Effects of gene transfer into cultured CNS neurons with a replication-defective herpes simplex virus type 1 vector

Molecular Brain Research

Volumn 12, Issue 1-3, 1992, Pages 95-102

  Johnson, Paul A ^a   Yoshida, Kazunari ^b   Gage, Fred H ^b   Friedmann, Theodore ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene transfer; Herpes simplex virus; Herpes vector; lacZ; Neuronal culture

Indexed keywords

VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; GENE TRANSFER; HERPES SIMPLEX VIRUS; HIPPOCAMPUS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; ANIMALS, NEWBORN; ASTROCYTES; BETA-GALACTOSIDASE; CELLS, CULTURED; CEREBRAL CORTEX; CYTOMEGALOVIRUS; ESCHERICHIA COLI; GENES, BACTERIAL; GENES, VIRAL; GENETIC VECTORS; HIPPOCAMPUS; NEUROGLIA; NEURONS; RATS; SIMPLEXVIRUS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION; VIRUS REPLICATION;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 5; MAMMALIA;

EID: 0026526849     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-328X(92)90072-J     Document Type: Article

References (28)

1. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
2. Gene transfer into the nervous system
3. Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants
4. Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides
5. A latent, nonpathogenic HSV-1-derived vector stably expresses β-galactosidase in mouse neurons
6. Identification of the latency-associated transcript promoter by expression of rabbit beta-globin mRNA in mouse sensory nerve ganglia latently infected with a recombinant herpes simplex virus
7. Grafting genetically modified cells to the brain: possibilities for the future
8. A defective HSV-1 vector expresses Escherichia coli β-galactosidase in cultured peripheral neurons
9. Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli β-galactosidase
10. β-galactosidase as a marker in the peripheral and neural tissues of the herpes simplex virus infected mouse
11. Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse
12. Lipofection of cDNAs in the embryonic vertebrate central nervous system
13. Isolation of a herpes simplex virus type 1 mutant deleted for the essential UL42 gene and characterization of its null pheno-type
14. Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1
15. Effects of altered expression of the neural cell adhesion molecule, N-CAM, on early neural development in Xenopus embryos
16. Molecular engineering of the herpes simplex virus genome: insertion of a second L-S junction into the genome causes additional genome inversions
17. Expression of human HPRT mRNA in brains of mice infected with recombinant herpes simplex virus-1 vector
18. Germ-line transformation of mice
19. A prominent serine-rich region in Vmw175, the major regulatory protein of herpes simplex virus type 1 is not essential for virus growth in tissue culture
20. Genetic engineering of novel genomes of large DNA viruses
21. Expression of hepatitis B virus S gene by herpes simplex virus type 1 vectors carrying α- and β-regulated gene chimeras
22. Grafting genetically modified cells into the rat brain: characteristics of E. coli β-galactosidase as a receptor gene
23. The herpes simplex virus amplicon: a new eukaryotic defective-virus cloning-amplifying vector
24. Human herpesviruses: a consideration of the latent state
25. Cis-acting signals involved in the replication and packaging of the herpes simplex virus type 1 DNA
26. Initial interaction herpes simplex virus with cells is binding to heparan sulfate
27. Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes
28. Subcultured astrocytes supress the proliferation of neuroblasts in vitro