Chloroquine inhibits intracellular degradation but not secretion of Alzheimer β/A4 amyloid precursor protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 89, Issue 6, 1992, Pages 2252-2256

  Caporaso, Gregg L ^a   Gandy, Samuel E ^a,b,c   Buxbaum, Joseph D ^a   Greengard, Paul ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Brefeldin A; Dementia; Monensin; Proteolysis

Indexed keywords

AMYLOID PROTEIN; BREFELDIN A; CHLOROQUINE; MONENSIN; PROTEIN PRECURSOR;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PH; CONTROLLED STUDY; GOLGI COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SECRETION; STEM CELL;

AMMONIUM CHLORIDE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMAL; ANTIBIOTICS; AUTORADIOGRAPHY; BREFELDIN A; CHLOROQUINE; CYCLOPENTANES; GLYCOSYLATION; KINETICS; METHIONINE; MOLECULAR WEIGHT; MONENSIN; ORGANELLES; PC12 CELLS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SULFUR RADIOISOTOPES; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

ANIMALIA;

EID: 0026589836     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.89.6.2252     Document Type: Article

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