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Volumn 19, Issue 1-3, 1992, Pages 109-120

Drug glycosides in oral colon-specific drug delivery

Author keywords

Colon specific drug delivery; Dexamethasone; Dexamethasone d glucoside; Inflammatory bowel disease; Intestinal microfloral mediated drug hydrolysis; Prodrug

Indexed keywords

BETA GLUCOSIDASE; DEXAMETHASONE; DEXAMETHASONE BETA GLUCOSIDE; PRODRUG; UNCLASSIFIED DRUG;

EID: 0026534278     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(92)90069-4     Document Type: Article
Times cited : (34)

References (53)
  • 2
    • 0008690916 scopus 로고
    • Cortisone in ulcerative colitis: final report on a therapeutic trial
    • (1955) Br. Med. J. , vol.2 , pp. 1041-1048
    • Truelove1    Witts2
  • 4
    • 0018129292 scopus 로고
    • Corticosteroids: clinical pharmacology and therapeutic use
    • (1979) Drugs , vol.16 , pp. 238-255
    • Swartz1    Dluhy2
  • 5
    • 0020662018 scopus 로고
    • Toward the optimization of corticosteroids in ulcerative colitis and Crohn's disease
    • (1983) Gut , vol.24 , pp. 177-181
    • Lennard-Jones1
  • 6
    • 0019429364 scopus 로고
    • Effect of prednisolone on prostaglandin synthesis by rectal mucosa in ulcerative colitis: investigation by laminar flow bioassay and radioimmunoassay
    • (1981) Gut , vol.22 , pp. 190-193
    • Hawkey1    Truelove2
  • 9
    • 7344258867 scopus 로고
    • Intrarectal treatment of 100 cases of ulcerative colitis with prednisolone-21-phosphate enemata
    • (1961) BMJ , vol.7 , pp. 165-168
    • Matts1
  • 10
    • 0001099179 scopus 로고
    • Treatment of ulcerative colitis with local hydrocortisone hemisuccinate sodium
    • (1958) BMJ , pp. 1072-1077
    • Truelove1
  • 11
  • 12
    • 0018887725 scopus 로고
    • Rectally administered prednisolone — evidence for a predominantly local action
    • (1980) Gut , vol.21 , pp. 215-218
    • Lee1    Taylor2    James3    Walker4
  • 13
    • 0343289975 scopus 로고
    • Studies on the absorption of hydrocortisone from the colon of patients with idiopathic ulcerative colitis
    • (1958) Tex. Rep. Biol. Med. , vol.16 , pp. 508-514
    • Patterson1
  • 18
    • 0021354414 scopus 로고
    • A colon-specific drug delivery system based on drug glycosides and the glycosidases of colonie bacteria
    • (1984) J. Med. Chem. , vol.27 , pp. 261-266
    • Friend1    Chang2
  • 19
    • 0021992017 scopus 로고
    • Drug glycosides: potential prodrugs for colon-specific drug delivery
    • (1985) J. Med. Chem. , vol.28 , pp. 51-57
    • Friend1    Chang2
  • 26
    • 0001698378 scopus 로고
    • Specificity of the human intestinal disaccharidases and implications for hereditary disaccharide intolerance
    • (1962) J. Clin. Invest. , vol.41 , pp. 463-470
    • Dahlqvist1
  • 29
    • 78651178333 scopus 로고
    • Hydrolytic enzymes of mammalian intestines. Part II Distribution of hydrolytic enzymes in dog, guinea pig, squirrel, albino rat and rabbit intestines
    • (1965) Ind. J. Med. Res. , vol.53 , pp. 410-416
    • Malhorta1    Philip2
  • 39
    • 0014924202 scopus 로고
    • The action of sennosides and related compounds on human colon and rectum
    • (1970) Gut , vol.11 , pp. 1038-1042
    • Hardcastle1    Wilkens2
  • 43
    • 0015014292 scopus 로고
    • Carrageenan-induced ulceration of the large intestine in the guinea pig
    • (1971) Gut , vol.12 , pp. 164-171
    • Watt1    Marcus2
  • 45
    • 0017188069 scopus 로고
    • Animal model: ulcerative colitis induced in guinea pigs with degraded carrageenan
    • (1976) Am. J. Pathol. , vol.84 , pp. 431-434
    • Anverand1    Cohen2
  • 48
    • 0019274486 scopus 로고
    • The comparative prophylactic effects of sulphasalazine, prednisolone, and azathioprine in experimental colonie ulceration
    • (1980) J. Pharm. Pharmacol. , vol.32 , pp. 873-874
    • Watt1    Marcus2    Marcus3
  • 49
    • 0018129292 scopus 로고
    • Corticosteroids: clinical pharmacology and therapeutic use
    • (1979) Drugs , vol.16 , pp. 238-255
    • Swartz1    Dluhy2
  • 50
    • 0019429364 scopus 로고
    • Effect of prostaglandin synthesis by rectal mucosa in ulcerative colitis: investigation by laminar flow bioassay and radioimmoassay
    • (1980) Gut , vol.22 , pp. 190-193
    • Hawkey1    Truelove2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.