An Exogenous Mouse Mammary Tumor Virus with Properties of Mls-1 a (Mtv-7)

Journal of Experimental Medicine

Volumn 175, Issue 6, 1992, Pages 1623-1633

  Held, Werner ^a   Shakhov, Alexander N ^a   Waanders, Gary ^a   Scarpellino, Leo ^a   Luethy, Roland ^a   Kraehenbuhl, Jean Pierre ^a   MacDonald, H Kobson ^a   Acha Orbea, Hans ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; T LYMPHOCYTE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL INFECTION; GENE DELETION; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; MILK; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; T LYMPHOCYTE SUBPOPULATION;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; CLONING, MOLECULAR; COMPARATIVE STUDY; FEMALE; GENES, VIRAL; LYMPH NODES; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED STRAINS; MILK; MINOR LYMPHOCYTE STIMULATORY ANTIGENS; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0026532864     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.175.6.1623     Document Type: Article

References (81)

1. Festenstein, H. 1973. Immunogenic and biological aspects of in vitro allotransformation (MLR) in the mouse. Transplant. Rev.15:62.
2. Abe, R., and R. Hodes. 1989. T cell recognition of minor lymphocyte stimulating (Mis) gene products. Annu. Rev. Immunol.7:683.
3. Kappler, J.W., U.D. Staerz, J. White, and RC. Marrack. 1988. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature (Lond.). 332:35.
4. MacDonald, H.R., R. Schneider, R.L. Lees, R.K. Howe, H. Acha-Orbea, H. Festenstein, R.M. Zinkernagel, and H. Hen-gartner. 1988. T-cell receptor Vp use predicts reactivity and tolerance to Mls'-encoded antigens.Nature (Lond.).332:40.
5. Pullen, A.M., P. Marrack, and J.W. Kappler. 1988. The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature (Lond.).335:796.
6. c reactive T cells. Nature (Lond.).335:827.
7. Fry, A.M., and L.A. Matis. 1988. Self-tolerance alters T-cell receptor expression in an antigen-specific MHC-restricted immune response. Nature (Lond.).335:830.
8. a antigen. Cell. Immunol.119:412.
9. Davis, M.M., and P.J. Bjorkman. 1988. T-cell antigen receptor genes and T-cell recognition. Nature (Lond.).334:395.
10. a gene products. Proc. Natl. Acad. Sci. USA.86:6293.
11. Okada, C.Y., B. Holzmann, S. Guidos, E. Palmer, and I.L. Weissman. 1990. Characterization of a rat antibody specific for a determinant encoded by the V^7 gene segment. J. Immunol.144:3473.
12. a expressing cells. Nature (Lond.).339:541.
13. Webb, S., C. Morris, and j. Sprent. 1990. Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell63:1249.
14. Jones, L.A., L.T. Chin, D.L. Longo, and A.M. Kruisbeek. 1990. Peripheral clonal elimination of functional T cells. Science (Wash. DC).250:1726.
15. Lynch, D.H., R.E. Gress, B.W. Needleman, S.A. Rosenberg, and R.J. Hodes. 1985. T cell responses to Mis determinants are restricted by crossreactive MHC determinants. J. Immunol. 134:2071.
16. Janeway, C.A.J., and M.E. Katz. 1985. The Immunobiology of the T cell response to Mls-locus-disparate stimulator cells. I. Unidirectionality, new strain combinations, and the role of la antigens. J. Immunol.134:2057.
17. Kappler, J.W., N. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell.49:273.
18. Kappler, J.W., T. Wade, J. White, W. Kushnir, M. Blackman, J. Bill, N. Roehm, and P. Marrack. 1987. A T cell receptor V,8 segment that imparts reactivity to a class II major histocompatibility complex product. Cell.49:263.
19. Bill, J., V. Appel, and E. Palmer. 1988. An analysis of T cell receptor variable region gene expression in major histocompatibility complex disparate mice. Proc Natl. Acad. Sci. USA. 85:9184.
20. Bill, J., O. Kanagawa, D. Woodland, and E. Palmer. 1989. The MHC molecule I-E is necessary but not sufficient for the clonal deletion of 11-bearing T cells. J. Exp Med.169:1405.
21. Okada, C.Y., and I.L. Weissman. 1989. Relative Vg transcript levels in thymus and peripheral lymphoid tissues from various mouse strains. Inverse correlation of I-E and Mis expression with relative abundance of several Vg transcripts in peripheral lymphoid tissues. J. Exp Med.169:1703.
22. Tomonari, K., and E. Lovering. 1988. T-cell receptor-specific monoclonal antibodies against a 11-positive mouse T cell clone. Immunogenetks.28:445.
23. Vacchio, M.S., and R. Hodes. 1989. Selective decrease in T cell receptor V# expression: decreased expression of specific Wg families is associated with expression of multiple MHC and non-MHC gene products. J. Exp Med.170:1335.
24. Vacchio, M.S., J.J. Ryan, and R.J. Hodes. 1990. Characterization of the ligand(s) responsible for negative selection of VpH-and V^12-expressing T cells: effects of a new Mis determinant. J. Exp Med.172:807.
25. Singer, P.A., R.S. Balderas, and A.N. Theofilopoulos. 1990. Thymic selection defines multiple T cell receptor Vg “repertoire phenotypes” at the CD4/CD8 subtype level. EMBO (Eur. Mol. Biol. Organ.) J.9:3641.
26. Six, A., E. Jouvin-Marche, D.Y. Loh, P.A. Cazenave, and P.N. Marche. 1991. Identification of a T cell receptor ft chain variable region, Vg20, that is differentially expressed in various strains of mice. J. Exp Med.174:1263.
27. Acha-Orbea, H., and E. Palmer. 1991. Mis: a retrovirus exploits the immune system. Immunol. Today.12:356.
28. von Boehmer, H., and J. Sprent. 1974. Expression of M locus differences by B cells but not T cells. Nature (Lond.).249:363.
29. a determinants. J. Immunol.143:39.
30. Webb, S.R., A. Okamoto, Y. Ron, and j. Sprent. 1989. Restricted tissue distribution of Mis' determinants. J. Exp Med. 169:1.
31. a mice. Implications for T cell development and autoimmunity. J. Exp Med.169:2149.
32. Acha-Orbea, H., A.N. Shakhov, L. Scarpellino, E. Kolb, V. Mflller, A. Vessaz-Shaw, R. Fuchs, K. Bldchlinger, P. Rolhni, J. Billote, M. Sarafidou, H.R. MacDonald, and H. Diggel-mann. 1991. Clonal deletion of V^14 positive T cells in mammary tumor virus transgenic mice. Nature (Lond.).350:207.
33. Marrack, P., E. Kushnir, and J. Kappler. 1991. A maternally inherited superantigen encoded by a mammary tumor virus. Nature (Lond.).349:524.
34. Woodland, D., M.P. Happ, J. Bill, and E. Palmer. 1990. Requirement for cotolerogenic gene products in the clonal deletion of I-E reactive T cells. Science (Wish. DC).247:964.
35. Dyson, P.J., A.M. Knight, S. Fairchild, E. Simpson, and K. Tomonari. 1991. Genes encoding ligands for deletion of V/jll T cells cosegregate with mammary tumor virus genomes. Nature (Lond.).349:531.
36. Frankel, W.N., C. Rudy, J.M. Coffin, and B.T. Huber. 1991. Linkage of Mis genes to endogenous mammary tumor viruses of inbred mice. Nature (Lond.).349:526.
37. Woodland, D.L., M.P. Happ, K.J. Gollub, and E. Palmer. 1991. An endogenous retrovirus mediating deletion of a3 T cells?Nature (Lond.).349:529.
38. Kozak, C., G. Peters, R. Pauley, V. Morris, R. Michaelides, J. Dudley, M. Green, M. Davisson, O. Prakash, A. Vaidya et al. 1987. A standardized nomenclature for endogenous mouse mammary tumor viruses. J. Virol.61:1651.
39. Choi, Y., J.W. Kappler, and P. Marrack. 1991. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumor virus. Nature (Lond.).350:203.
40. Bentvelzen, P., and J. Hilgers. 1980. Murine mammary tumor virus. In Viral Oncology. G. Klein, editor. Raven Press, Ltd., New York. 311-355.
41. Tsubura, A., M. Inaba, S. Imai, A. Murakami, N. Oyaizu, R. Yasumizu, Y. Ohnishi, H. Tanaka, S. Morii, and S. Ike-hara. 1988. Intervention of T-cells in transportation of mouse mammary tumor virus (milk factor) to mammary gland cells in vivo. Cancer Res.48:6555.
42. Peters, G., S. Brookes, R. Smith, M. Placzek, and C. Dickson. 1989. The mouse homolog of the hst/le-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors. Proc Natl Acad. Sci. USA.86:5678.
43. a-A new congenic mouse strain. Transplantation (Baltimore).37:322.
44. + T cells. J. Exp Med.170:135.
45. Payne, J., B.T. Huber, N.A. Cannon, R. Schneider, M.W. Schilham, H. Acha-Orbea, H.R. MacDonald, and H. Hengartner. 1988. Two monoclonal rat antibodies with specificity for the /3-chain variable region V/36 of the murine T cell receptor. Proc Natl. Acad. Sci. USA.85:7695.
46. Haskins, K., C. Hannum, J. White, N. Roehm, R. Kubo, J. Kappler, and P. Marrack. 1984. The major histocompatibility complex-restricted antigen receptor on T cells. VI. An antibody to a receptor allotype. J. Exp Med.160:452.
47. Staerz, U.D., H. Rammensee, J. Bendetto, and M. Bevan. 1985. Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor. J. Immunol. 134:3994.
48. d haplotype. Immunogenetks.31:333.
49. Utsunomiya, Y., H. Kosaka, and O. Kanagawa. 1991. Differential reactivity of V$9 T cells to minor lymphocyte stimulating antigen in vitro andin vivo. Eur. J. Immunol.21:1007.
50. Dialynas, D.P., D.B. Wilde, P. Marrack, A. Pierres, K.A. Wall, W. Havran, G. Otten, M.R. Loken, M. Pierres, J. Kappler, and F.W. Fitch. 1983. Characterization of the murine antigenic determinant designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol. Rev.74:29.
51. Dialynas, D.P., M.R. Loken, A.L. Glasebrook, and F.W. Fitch. 1981. Lyt-2“/Lyt-3' variants of cloned cytolytic T cell line lack an antigen receptor functional in cytolysis. J. Exp. Med. 153:595.
52. Hart, M.A. 1986. General methods for animal viruses. In Basic Techniques for Transmission Electron Microscopy. M. Hayat, editor. Academic Press Inc. San Diego. 252-257.
53. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY.
54. Feinberg, A.P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem.132:6.
55. Ringold, G., E.Y. Lasfargues, J.M. Bishop, and H.E. Varmus. 1975. Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: Assay by molecular hybridization. Virology.65:135.
56. 1’ mice. J. Exp Med. 175:453.
57. Bentvelzen, P., J. Brinkhof, and F. Westenbrink. 1980. Expression of endogenous mammary tumor virus in mice: its genetic control and relevance to spontaneous carcinogenesis. In Cold Spring Harbor Conferences on Cell Proliferation. Viruses in Naturally Occurring Cancers. M. Essex, editor. Cold Spring Harbor Laboratory. Cold Spring Harbor, NY. 1095-1104.
58. + T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature (Lond.).349:245.
59. + peripheral T cells responding to staphylococcal enterotoxin Bin vivo. Eur. J. Immunol.21:1963.
60. Valk, M.A., van der. 1981. Survival, tumor incidence and gross pathology in 33 mouse strains. In Mammary Tumors in the Mouse. J. Higers and M. Sluyser, editors. Elsevier/North Holland Biomedical Press, 45-00.
61. van Nie, R., and A.A. Verstraeten. 1975. Studies of genetic transmission of mammary tumor virus by GR mice. Int. J. Cancer.16:922.
62. van Nie, R., and J. Hilgers. 1976. Genetic analysis of mammary tumor induction and expression of mammary tumor virus antigen in hormone-treated, ovariectomized GR mice. J. Natl. Cancer Inst. 56:27.
63. Bentvelzen, P., J. Brinkhof, and J.J. Haaijman. 1978. Genetic control of endogenous murine mammary tumor viruses reinvestigated. Eur. J. Cancer.14:1137.
64. Timmermans, A., P. Bentvelzen, P.C. Hageman, and j. Calafat. 1969. Activation of mammary tumor virus in 020 strain mice by X-irradiation and urethane. J. Gen. Virol.4:619.
65. Boot, L.M., P. Bentvelzen, J. Calafat, G. Ropcke, and A. Timmermans. 1970. Interaction of X-ray treatment, a chemical carcinogen, hormones and virus in mammary gland carcinogenesis. Oncology.1:434.
66. Links, J., J. Calafat, F. Buijs, and O. Tol. 1977. Simultaneous chemical induction of MTV and MIVin vitro. Eur. J. Cancer. 13:577.
67. Ruppert, B., W. Wei, D. Medina, and G.H. Heppner. 1978. Effect of chemical carcinogen treatment on the immunoge-nicity of mouse mammary tumors arising from alveolar nodule outgrowth lines. J. Natl. Cancer Inst.61:1165.
68. Pauley, R.J., D. Medina, and S.H. Socher. 1979. Murine mammary tumor virus expression during mammary tumorigenesis in BALB/c mice. J. Virol.29:483.
69. Beutner, U., W.N. Frankel, M.S. Cote, J.M. Coffin, and B.T. Huber. 1992. Mls-1 is encoded by the LTR open reading frame of the mouse mammary tumor provirus Mtv-7. Proc Natl. Acad. Sci. USA. In press.
70. Woodland, D.L., F.E. Lund, M.P. Happ, M.A. Blackman, E. Palmer, and R.B. Corley. 1991. Endogenous superantigen expression is controlled by mouse mammary tumor proviral loci. J. Exp Med.174:1255.
71. Klingman, D., and D.C. Hilt. 1988. The S100 protein family. TIBS (Trends Biochem. Sci.).13:437.
72. Kretsinger, R.H. 1987. Calcium coordination and the calmodulin fold: divergent versus convergent evolution. Cold Spring Harbor Symp Quant. Biol.52:499.
73. Gerke, V., and K. Weber. 1985. The regulatory chain in the p36-kDa substrate complex of viral tyrosine-specific protein kinase is related in sequence to the S-100 protein of glial cells. EMBO (Eur. Mol. Biol. Organ.) J.4:2917.
74. Donehower, L.A., A.L. Huang, and G.L. Hagler. 1981. Regulatory and coding potential of the mouse mammary tumor virus long terminal repeat. J. Virol.37:226.
75. Donehower, L.A., B. Flurdelys, and G.L. Hagler. 1983. Further evidence for the protein coding potential of the mouse mammary tumor virus long terminal repeat: Nucleotide sequence of an endogenous proviral long terminal repeat. J. Virol. 45:941.
76. Fasel, N., K. Pearson, E. Buetti, and H. Diggelmann. 1982. The region of mouse mammary tumor virus DNA containing the long terminal repeat includes a long coding sequence and signals for hormonally regulated transcription. EMBO (Eur. Mol. Biol. Organ.) J.1:3.
77. Majors, J.E., and H.E. Varmus. 1983. Nucleotide sequencing of an apparent proviral copy of env mRNA defines determinants of expression of the mouse mammary tumor virus env gene. J. Virol.47:495.
78. Moore, R., M. Dixon, R. Smith, G. Peters, and C. Dickson. 1987. Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation ofgag andpol.J. ViroL61:480.
79. Kuo, W.-L., L.R. Vilander, M. Huang, and D.O. Peterson. 1988. A transcriptionally defective long terminal repeat within an endogenous copy of mouse mammary tumor virus proviral DNA. J. Virol.62:2394.
80. Crouse, C., and R.J. Pauley. 1989. Molecular cloning and sequencing of the Mtv-1 LTR. Virus Res.12:123.
81. Devereux, J., P. Haberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res.12:387.