Role of muscarinic receptor subtypes in central antinociception

British Journal of Pharmacology

Volumn 105, Issue 1, 1992, Pages 77-82

  Bartolini, A ^a   Ghelardini, C ^a   Fantetti, L ^a   Malcangio, M ^a   Malmberg Aiello P ^a   Giotti, A ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

acetylcholine; Analgesia; antinociception; muscarinic agonists; muscarinic antagonists; muscarinic receptors; pain

Indexed keywords

[4 [(3 CHLOROPHENYL)CARBAMOYLOXY] 2 BUTYNYL]TRIMETHYLAMMONIUM; ARECAIDINE PROPARGYL ESTER; ATROPINE; CEVIMELINE; DICYCLOVERINE; HEMICHOLINIUM 3; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; NALOXONE; OTENZEPAD; PIRENZEPINE; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; HOT PLATE TEST; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; WRITHING TEST;

ANALGESIA; ANIMAL; MALE; MCN-A-343; MICE; PAIN MEASUREMENT; PIRENZEPINE; QUINUCLIDINES; RECEPTORS, MUSCARINIC; SUPPORT, NON-U.S. GOV'T;

EID: 0026570445     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1992.tb14213.x     Document Type: Article

References (40)

1. 2 muscarinic receptors in guinea‐pig ileum, atria and bronchi
2. New data concerning the interaction between cholinergic, enkephalinergic and serotoninergic system during analgesia
3. Antinociception induced by systemic administration of local anaesthetics depends on a central cholinergic mechanism
4. I.c.v. injected AFDX‐116 induces analgesia only when administered at very low doses
5. Non‐specificity of the mouse writhing test
6. 1 agonist with potential application in Alzheimer's disease
7. 1 agonist attenuates cognitive disfunction in AF64A‐treated rats
8. The central action of a metabolite of tremorine
9. Investigation into atropine‐induced antinociception
10. Methoctramine increases cholinergic neurotransmission by acting presynaptically
11. 2 receptor antagonist
12. 2 antagonist, discriminates among peripheral muscarine receptors
13. Characterization of muscarinic receptor subtypes human tissues
14. 2 antagonist methoctramine administered i.c.v
15. Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse
16. Pirenzepine distinguishes between different subclasses of muscarinic receptors
17. Muscarinic receptor subtypes: M‐1 and M‐2 Biochemical and functional characterization
18. Narcotic antagonists analgesics: interaction with cholinergic system
19. Antagonism of the frequency of phenylquinone‐induced writhing in the mouse by weak analgesics and nonanalgesics
20. Wirkungen des Arecolins auf das Zentralnervensystem
21. A comparison of the antinociceptive action of cholinomimetic and morphine‐like drugs
22. Antinociception after nicotine administration into the mesopontine tegmentum of rats: evidence for muscarinic actions
23. Selective inhibition of muscarinic receptors in intestinal smooth muscle
24. Muscarinic ganglionic stimulants: conformational analogues related to 4‐N‐(chlorophenyl) carbamoyloxil‐2‐butinyltri‐methylammonium chloride
25. Narkosepotenzierende und Analgetische Wirkung von 1,4‐dipyrrolidino‐2‐butin
26. Some actions of anticholinergic drugs
27. The opposing effects of atropine on nociception when given at low versus high doses
28. 2 muscarinic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation
29. 2 muscarinic receptors in the rat brain
30. Über struktur‐workungs‐bezeihungen von ungesattigten ester des arecaidins und dihydroarecaidins
31. Selective muscarinic agonists and antagonists in functional test
32. 1‐selective agonist: preferential effect on reversal of amnesia
33. Dicyclomine, benzexolo and oxybutynine distinguish between subclasses of muscarinic binding sites
34. 1 agonist, AF‐102B.
35. Determination and characterization of the antinociceptive activity of intracerebroventricularly administered acetylcholine
36. 3] acetylcholine release from rat hippocampal slices
37. 2 receptors: ligands, autoradiography and functions
38. Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain
39. 2 muscarinic acetylcholine receptor distribution in the rat brain: relation to cholinergic nuclei projections