A Novel Synthesis and Potent Antiinflammatory Activity of 4-Hydroxy-2(1H)-oxo-1-phenyl-1,8-naphthyridine-3-carboxamides

Journal of Medicinal Chemistry

Volumn 35, Issue 6, 1992, Pages 1130-1136

  Kuroda, Takeshi ^a   Suzuki, Fumio ^a   Tamura, Tadafumi ^a   Ohmori, Kenji ^a   Hosoe, Hisashi ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXY 2(1H) OXO 1 PHENYL 1,8 NAPHTHYRIDINE 3 CARBOXAMIDE DERIVATIVE; 4 HYDROXY 2(1H) OXO 1 PHENYL N (3 PYRIDYL) 1,8 NAPHTHYRIDINE 3 CARBOXAMIDE; AMIDE; ANAPHYLATOXIN; ARACHIDONIC ACID; COMPLEMENT; INDOMETACIN; KF 17515; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTHUS PHENOMENON; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HISTAMINE RELEASE; INFLAMMATION; NONHUMAN; PAW EDEMA; PLEURISY; PRIORITY JOURNAL; RAT; RHEUMATOID ARTHRITIS; STRUCTURE ACTIVITY RELATION;

ANIMAL; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; EDEMA; MALE; NAPHTHYRIDINES; RATS; RATS, INBRED STRAINS; STRUCTURE-ACTIVITY RELATIONSHIP; ZYMOSAN;

EID: 0026533179     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00084a019     Document Type: Article

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