Requirements for hyaluronic acid binding by CD44: A role for the cytoplasmic domain and activation by antibody

Journal of Experimental Medicine

Volumn 175, Issue 1, 1992, Pages 257-266

  Lesley, Jayne ^a   He, Qi ^b   Miyake, Kensuke ^b   Hamann, Alf ^c   Kincade, Paul W ^b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FLUORESCEIN; HERMES ANTIGEN; HYALURONIC ACID; HYALURONIDASE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; CYTOPLASM; GENE EXPRESSION; ISOTOPE LABELING; MOLECULE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DOMAIN; SPLEEN CELL; T CELL LYMPHOMA;

ANIMAL; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; BINDING SITES; CELL ADHESION; CELL LINE; HYALURONIC ACID; LYMPHOMA, T-CELL; MICE; MICE, INBRED AKR; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, LYMPHOCYTE HOMING; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0026537561     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.175.1.257     Document Type: Article

References (65)

1. Omary, M.B., I.S. Trowbridge, M. Letarte, M.F. Kagnoff, and C.M. Isacke. 1988. Structural heterogeneity of human Pgp-1 and its relationship with p85. Immunogenetics. 27:460.
2. Haynes, B.F., M.J. Telen, L.P. Hale, and S.M. Denning. 1989. CD44 - A molecule involved in leukocyte adherence and T cell activation. Immunol. Today. 10:423.
3. Picker, L.J., J. De Los Toyos, M.J. Telen, B.F. Haynes, and E.C. Butcher. 1989. Monoclonal antibodies against the CD44 [In (Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors./. Immunol. 142:2046.
4. Gallatin, W.M., E.A. Wayner, P.A. Hoffman, T. St. John, E.C. Butcher, and W.G. Carter. 1989. Structural homology between lymphocyte receptors for high endothelium and class III extracellular matrix receptor. Proc Natl. Acad. Sci. USA. 86:4654.
5. Quackenbush, E.J., S. Vera, A. Greaves, and M. Letarte. 1990. Confirmation by peptide sequence and co-expression on various cell types of the identity of CD44 and p85 glycoprotein. Mol. Immunol. 27:974.
6. Culty, M., K. Miyake, P.W. Kincade, E. Sikorski, E.C. Butcher, and C.B. Underhill. 1990. The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins. J. Cell Biol. 111:2765.
7. Trowbridge, I.S., J. Lesley, R. Schulte, and J. Trotter. 1982. Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues. Immunogenetics. 15:299.
8. Lesley, J., R. Hyman, and R. Schulte. 1985. Evidence that the Pgp-1 glycoprotein is expressed on thymus-homing progenitor cells of the thymus. Cell Immunol. 91:397.
9. Jalkanen, S., R. Bargatze, L. Herron, and E. Butcher. 1986. A lymphoid cell surface glycoprotein involved in endothelial cell recognition and lymphocyte homing in man. Eur. J. Immunol. 16:1195.
10. Budd, R., J.-C. Cerrotini, C. Horvath, C. Bron, T. Fedraz-zini, R.C. Howe, and H.R. MacDonald. 1987. Distinction of virgin and memory T lymphocytes: stable acquisition of Pgp-1 glycoprotein concomitant with antigenic stimulation. J. Immunol. 138:3120.
11. Miyake, K., K.L. Medina, S.-I. Hayashi, S. Ono, T. Hamaoka, and P.W. Kincade. 1990. Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow culture. J. Exp Med. 171:477.
12. Huet, S.H., H. Groux, B. Caillou, H. Valentin, A.M. Prieur, and A. Bernard. 1989. CD44 contributes to T cell activation. J. Immunol. 143:798.
13. Shimizu, Y., G.A. Seventer, R. Siraganian, L. Wahl, and S. Shaw. 1989. Dual role of the CD44 molecule in T cell adhesion and activation. J. Immunol. 143:2457.
14. Denning, S.M., P.T. Le, K.H. Singer, and B.F. Haynes. 1990. Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation. J. Immunol. 144:7.
15. Jacobson, K., D. O’Dell, B. Holifield, T.L. Murphy, and J.T. August. 1984. Redistribution of a major cell surface glycoprotein during cell movement. J. Cell Biol. 99:1613.
16. Stamenkovic, I., M. Amiot, J.M. Pesando, and B. Seed. 1989. A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family. Cell. 56:1057.
17. Goldstein, L.A., D.F.H. Zhou, L.J. Picker, C.N. Mintz, R.F. Bargatze, J.F. Ding, and E.C. Butcher. 1989. A human leukocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins. Cell. 56:1063.
18. Idzerda, R.L., W.G. Carter, C. Nottenburg, E.A. Wayner, W.M. Gallatin, and T. St. John. 1989. Isolation and DNA sequence of a cDNA clone encoding a lymphocyte adhesion receptor for high endothelium. Proc Natl. Acad. Sci. USA. 86:4659.
19. WolfFe, E.J., W.C. Gause, C.M. Pelfrey, S.M. Holland, A.D. Steinberg, and J.T. August. 1990. The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins. J. Biol. Chem. 265:341.
20. Zhou, P., J. Ding, L. Picker, R. Bargatze, E. Butcher, and D. Goeddel. 1989. Molecular cloning and expression of Pgp-1: the mouse homologue of the human H-CAM (Hermes) lymphocyte homing receptor. J. Immunol. 143:3390.
21. Nottenburg, C., G. Rees, and T. St. John. 1989. Isolation of mouse CD44 cDNA: Structural features are distinct from the primate cDNA. Proc. Natl. Acad. Sci. USA. 86:8521.
22. Lesley, J., R. Schulte, and R. Hyman. 1990. Binding of hyaluronic acid to lymphoid cell lines is inhibited by monoclonal antibodies against Pgp-1. Exp Cell. Res. 187:224.
23. Miyake, K., C.B. Underhill, J. Lesley, and P.W. Kincade. 1990. Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. J. Exp Med. 172:69.
24. Aruffo, A., L. Stamenkovic, M. Melnick, C.B. Underhill, and B. Seed. 1990. CD44 is the principal cell surface receptor for hyaluronate. Cell. 61:1303.
25. Stamenkovic, I., A. Aruffo, M. Amiot, and B. Seed. 1991. The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells. EMBO (Eur. Mol. Biol. Organ.) J. 10:343.
26. Carter, W.G., and E.A. Wayner. 1988. Characterization of the Class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells. J. Biol. Chem. 263:4193.
27. Berg, E.L., L.A. Goldstein, M.A. Jutila, M. Nakache, LJ. Picker, P.R. Streeter, N.W. Wu, D. Zhou, and E.C. Butcher. 1989. Homing receptors and vascular addressins: cell adhesion molecules that direct lymphocyte traffic. Immunol. Rev. 108:5.
28. ki population that binds specifically to hyaluronate. J. Immunol. 146:1422.
29. Hyman, R., J. Lesley, and R. Schulte. 1991. Somatic cell mutants distinguish CD44 expression and hyaluronic acid binding. Immunogenetics. 33:329.
30. Brown, T., T. Bouchard, T. St. John, E. Wagner, and W.G. Carter. 1991. Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons. J. Cell Biol. 113:207.
31. Gunthert, U., M. Hoffman, W. Rudy, S. Reber, M. Zoller, I. Haussman, S. Matzku, A. Wenzel, H. Pontu, and P. Herrlich. 1991. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell. 65:13.
32. Jalkanen, S., M. Jalkanen, R. Bargatze, M. Tammi, and E. Butcher. 1988. Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man. J. Immunol. 141:1615.
33. Goldstein, L.A., and E.C. Butcher. 1990. Identification of mRNA that encodes an alternative form of H-CAM (CD44) in lymphoid and non-lymphoid tissues. Immunogenetics. 32:389.
34. Lucas, M.G., A.M. Green, and MJ. Telon. 1989. Characterization of the serum In(Lu)-related antigen: Identification of a serum protein related to erythrocyte p80. Blood. 73:596.
35. Hyman, R., K. Cunningham, and V. Stallings. 1980. Evidence for a genetic basis for the Class A Thy-1" defect. Immunogenetics. 10:261.
36. Hyman, R., and V. Stallings. 1974. Complementation patterns of Thy-1 variants and evidence that antigen loss variants “preexist” in the parental population.^. Natl. Cancer Inst. (Bethesda). 52:429.
37. Harder, R., H. Uhlig, A. Kashan, B. Schutt, A. Duijvestijn, E.C. Butcher, H.-G. Thiele, and A. Hamann. 1991. Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40 transformed mouse endothelial cell lines: Novel mechanisms mediating basal binding, and a4-integrin dependent cytokine-induced adhesion. Exp Cell Res. In press.
38. Hyman, R., J. Lesley, R. Schulte, and J. Trotter. 1986. Progenitor cells in the thymus: most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface. Cell. Immunol. 101:320.
39. Lesley, J., and I.S. Trowbridge. 1982. Genetic characterization of a polymorphic murine cell-surface glycoprotein. Immunogenetics. 15:313.
40. Miyake, K., I.L. Weissman, J.S. Greenberger, and P.W. Kincade. 1991. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J. Exp Med. 173:599.
41. Miyake, K., K. Medina, K. Ishihara, M. Kimoto, R. Auerbach, and P.W. Kincade. 1991. A V-CAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture. J. Cell Biol. 114:557.
42. Cate, R.L., R.J. Mattaliano, C. Hession, R. Tizard, N.M. Farber, A. Cheung, E.G. Ninfa, A.Z. Frey, D.J. Gash, E.P. Chow, et al. 1986. Isolation of the bovine and human genes for Mullerian Inhibiting Substance and expression of the human gene in animal cells. Cell. 45:685.
43. b gene of C57BL/10 mice. J. Exp Med. 165:1358.
44. He, Q., A.D. Beyers, A.W. Barclay, and A.F. Williams. 1988. A role in transmembrane signalling for the cytoplasmic domain of the CD2 T-lymphocyte surface antigen. Cell. 56:979.
45. de Belden, A.N., and K.O. Wik. 1975. Preparation and properties of fluorescein-labeled hyaluronate. Carbokydr. Res. 44:251.
46. Lesley, J., R. Hyman, R. Schulte, and J. Trotter. 1984. Expression of transferrin receptor on murine hematopoietic progenitors. Cell. Immunol. 83:14.
47. Isacke, C.M., C.A. Sauvage, R. Hyman, J. Lesley, R. Schulte, and I.S. Trowbridge. 1986. Identification and characterization of the human Pgp-1 glycoprotein. Immunogenetics. 23:326.
48. Hamann, A., and H.-G. Thiele. 1989. Molecules and regulation in lymphocyte migration. Immunol. Rev. 108:19.
49. Springer, T. 1990. Adhesion receptors of the immune system. Nature (Land.). 346:425.
50. Shimizu, Y., W. Newman, TV. Gopal, K.J. Horgan, N. Graber, L.D. Beall, G.A. van Seventer, and S. Shaw. 1991. Four molecular pathways of T cell adhesion to endothelial cells: roles for LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions. J. Cell Biol. 113:1203.
51. Dustin, M.L., and T.A. Springer. 1991. Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annu. Rev. Immunol. 9:27.
52. O’Toole, T.E., J.C. Loftus, X. Du, A.A. Glass, Z.M. Rug-geri, S.J. Shattil, E.F. Plow, and M.H. Ginsberg. 1990. Affinity modulation of the Ctnbft integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regulation. 1:883.
53. Altieri, D.C., R. Bader, P.M. Mannucci, and T.S. Edgington. 1988. Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen. J. Cell Biol. 107:1893.
54. Graham, I., and E.J. Brown. 1991. Extracellular calcium results in a conformational change in Mac-1 (CDllb/CD18) on neutrophils: differentiation of adhesion and phagocytosis functions of Mac-1. J. Immunol. 146:685.
55. Neugebauer, K.M., and L.F. Reichardt. 1991. Cell-surface regulation of /3i-integrin activity on developing retinal neurons. Nature (Land.). 350:68.
56. Spertini, O., G.S. Kansas, J.M. Munro, J.D. Griffin, and T.F. Tedder. 1991. Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin. Nature (Lond.). 349:691.
57. llb& (platelet GPIIb-IIIa). Cell. 65:409.
58. 2+ binding epitope on leukocyte integrin a subunits. EMBO (Eur. Mol. Biol. Organ.) J. 8:3759.
59. Figdor, C.G., Y. Van Kooyk, and G.D. Keizer. 1990. On the mode of action of LFA-1. Immunol. Today. 11:277.
60. Detmers, P.A., S.D. Wright, E. Olsen, B. Kimball, and Z.A. Cohn. 1987. Aggregation of complement receptors on human neutrophils in the absence of ligand. J. Cell Biol. 105:1137.
61. Hibbs, M.L., H. Xu, S.A. Stacker, and T.S. Springer. 1991. Regulation of adhesion to I CAM-1 by the cytoplasmic domain of LFA-1 integrin /3 subunit. Science (Wash. DC). 251:1611.
62. Marcantonio, E.E., J. Guan, J.E. Trevithick, and R.O. Hynes. 1990. Mapping of the functional determinants of the integrin (3i cytoplasmic domain by site-directed mutagenesis. Cell Regulation. 1:597.
63. Nagafuchi, A., and M. Takeichi. 1988. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO (Eur. Mol. Biol. Organ.) J. 7:3679.
64. Nagafuchi, A., and M. Takeichi. 1989. Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regulation. 1:37.
65. Murakami, S., K. Miyake, C.H. June, P.W. Kincade, and R.J. Hodes. 1990. IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate. J. Immunol. 145:3618.