Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

Cell

Volumn 68, Issue 2, 1992, Pages 377-395

  Leid, Mark ^a,b   Kastner, Philippe ^a,b   Lyons, Ruth ^a,b   Nakshatri, Harikrishna ^a,b   Saunders, Michael ^a,b   Zacharewski, Tim ^a,b   Chen, Jia Yang ^a,b   Staub, Adrien ^a,b   Garnier, Jean Marie ^a,b   Mader, Sylvie ^a,b   Chambon, Pierre ^a,b  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN; RECEPTOR; RETINOIC ACID; RETINOID BINDING PROTEIN; THYROID HORMONE; THYROID HORMONE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; HELA CELL; HUMAN; HUMAN CELL; INSECT; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN PURIFICATION; PROTEIN TARGETING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CLONING, MOLECULAR; DNA; HELA CELLS; HUMAN; MACROMOLECULAR SYSTEMS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PRECIPITIN TESTS; RECEPTORS, CELL SURFACE; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; REGULATORY SEQUENCES, NUCLEIC ACID; REPETITIVE SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TRETINOIN;

ANIMALIA; INSECTA; MURINAE;

EID: 0026570217     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(92)90478-U     Document Type: Article

References (98)

1. Encounters with Fos and Jun on the road to AP-1
2. Redox regulation of Fos and Jun DNA-binding
3. Cloning and expression of full-length cDNA encoding human vitamin D receptor
4. 3,5,3′-Triiodothyronine receptor auxiliary protein (TRAP) enhances receptor binding by interactions within the thyroid hormone response element
5. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins
6. Identification of a second human retinoic acid receptor
7. Retinoids, homeobox genes, and limb morphogenesis
8. Reading the retinoid signals
9. A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements
10. The family of retinoic acid nuclear receptors
11. Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist
12. 3 receptor
13. v-erbA oncogene abrogates growth inhibition of chicken embryo fibroblasts induced by retinoic acid
14. Identification of a retinoic acid responsive element in the retinoic acid receptor β gene
15. The PML-RARα fusion mRNA generated by the t(15; 17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
16. v-erbA overexpression is required to extinguish c-erbA function in erythroid cell differentiation and regulation of the erbA target gene CAII
17. Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
18. Interactions among a subfamily of nuclear hormone receptors: the regulatory zipper model
19. pEXPRESS: a family of expression vectors containing a single transcription unit active in prokaryotes, eukaryotes and in vitro
20. A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone
21. Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer
22. Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor
23. Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity
24. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
25. A versatile in vivo and in vitro eukaryotic expression vector for protein engineering
26. Receptors bound to antiprogestin form abortive complexes with hormone responsive elements
27. Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity
28. H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element
29. Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression
30. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
31. Chromosomal translocation t(15; 17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
32. Murine isoforms of retinoic acid receptor γ with specific patterns of expression
33. Structure, localization and transcriptional properties of two classes of retinoic acid receptor α (RAR-α) fusion proteins in acute promyelocytic leukemia (APL)
34. Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity
35. DNA bending by Fos and Jun: the flexible hinge model
36. The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily
37. The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors
38. A third human retinoic acid receptor, hRAR-γ
39. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer
40. Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization
41. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo
42. Thyroid hormone receptors form distinct nuclear protein-dependent and independent complexes with a thyroid hormone response element
43. Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor
44. Mouse retinoic acid receptor α2 isoform is transcribed from a promoter that contains a retinoic acid response element
45. Multiple isoforms of the mouse retinoic acid receptor α are generated by alternative splicing and differential induction by retinoic acid
46. 3
47. Analysis of monomeric-dimeric states of the estrogen receptor with monoclonal ant estrophilins
48. Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
49. Nuclear receptor that identifies a novel retinoic acid response pathway
50. A direct repeat in the cellular retinolbinding protein type II gene confers differential regulation by RXR and RAR
51. Developmental analysis of the retinoic acid-inducible RAR-β2 promoter in transgenic animals
52. Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene
53. 3 binding capacities are transcribed from opposite DNA strands of the same genetic locus
54. The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates
55. Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter
56. A single-stranded DNA-binding protein promotes the binding of the purified oestrogen receptor to its responsive element
57. Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response element
58. The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors
59. A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity
60. Identification and characterization of nuclear retinoic acid-binding activity in human myeloblastic leukemia HL-60 cells
61. Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site
62. Thyroid hormone receptor mutations that interfere with transcriptional activation also interfere with receptor interaction with a nuclear protein
63. Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor
64. Structure and origin of the acute promyelocytic leukemia myl/RARα cDNA and characterization of its retinoid-binding and transactivation properties
65. Thyroid hormone nuclear receptor
66. Activators and targets
67. Retinoic acid receptor γ: specific immunodetection and phosphorylation
68. A retinoic acid-responsive element in the apolipoprotein Al gene distinguishes between two different retinoic acid response pathways
69. A member of the RXR nuclear receptor family is expressed in neural-crest-derived cells of the developing chick peripheral nervous system
70. Retinoic acid receptors in the embryo
71. Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos
72. The c-erb-A protein is a high-affinity receptor for thyroid hormone
73. Repression of transcription mediated at a thyroid hormone response element by the v-erb-A
74. Beyond zinc fingers: steroid hormone receptors have a novel structural motif for DNA recognition
75. Something old, some things new: the steroid receptor superfamily in Drosophila
76. The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily
77. Thyroid hormone receptor and v-erbA
78. v-erbA oncogene function in neoplasia correlates with its ability to repress retinoic acid receptor action
79. Differential DNA binding by calf uterine estrogen and progesterone receptors results from differences in oligomeric states
80. A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter
81. Ligand-binding and heterodimerization activities of a conserved region in the ligand-binding domain of the thyroid hormone receptor
82. Use of T7 RNA polymerase to direct expression of cloned genes
83. Characterization of an autoregulated response element in the mouse retinoic acid receptor type β gene
84. Retinoic acid, a developmental signalling molecule
85. An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers
86. Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins
87. Distinct classes of transcriptional activating domains function by different mechanisms
88. 3 receptors
89. A retinoic acid-responsive element is present in the 5′ flanking region of the laminin B1 gene
90. The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element
91. The MyoD gene family: nodal point during specification of the muscle cell lineage
92. Structural organization and expression of the mouse estrogen receptor
93. Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1
94. Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor
95. Xenopus laevis α and β thyroid hormone receptors
96. Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin
97. Differentially expressed isoforms of the mouse retinoic acid receptor β are generated by usage of two promoters and alternative splicing