Bis-bioreductive agents as hypoxia-selective cytotoxins: Nitracrine N-oxide

International Journal of Radiation Oncology, Biology, Physics

Volumn 22, Issue 4, 1992, Pages 693-696

  Wilson, William R ^a   Van Zijl, Pierre ^a   Denny, William A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Bis bioreductive agent; DNA binding; N oxide metabolism; Nitracrine; Nitracrine N oxide; Spheroids

Indexed keywords

1 AZIRIDINO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; CYTOTOXIN; DNA; INTERCALATING AGENT; MISONIDAZOLE; NITRACRINE; NITRACRINE DERIVATIVE; OXYGEN; PRODRUG; TIRAPAZAMINE;

ANIMAL CELL; CHINESE HAMSTER; CONFERENCE PAPER; DNA BINDING; DRUG ACTIVATION; DRUG CYTOTOXICITY; DRUG METABOLISM; DRUG SELECTIVITY; DRUG STRUCTURE; EQUILIBRIUM DIALYSIS; HYPOXIA; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SPHEROID CELL;

ANIMAL; ANTINEOPLASTIC AGENTS; CELL HYPOXIA; CELL SURVIVAL; HAMSTERS; IN VITRO; NITRACRINE; PRODRUGS; SUPPORT, NON-U.S. GOV'T; TIME FACTORS;

EID: 0026520313     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(92)90505-C     Document Type: Article

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