  • 44
    • 0020069682 scopus 로고
    • Calcium ions and the control of proliferation in normal and cancer cells
    • A.C. Durham J.M. Walton Calcium ions and the control of proliferation in normal and cancer cells Biosci Rep 2 1982 15 30
    • (1982) Biosci Rep , vol.2 , pp. 15-30
    • Durham, A.C.1    Walton, J.M.2
  • 45
    • 0023881378 scopus 로고
    • Calcium and epithelial cell proliferation
    • A.L. Boynton Calcium and epithelial cell proliferation Miner Electrolyte Metab 14 1988 86 94
    • (1988) Miner Electrolyte Metab , vol.14 , pp. 86-94
    • Boynton, A.L.1
  • 46
    • 0020513440 scopus 로고
    • Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture
    • S.T. Boyce R.G. Ham Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture J Invest Dermatol 81 1983 335 405
    • (1983) J Invest Dermatol , vol.81 , pp. 335-405
    • Boyce, S.T.1    Ham, R.G.2
  • 47
    • 0020695954 scopus 로고
    • Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture. An ultrastructural study
    • H. Hennings K.A. Holbrook Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture. An ultrastructural study Exp Cell Res 143 1983 127 142
    • (1983) Exp Cell Res , vol.143 , pp. 127-142
    • Hennings, H.1    Holbrook, K.A.2
  • 48
    • 0021717130 scopus 로고
    • Calcium-induced reorganization of desmosomal components in cultured keratinocytes
    • F.M. Watt D.L. Mattey D.R. Garrod Calcium-induced reorganization of desmosomal components in cultured keratinocytes J Cell Biol 99 1984 2211 2215
    • (1984) J Cell Biol , vol.99 , pp. 2211-2215
    • Watt, F.M.1    Mattey, D.L.2    Garrod, D.R.3
  • 49
    • 0023552314 scopus 로고
    • Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes
    • A.I. Magee N.A. Lytton F.M. Watt Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes Exp Cell Res 172 1987 43 53
    • (1987) Exp Cell Res , vol.172 , pp. 43-53
    • Magee, A.I.1    Lytton, N.A.2    Watt, F.M.3


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