Optimal selection of metabolic fluxes for in vivo measurement. II. Application to Escherichia coli and hybridoma cell metabolism

Journal of Theoretical Biology

Volumn 155, Issue 2, 1992, Pages 215-242

  Savinell, Joanne M ^a   Palsson, Bernhard O ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ACETIC ACID; ACONITATE HYDRATASE; CITRATE SYNTHASE; FUMARATE HYDRATASE; ISOCITRATE DEHYDROGENASE; LYASE; MALATE DEHYDROGENASE; MALATE DEHYDROGENASE (DECARBOXYLATING); OXALOACETIC ACID; OXOGLUTARATE DEHYDROGENASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVATE DEHYDROGENASE; PYRUVATE KINASE; SUCCINATE DEHYDROGENASE; SYNTHETASE;

ALGORITHM; ANALYTICAL ERROR; ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; CELL LINE; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GLUCONEOGENESIS; HYBRIDOMA; IN VIVO STUDY; MATHEMATICS; MEASUREMENT; METABOLISM; METABOLITE; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY;

ANIMAL; ESCHERICHIA COLI; HYBRIDOMAS; METABOLISM; MODELS, BIOLOGICAL; SENSITIVITY AND SPECIFICITY; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0026566666     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/S0022-5193(05)80596-X     Document Type: Article

References (6)

1. Effects of dissolved oxygen on hybridoma cell growth, metabolism, and antibody production kinetics in continuous culture
2. Analysis of stoichiometry in metabolic networks
3. Optimal selection of metabolic fluxes for in vivo measurement. I. Development of mathematical methods
4. Network analysis of intermediary metabolism using linear optimization. II. Interpretation of Hybridoma cell metabolism
5. Branch point control by the phosphorylation state of isocitrate dehydrogenase