Thromboxane receptor blockade reduces renal injury in murine lupus nephritis

Kidney International

Volumn 41, Issue 4, 1992, Pages 973-982

  Spurney, Robert F ^b   Fan, Pang Yen ^b   Ruiz, Phillip ^b   Sanfilippo, Fred ^b   Pisetsky, David S ^b   Coffman, Thomas M ^a  

^a DURHAM VA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOXANE A2; THROMBOXANE RECEPTOR BLOCKING AGENT; VAPIPROST;

ANIMAL EXPERIMENT; ARTICLE; HISTOPATHOLOGY; IMMUNE COMPLEX NEPHRITIS; KIDNEY FAILURE; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; ANTIBODIES, ANTINUCLEAR; BIPHENYL COMPOUNDS; DNA; HEMODYNAMICS; HEPTANOIC ACIDS; IMMUNOGLOBULINS; INTERLEUKIN-1; KIDNEY; LUPUS NEPHRITIS; MICE; MICE, MUTANT STRAINS; RECEPTORS, PROSTAGLANDIN; RECEPTORS, THROMBOXANE; RNA, MESSENGER; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; THROMBOXANE A2;

EID: 0026536096     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1992.149     Document Type: Article

References (47)

1. BAYLIS C: Effect of administered thromboxanes on the intact, normal rat kidney. Renal Physiol 10:110-121, 1987
2. FEIGEN LP, CHAPNIK BM, FLEMMING JE, FLEMMING JM, KADOWITZ PJ: Renal vascular effects of endoperoxide analogues, prostaglandins and arachidonic acid. Am J Physiol 233:H573-H579, 1977
3. WILKES BM, SOLOMON J, MAITA M, MENTO PF: Characterization of glomerular thromboxane receptor sites in the rat. Am J Physiol 256:F1111-F1116, 1989
4. 2 on endoperoxide analogues on cultured rat glomerular mesangial cells. Am J Physiol 251:F1029-F1035, 1986
5. SCHARSCHMIDT LA, LIANOS E, DUNN MJ: Arachidonate metabolites and control of glomerular function. Fed Proc 42:3058-3063, 1983
6. STORK JE, RAHMAN MA, DUNN MJ: Eicosanoids in experimental human renal disease. Am J Med 80(Suppl 1A):34-45, 1986
7. HAMBERG M, SVENSSON J, SAMUELSSON B: Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 72:2994-2998, 1975
8. JOHNSON RJ, GARCIA RL, PRITZL P, ALPERS CE: Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat. Am J Pathol 136:369-374, 1990
9. PURKERSON ML, JOIST JH, YATES J, VALDES A, MORRISON A, KLAHR S: Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. Proc Natl Acad Sci USA 82:193-197, 1985
10. KLAHR S, SCHREINER G, ICHIKAWA I: Progression of renal disease. N Engl J Med 318:1657-1666, 1988
11. KLOTMAN P, BRUGGEMEN L, HASSELL J, HORIGAN E, MARING G, YAMADA Y: Regulation of extracellular matrix by thromboxane. (abstract) Kidney Int 35:294, 1989
12. KELLEY VE, FERRETTI A, IZUI S, STROM TB: A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice. J Immunol 134:1914-1919, 1985
13. KELLEY VE, SNEVE S, MUSINSKI S: Increased renal thromboxane production in murine lupus nephritis. J Clin Invest 77:252-259, 1986
14. SPURNEY RF, BERNSTEIN RJ, RUIZ P, KLOTMAN PE, PISETSKY DS, COFFMAN TM: Physiologic role for enhanced renal thromboxane production in murine lupus nephritis. Prostaglandins 42:15-28, 1991
15. 2 production in patients with systemic lupus erythematosus. J Clin Invest 76:1011-1018, 1985
16. PIERUCCI A, SIMONETTI BM, PECCI G, MAVRIKAKIS G, FERIOZZI S, CINOTTI GA, PATRIGNANI P, CIABATTONI G, PATRONO C: Improvement of renal function with selective thromboxane antagonism in lupus nephritis. N Engl J Med 329:421-425, 1989
17. HORNBY EJ, FOSTER MR, MCCABE PJ, STRATTON LE: The inhibitory effect of GR32191, a thromboxane receptor blocking drug, on human platelet aggregation, adhesion and secretion. Thromb Haemostas 61:429-436, 1989
18. 2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro. Br J Pharmacol 97:783-794, 1989
19. THEOFILOPOULOS AN, DIXON FJ: Murine models of systemic lupus erythematosus. Adv Immunol 37:269-390, 1985
20. SPURNEY RF, RUIZ P, PISETSKY DS, COFFMAN TM: Enhanced renal leukotriene production in murine lupus: Role of lipoxygenase metabolites. Kidney Int 39:95-10, 1991
21. 2 on some isolated smooth muscle preparations. Br J Pharmacol 73:773-778, 1981
22. BRADFORD MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
23. SPURNEY RF, MAVROS SD, COLLINS D, RUIZ P, KLOTMAN PE, COFFMAN TM: Thromboxane receptor blockade improves cyclosporine nephrotoxicity in rats. Prostaglandins 39:135-146, 1990
24. KELLEY VE, CAVALLO T: Urinary protein excretion in normal mice. Renal Physiol 1:235-240, 1978
25. CHIRGWIN JM, PRZYBYLA AE, MACDONALD RJ, RUTTER WJ: Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299, 1979
26. GRAY PW, GLAISTER D, CHEN E, GOEDDEL DV, PENNICA D: Two interleukin-1 genes in the mouse: Cloning and expression of the cDNA for murine interleukin 1β. J Immunol 137:3644-3648, 1986
27. CLEVELAND DW, LOPATS MA, MACDONALD RJ, COWAN NJ, RUTTER WJ, KIRSCHNER MW: Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes. Cell 20:95-105, 1980
28. FEINBERG AP, VOGELSTEIN B: A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13, 1983
29. GILKESON GS, GRUDIER JP, KAROUNOS DG, PISETSKY DS: Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA. J Immunol 142:1482-1486, 1989
30. GILKESON GS, PRITCHARD AJ, PISETSKY DS: Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA. Eur J Immunol 20:1789-1794, 1990
31. SHAPIRO SS, WILK MB: An analysis of variance test for normality. Biometrika 52:591-611, 1965
32. AGRESTI A: Categorical Data Analysis. New York, John Wiley and Sons, 1990
33. BOSWELL JM, YUI MA, ENDRES S, BURT DW, KELLEY VE: Novel and enhanced IL-1 gene expression in autoimmune mice with lupus. J Immunol 141:118-124, 1988
34. SHULTZ PJ, DICORLETO PE, SILVER BJ, ABBOUD HE: Mesangial cells express PDGF mRNAs and proliferate in response to PDGF. Am J Physiol 255:F674-F684, 1988
35. 2 on lymphocyte proliferation. Cell Immunol 90:458-463, 1985
36. 2 mediates augmented polymorphonuclear leukocyte adhesiveness. J Clin Invest 66:406-414, 1980
37. LIANOS EA, ANDRES GA, DUNN MJ: Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. J Clin Invest 72:1439-1448, 1983
38. REMUZZI G, ROSSINI IM, MORELLI C, CARMINATI C, CATTANEO GM, BERTANI T: Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis. J Clin Invest 75:94-101, 1985
39. CYBULSKY AV, LIEBERTHAL W, QUIGG RJ, RENNKE HG, SALANT DJ: A role for thromboxane in complement-mediated glomerular injury. Am J Pathol 128:45-51, 1987
40. FOURNIE GJ: Circulating DNA and lupus nephritis. Kidney Int 33:487-497, 1988
41. WILSON CB, DIXON FJ: The renal response to immunological injury, in The Kidney (3rd ed), edited by BM BRENNER, FC RECTOR Philadelphia, WB Saunders Co, 1986, pp. 800-889
42. 2 during late nephrotoxic serum glomerulonephritis in the rat. J Clin Invest 85:1974-1982, 1990
43. CAMUSSI G, TETTA C, DEREGIBUS MC, BUSSOLINA F, SEGOLONI G, BERCELLONE A: Platelet-activating factor (PAF) in experimentally-induced rabbit acute serum sickness: Role of basophil-derived PAF in immune complex deposition. J Immunol 128:86-94, 1982
44. CATELLA F, NOWAK J, FITZGERALD GA: Measurement of renal and non-renal eicosanoid synthesis. Am J Med 81:23-29, 1986
45. 1 mouse. Clin Nephrol 28:288-294, 1987
46. 2 formation (first of two parts). N Engl J Med 319:689-698, 1988
47. KIMBERLY RP, GILL JR, BOWDEN RE, KEISER HR, PLOTZ PH: Elevated urinary prostaglandins and the effects of aspirin on renal function in lupus erythematosus. Ann Int Med 89:336-341, 1978