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19
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84912905080
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US. Pat. 2,768,962 (Oct. 30, 1956)
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(1957)
Chem. Abstr.
, vol.51
, pp. 6684b
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Krimm1
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20
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84912924682
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Ger. Pat. 948,157 (Aug. 30, 1956)
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(1958)
Chem. Abstr.
, vol.52
, pp. 18266e
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Krimm1
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31
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84912902418
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D. Desmaele, unpublished work.
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32
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84912941800
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F. Dumas, unpublished work.
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34
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84912950508
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A. Guingant, unpublished results.
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38
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84912928649
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H. Sdassi, J. d'Angelo, unpublished work.
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40
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84912902444
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M-A. Le Dréau, F. Dumas, J. d'Angelo, unpublished work.
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42
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84912930959
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N. Champion, D. Desmaele, J. d'Angelo, unpublished results.
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44
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84912948759
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G. Pain, D. Desmaele, J. d'Angelo, unpublished work.
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45
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84912945396
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M. Velayoudon, D. Desmaele, J. d'Angelo, unpublished results.
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46
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84912932608
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H. Hammami, A. Guingant, unpublished work.
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48
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84912950647
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T. Volpe, J. d'Angelo, unpublished results.
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50
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84912898748
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L. Ambroise, J. d'Angelo, unpublished results.
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53
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84912928620
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J. d'Angelo, unpublished results.
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55
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84912909488
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S. Pinheiro, D. Desmaele, A. Guingant, J. d'Angelo, unpublished work.
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59
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84912922409
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V. Maine, F. Dumas, J. d'Angelo, unpublished results.
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66
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33645897192
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For an excellent review on the allylic 1,3-strain as a controlling factor in stereoselective transformations, see
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(1989)
Chem. Rev.
, vol.89
, pp. 1841
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Hoffmann1
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68
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84912904872
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a E. Tran, C. Riche, A. Guingant, J. d'Angelo, manuscript in preparation
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71
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0000191460
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John Wiley, New York, Collective
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(1947)
Organic Syntheses
, vol.2
, pp. 503
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74
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84912929560
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“Enantiomerically pure” (R)-1-phenylethylamine (ee ≥ 99.5 %) is available from Celgene Corporation, Warren, NJ, USA.
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75
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37949021580
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The synthesis of enamines and ketimines using molecular sieves
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The silica-alumina catalyst used in our experiments (trade name Ketjencat) was obtained from the Koninklijke Zwavelzuurfabrieken v/h Ketjen N.V., Amsterdam, (the Netherlands). Any fluid cracking catalyst having similar specifications would be well suited for the present purpose. The mixture (1:4) of catalyst and powdered 5 Å molecular sieves was “activated” before use, by calcinating with a free flame under reduced pressure (0.1 Torr).
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(1972)
Recueil des Travaux Chimiques des Pays-Bas
, vol.91
, pp. 605
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Roelofsen1
van Bekkum2
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81
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84912933260
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a E. Tran, C. Riche, A. Guingant, J. d'Angelo, manuscript in preparation
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90
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84912943501
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As generally occurring at the early stages of a given multistep synthetic design, control of enantioselectivity requires to be routinely performed on a large scale. Consequently, asymmetric synthesis should not only be efficient (giving the desired enantiomer with a good chemical yield and an excellent ee), but also simple and economical (sophisticated reaction conditions and/or expensive reagents having therefore to be avoided as far as possible).
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