Synthesis of, and lack of inhibition of a rhamnosidase by, both enantiomers of deoxyrhamnojirimycin and rhamnolactam: β-mannosidase inhibition by δ-lactams

Tetrahedron

Volumn 48, Issue 16, 1992, Pages 3365-3376

  Fairbanks, Anthony J ^a   Carpenter, Neil C ^a   Fleet, George W J ^a   Ramsden, Nigel G ^a   Cenci de Bello, I ^b   Winchester, Bryan G ^b   Al Daher, Samer S ^b   Nagahashi, Gerry ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; ENZYME INHIBITOR; GLYCOSIDASE; GLYCOSIDASE INHIBITOR; RHAMNONOLACTAM; UNCLASSIFIED DRUG;

ARTICLE; DEOXYRHAMNOJIRIMYCIN; DRUG ANALYSIS; DRUG COMPARISON; DRUG DEVELOPMENT; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION;

EID: 0026554003     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(92)85012-4     Document Type: Article

References (40)

1. Plagiarizing Plants: Aminosugars as a Class of Glycosidase Inhibitors
2. Isolation and structure of an unusual cyclic amino alditol from a legume
3. Design synthesis and preliminary evaluation of a potent ?- mannosidase inhibitor: 1,4-dideoxy-1,4-imino-D-mannitol
4. 1,4-Dideoxy-1,4-imino-d-mannitol inhibits glycoprotein processing and mannosidase
5. ?-Lactams: synthesis from D-glucose, and preliminiary evaluation as a fucosidase inhibitor, of L-fuconic-?-lactam
6. SYNTHESIS OFL-ARABINOSE-5-C14