RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Cell

Volumn 68, Issue 5, 1992, Pages 855-867

  Shinkai, Yoichi ^a   Rathbun, 0Gary ^a   Lam, Kong Peng ^a   Oltz, Eugene M ^a   Stewart, Valerie ^a   Mendelsohn, Monica ^a   Charron, Jean ^a   Datta, Milton ^a   Young, Faith ^a   Stall, Alan M ^a   Alt, Frederick W ^a  

^a The Howard Hughes Medical Institute Department of Biochemistry College of Physicians Surgeons Columbia University New York ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LYMPHOCYTE SURFACE MARKER; RECOMBINASE; T LYMPHOCYTE RECEPTOR;

ADOLESCENT; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVITY; GENE LOCUS; GENE REARRANGEMENT; GENETIC RECOMBINATION; HOMOZYGOSITY; IMMUNOGLOBULIN STRUCTURE; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE DEPLETION; LYMPHOCYTE DIFFERENTIATION; MOUSE; MURINE LEUKEMIA VIRUS; NEWBORN; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; BASE SEQUENCE; DNA NUCLEOTIDYLTRANSFERASES; GENE REARRANGEMENT, T-LYMPHOCYTE; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES;

ABELSON MURINE LEUKEMIA VIRUS; ANIMALIA; MURINAE; MURINE LEUKEMIA VIRUS;

EID: 0026581936     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(92)90029-C     Document Type: Article

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