Human pharmacokinetics of N‐l‐leucyl‐doxorubicin, a new anthracycline derivative, and its correlation with clinical toxicities

Clinical Pharmacology & Therapeutics

Volumn 51, Issue 3, 1992, Pages 249-259

  Canal, Pierre ^a,b,c,d,e   Robert, Jacques ^a,b,c,d,e   Ramon, Marianne ^a,b,c,d,e   Baurain, Roger ^a,b,c,d,e   Tresca, Patricia ^a,b,c,d,e   de Forni, Marcel ^a,b,c,d,e   Marty, Michel ^a,b,c,d,e   Pujade‐Lauraine, Eric ^a,b,c,d,e   Bugat, Roland ^a,b,c,d,e   Magis, Alex ^a,b,c,d,e   Belpomme, Dominique ^a,b,c,d,e  

^a INSTITUT CLAUDIUS REGAUD   (France)

^b INSTITUT BERGONIÉ   (France)

^c Medgenix Group ^*  (Belgium)

^d Association Pour la Recherche Thérapeutique Anti Cancéreuse ^*  (France)

^e SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; DOXORUBICIN; DOXORUBICINOL; DRUG METABOLITE; LEURUBICIN; N LEUCYLDOXORUBICINOL; UNCLASSIFIED DRUG;

ADVANCED CANCER; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; PHARMACOKINETICS; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; STOMATITIS; THROMBOCYTOPENIA;

DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG EVALUATION; HUMAN; LEUKOCYTE COUNT; PLATELET COUNT; REGRESSION ANALYSIS; STOMATITIS;

EID: 0026589540     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.1992.19     Document Type: Article

References (0)